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Researchers develop new 3D multicomponent dissolvable vaccine platform

In parallel to their current work on a potential coronavirus vaccine, researchers at the University of Pittsburgh School of Medicine have developed a new vaccine delivery system for vaccines using live or attenuated viral vectors: a finger-tip sized patch that contains 400 tiny needles, each just half of one millimeter.

21 Apr 2020

Managing new-onset type 1 diabetes during COVID-19 pandemic with tele-diabetes

Two new case studies highlight the use of tele-diabetes to manage new-onset type 1 diabetes in an adult and an infant during the COVID-19 pandemic.

21 Apr 2020

Malaysian researchers discover new Leptospira strain capable of infecting humans

Malaysian researchers have identified the two species of the Leptospira genus of bacteria responsible for most cases of leptospirosis in the country and discovered a new strain capable of infecting humans.

21 Apr 2020

Immunity to coronavirus infection may help stem the pandemic

The raging coronavirus pandemic is causing immense fear and uncertainty across the world. One of the most distressing aspects of COVID-19 disease is the seemingly large number of unknowns. These include the burning question of immunity. Does a person who was sick with the COVID-19 and then recovered or was infected without symptoms, have immunity against re-infection?

21 Apr 2020

Air pollution, dementia, and cardiovascular disease

A new study published in March 2020 in the journal JAMA Neurology shows an association between air pollution and the development of dementia. However, the role played by cardiovascular disease (CVD) is yet to become apparent.

21 Apr 2020

Virtual reality can help alleviate psychological impact of coronavirus pandemic

A new article discusses the psychological stresses imposed by the coronavirus pandemic and suggests that virtual reality can help alleviate the psychological impact of the need for social isolation.

21 Apr 2020

Scientists identify new biomarker to detect subclinical atherosclerosis

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Instituto de Investigación Sanitaria-Fundación Jiménez Díaz in Madrid have demonstrated that a proteins present in early atheroma plaques--accumulations of cholesterol in the wall of arteries--could be used as a biomarker to detect atherosclerosis in the subclinical phase, before the appearance of symptoms.

21 Apr 2020

Gene therapy could help treat glaucoma, study shows

A new study led by the University of Bristol has shown a common eye condition, glaucoma, could be successfully treated with a single injection using gene therapy, which would improve treatment options, effectiveness and quality of life for many patients.

21 Apr 2020

Tai-Chi-based training associated with improvements in children with ADHD

Attention-deficit/hyperactivity disorder is a highly prevalent neurodevelopmental disorder affecting between 8-10 percent of school-age children.

21 Apr 2020

Study explores how tweets may influence substance abuse in youth

Substance use by youth remains a significant public health concern. While social media provides youth the opportunity to discuss and display substance use-related beliefs and behaviors, little is known about how posting drug-related content, or viewing posted content influences the beliefs and behaviors of youth relative to substance use.

21 Apr 2020

Age-related DNA modifications linked with susceptibility to eye disease

National Eye Institute researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.

21 Apr 2020

Study receives $1 million to explore new approach to treating first responders with PTSD

A study co-led by researchers at McMaster and Western universities on a new approach to treating public safety personnel (PSP) with post-traumatic stress disorder (PTSD) is receiving close to $1 million in funding.

21 Apr 2020

Study finds how metabolism regulates sleep in worms

Can staying up late make you fat? A growing body of research has suggested that poor sleep quality is linked to an increased risk of obesity by deregulating appetite, which in turn leads to more calorie consumption.

21 Apr 2020

New study may offer a breakthrough in treating telomere diseases

Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely.

21 Apr 2020

AI may help eliminate use of biopsy for brain cancer patients

Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors.

21 Apr 2020

CRISPR helps identify new protein potentially involved in Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease.

21 Apr 2020

Study: Behavioral intervention is effective in treating language problems in youth with FXS

A UC Davis Health study found more evidence for the efficacy of telehealth-delivered behavioral intervention in treating language problems in youth with fragile X syndrome (FXS).

21 Apr 2020

A new, potential treatment for nonalcoholic steatohepatitis with fibrosis

In the 2020 April 21 issue of Journal of Hepatology, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis (NASH) with fibrosis and suggested a possibility of the new therapy using cytoglobin (CYGB) inducer for clinical application.

21 Apr 2020

Atmospheric CO2 levels can cause cognitive impairment

As the 21st century progresses, rising atmospheric carbon dioxide (CO2) concentrations will cause urban and indoor levels of the gas to increase, and that may significantly reduce our basic decision-making ability and complex strategic thinking, according to a new CU Boulder-led study.

21 Apr 2020

Many phase II trials overestimate drug efficacy, pose a barrier in drug licensing

Based on a systematic analysis of trials related to rheumatoid arthritis and psoriasis arthritis, a MedUni Vienna study group at the Division of Rheumatology at MedUni Vienna/Vienna General Hospital was able to show that many clinical phase II trials systematically overestimate the efficacy of therapeutics, so that the results of subsequent phase III trials can often be disappointing. Essentially this situation also applies in many other areas.

21 Apr 2020