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Mathematical model for COVID-19 allows for dynamic social distancing and relaxation

Recently, researchers from York University, Toronto, Canada, presented a mathematical model for COVID-19 comprising groups of people with various levels of exposure to the disease based on data from Ontario, Canada. Their work is published on the preprint server medRxiv.

27 Oct 2020

Furin cleavage site and D614G on SARS-CoV-2 spike evolved to balance infectivity, stability, cytopathicity

SARS-CoV-2 is the causative agent of COVID-19 disease, currently raging across the world. The virus has now infected more than 43.89 million individuals and claimed over 1.16 million lives. The study titled, "Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects," is released on the preprint server bioRxiv* in October 2020.

27 Oct 2020

Gut's immune response to SARS-CoV-2 very different from the lung

Megan L. Stanifer et al. study the immune response in the human gut upon SARS-CoV-2 infection. The study published as a bioRxiv* preprint reveals a robust proinflammatory response: a cell type-specific or a tissue-specific regulation of interferon-mediated signaling during SARS-CoV-2 infection.

27 Oct 2020

WSU research sheds new light on a drug that may be used to treat hypertrophic cardiomyopathy

Research at Washington State University sheds new light on one molecule that may be used to treat a heart condition that can lead to stroke, heart attack and other forms of heart disease.

27 Oct 2020

COVID vaccine misinformation lowering people's intent to get vaccinated

A new study by researchers at the Imperial College London and the London School of Hygiene and Tropical Medicine aimed to determine how online misinformation impacts COVID-19 vaccine uptake intent. Further, the team wanted to identify socioeconomic groups at a higher risk of not getting vaccinated and those who are most susceptible to online misinformation.

27 Oct 2020

Inflammasome may play a key role in triggering immune response to cancer

The inflammasome — a protein signaling network that is activated to rid the body of virus or bacteria-infected cells — may play an important role in triggering an immune response to cancer and causing an existing class of drugs to work better against cancers.

27 Oct 2020

Scripps Research scientists uncover potential new strategy for treating eye diseases

Scientists at Scripps Research have uncovered a potential new strategy for treating eye diseases that affect millions of people around the world, often resulting in blindness.

27 Oct 2020

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

27 Oct 2020

Low muscle quality and quantity linked to poor outcomes in colon resection surgery

Low muscle quality and quantity are both predictive of poor outcomes in colon resection surgery, according to a new study published in JAMA Surgery.

27 Oct 2020

Microsurgery improves outcomes in patients experiencing paralysis from Parsonage-Turner Syndrome

Orthopedic surgeons at Hospital for Special Surgery performed successful microsurgery to repair damaged nerves and restore muscle strength and movement to patients experiencing paralysis from Parsonage-Turner Syndrome, according to a study published online ahead of print in The Journal of Hand Surgery.

27 Oct 2020

Bigger households associated with greater odds of SARS-CoV-2 transmission

Household transmission plays a pivotal role in the spread of SARS-CoV-2. The study recommends that it is essential for people to get tested immediately or as soon as symptoms appear. This way, they will take precautions to protect the other members of the family.

27 Oct 2020

Research details new strategy for overcoming treatment resistance by zeroing in on dendritic cells

Many of the most aggressive and hard-to-treat cancers are highly effective at blocking T cells, known as the foot soldiers of the immune system, from reaching and responding to tumors.

27 Oct 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

Scientists uncover surprising players in acute liver failure

Acute liver failure is a devastating, rapidly progressing disease that results in death in 80% of cases, unless an emergency liver transplant is performed. In the developed world, its leading cause is a substantial overdose of acetaminophen, also known as paracetamol.

27 Oct 2020

Rapid CD169 assay for COVID-19 screening

Researchers in France have conducted a study demonstrating the sensitivity of a rapid flow cytometry assay that could be used to screen for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

27 Oct 2020

Research examines COVID-19 transmission patterns in Georgia, U.S.

Researchers from Emory University and the Georgia Department of Public Health have shown that the transmission of coronavirus disease 2019 (COVID-19) in the state of Georgia earlier this year changed over time and varied by age.

27 Oct 2020

Study finds a significant drop in death rates among people with severe COVID-19 in England

Death rates from people with severe COVID-19 in hospital have dropped to around a half of the rate at the peak of the pandemic, new research has revealed.

27 Oct 2020

Research on autophagy and coronavirus, implicates ULK1

Researchers from the University of British Columbia have discovered that the betacoronavirus-encoded papain-like protease disrupts autophagy, partly by targeting ULK1. Their work is reported on the preprint server bioRxiv* in October 2020.

27 Oct 2020

Impaired blood clot contraction predicts imminent postoperative thrombosis

The co-authors are employees of the Protein-Cell Interactions Lab of Kazan Federal University (Natalia G. Evtugina, Alina D. Peshkova, and Lab Head Rustem I. Litvinov) in cooperation with Interregional Clinical Diagnostic Center, Kazan, Russia (Arseniy A. Pichugin) and University of Pennsylvania (John W. Weisel and Rustem I. Litvinov by his primary employment).

27 Oct 2020

Black Hispanic individuals have worse COVID-19 outcomes

Results from a new study led by Boston Medical Center (BMC) demonstrate the disproportionate impact of COVID-19 on Hispanic groups within the US, with the most severe outcomes, including death and intensive care, among Hispanic Black individuals.

27 Oct 2020

Medical Research News

Mathematical model for COVID-19 allows for dynamic social distancing and relaxation

Furin cleavage site and D614G on SARS-CoV-2 spike evolved to balance infectivity, stability, cytopathicity

Gut's immune response to SARS-CoV-2 very different from the lung

WSU research sheds new light on a drug that may be used to treat hypertrophic cardiomyopathy

COVID vaccine misinformation lowering people's intent to get vaccinated

Inflammasome may play a key role in triggering immune response to cancer

Scripps Research scientists uncover potential new strategy for treating eye diseases

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

Low muscle quality and quantity linked to poor outcomes in colon resection surgery

Microsurgery improves outcomes in patients experiencing paralysis from Parsonage-Turner Syndrome

Bigger households associated with greater odds of SARS-CoV-2 transmission

Research details new strategy for overcoming treatment resistance by zeroing in on dendritic cells

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

Scientists uncover surprising players in acute liver failure

Rapid CD169 assay for COVID-19 screening

Research examines COVID-19 transmission patterns in Georgia, U.S.

Study finds a significant drop in death rates among people with severe COVID-19 in England

Research on autophagy and coronavirus, implicates ULK1

Impaired blood clot contraction predicts imminent postoperative thrombosis

Black Hispanic individuals have worse COVID-19 outcomes

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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