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Annals of Internal Medicine: COVID-19 and other health system catastrophes

Below please find a summary and link(s) of new coronavirus-related content published today in Annals of Internal Medicine.

25 Apr 2020

Newly identified protein sensor regulates rate of sugar/fat conversion pathway

Scientists in Texas and Pennsylvania have identified a protein sensor that restricts how much sugar and fat our cells convert into energy during periods of starvation.

25 Apr 2020

UCLA scientists receive awards to pursue treatments and vaccines for COVID-19

Three researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards to pursue treatments and vaccines for COVID-19 from the California Institute for Regenerative Medicine, the state's stem cell agency.

25 Apr 2020

New study indicates novel therapies for Duchenne muscular dystrophy

When an actor is unable to perform in the theatre, an understudy--ideally one with some practice in the role--can take her place on stage.

25 Apr 2020

Rice University wins prestigious grant to develop new therapies for sickle cell disease

A Rice University lab has won a prestigious National Institutes of Health grant to pursue gene-editing research it hopes will lead to a cure for sickle cell disease (SCD).

25 Apr 2020

Study: Multidimensional approach works best for tackling nonmedical drug use

Health practitioners are constantly developing new ways to help those with drug and alcohol addictions wean themselves from their substance of choice.

25 Apr 2020

Shortage of coronavirus 'cure' puts pregnant lupus sufferers and their babies at risk

Pregnant lupus sufferers and their babies are at risk as global supplies of an anti-malarial medicine used to treat the disease run dry due to COVID-19 panic.

24 Apr 2020

Research Luxembourg launches Predi-COVID study

The Research Luxembourg COVID-19 task force announces the start of "Predi-COVID", a study that aims to identify important risk factors and biomarkers associated with COVID-19 severity and long-term health consequences of the disease in Luxembourg.

24 Apr 2020

CBT found to be effective in treating binge eating disorders in adolescents

A study published in Psychotherapy and Psychosomatics found cognitive behavioral therapy to be effective, in treating binge eating disorder in adolescence, with lasting results.

24 Apr 2020

Higher blood levels of NETs linked to more severe COVID-19 infection

New research finds a connection between destructive white blood cells and a more severe disease course in patients with COVID-19.

24 Apr 2020

Preliminary findings on obesity and COVID-19 severity

In a Nature Reviews Endocrinology "Comment" authors from the German Center for Diabetes Research, the Boston Children's Hospital and the Harvard T.H. Chan School of Public Health call for more research about the relationships of obesity, disproportionate fat distribution and impaired metabolic health with the severity of COVID-19.

24 Apr 2020

Brain insulin sensitivity linked to body weight and fat distribution

Just where fat is deposited in the body and to what degree a person may benefit from a lifestyle intervention depends, among other things, on how sensitive the brain is to insulin.

24 Apr 2020

New brain cell models created to evaluate therapies for Sanfilippo C syndrome

The Sanfilippo syndrome type C is a severe neurodegenerative disease which appearws during the first years of life and for which there is no treatment yet.

24 Apr 2020

Study looks into COVID‐19 preparedness in Michigan nursing homes

The COVID-19 pandemic has hit some nursing homes especially hard - including in the hotspot state of Michigan. Hundreds of deaths of residents in homes from Seattle to Boston have raised concerns about how well facilities are protecting the 1.3 million older Americans who live in them.

24 Apr 2020

Active ingredient from parasite larvae could help treat asthma

The larvae of the roundworm Heligmosomoides polygyrus bakeri (Hpb) need a very special environment in order to survive: They have to invade the mucosal layer of the intestine in rodents, the only place where they can then develop into adult worms capable of reproduction.

24 Apr 2020

FAU scientists aim to develop a passive vaccine against COVID-19

Nothing less than the development of a passive vaccine against Covid-19 has been undertaken by a team of scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinkum Erlangen and their partners from the Fraunhofer Institute for Cell Therapy and Immunology in Leipzig and the German Primate Centre in Göttingen.

24 Apr 2020

Syphilis bacterium likely uses a single gene to evade immune attack

The bacterium that causes syphilis, Treponema pallidum, likely uses a single gene to escape the immune system, research from UW Medicine in Seattle suggests.

24 Apr 2020

Physical activity makes heart attack patients feel better

Heart attack patients who take part in a lifestyle improvement programme feel better - especially when they do additional physical activity. That's the finding of a large study presented today on ACVC Essentials 4 You, a scientific platform of the European Society of Cardiology.

24 Apr 2020