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Study: Pleotropic drugs can have both favorable and unfavorable effects on cell growth, survival

The cover for issue 37 of Oncotarget features Figure 7, "The combination of romidepsin and KU60019 is synergistic in a xenograft model of MCL," by Scotto, et al. which reported that the antiproliferative effect induced by histone deactylase inhibitors is associated with the up-regulated expression of the cyclin-dependent kinase inhibitor p21.

17 Sep 2020

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

A recent study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University and published on the preprint server bioRxiv in September 2020 shows that a combination of neutralizing antibodies with intact Fc effector function can effectively reduce the viral load and prevent infection.

17 Sep 2020

Children who experience neglect are more likely to have teen pregnancy

Children who experience neglect are seven times more likely than other abuse victims to have a teen pregnancy say University of Queensland researchers.

17 Sep 2020

Seropositive partners increase risk of COVID-19 but not obstetric complications in pregnant women

While earlier studies have shown the significance of serological testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnant women, their partners have largely been excluded. Now, a new Danish study published on the preprint server medRxiv in September 2020 reports the impact of serologic testing in both pregnant women and their partners, as well as their newborns.

17 Sep 2020

Study shows why bacterial cells behave differently on different types of surfaces

These results from studies in both experimental and theoretical physics may help to improve antibacterial surfaces. The research work was recently published in the journal 'Nanoscale'.

17 Sep 2020

Higher viral loads can increase mortality rate in patients hospitalized with COVID-19 and cancer

Higher viral loads are associated with a greater risk of death among cancer and non-cancer patients hospitalized with coronavirus disease 2019 (COVID-19), researchers report September 15 in the journal Cancer Cell.

17 Sep 2020

Anti-CD73 molecule CPI-006 activates B cell responses to SARS-CoV-2

As the COVID-19 pandemic continues to cause an immense impact across many parts of the world, the role played by immune responses is becoming more evident every day. A recent funded paper published on the preprint server medRxiv* in September 2020 reports the initiation of a Phase I trial of a drug that increases antibody and cell-mediated immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Salk institute to establish world-class consortium to study cellular and tissue aging in humans

The Salk Institute will establish a world-class San Diego Nathan Shock Center (SD-NSC), a consortium with Sanford Burnham Prebys Medical Institute (SBP) and the University of California San Diego (UC San Diego), to study cellular and tissue aging in humans.

17 Sep 2020

Study shows how the body's immune system finds intruding or damaged cells

Research led by Dr. Wonmuk Hwang has led to better understanding on how components of the body's immune system find intruding or damaged cells, which could lead to novel approaches to viral and cancer treatments.

17 Sep 2020

Data scientists use Zhores supercomputer to identify the severity of COVID-19

As part of the anti-COVID-19 program of the Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE), Care Mentor AI data scientists used Skoltech's Zhores supercomputer to enhance pathology detection accuracy.

17 Sep 2020

Scientists examine the sustainability of different models of toothbrush

Researchers at Trinity College Dublin have examined the sustainability of different models of the most commonly used oral health product - the toothbrush - to ascertain which is best for the planet and associated human health.

17 Sep 2020

Researchers develop new strategy to mimic heart-regenerating effects of cardiac cell transplants

Ling Gao and colleagues have developed a strategy that uses exosomes - tiny membrane-bound sacs secreted by cells - to mimic the heart-regenerating effects of cardiac cell transplants, while potentially avoiding risks associated with whole-cell transplants.

17 Sep 2020

Azelastine antihistamine inhibits SARS-CoV-2 infection in nasal tissue in vitro

In a study published on the bioRxiv preprint server, researchers from the University of Pécs, University of Vienna, and CEBINA GmbH, Vienna, show the ability of the antihistamine azelastine to inhibit SARS-CoV-2 infection in human nasal tissue in vitro.

16 Sep 2020

Study looks at how culture can influence women's experiences of disordered eating

"You have to eat!" It's a sentiment that illustrates how central food is to Italian culture, but the woman who uttered these words also happens to be struggling with bulimia nervosa.

16 Sep 2020

Effective interventions needed for increasing CRC screening among African-American men

Out of any other racial group, African American men have the lowest five-year survival rate for colorectal cancer (CRC).

16 Sep 2020

A ferry protein in the pancreas safeguards beta-cells from high-fat diet induced stress

Every time we eat, the glucose level in our body goes up. This spurs our pancreatic machinery into action and through intricate physiological mechanisms, appropriate amounts of insulin are produced, our blood glucose levels are controlled, and we remain healthy.

16 Sep 2020

Changes in risk perception and protective behavior during coronavirus pandemic

In the first week of the coronavirus pandemic, people living in the United States underestimated their chances of catching the virus, or of getting seriously ill from the virus, according to a recently published Caltech-led study.

16 Sep 2020

Researchers uncover how vitamin E acetate might cause lung injury in vapers

E-cigarette, or vaping, associated lung injury (EVALI) has sickened thousands of people, most under the age of 35.

16 Sep 2020

Kessler Foundation tests digital therapeutic device to improve mobility after stroke

Karen Nolan, PhD, of Kessler Foundation, received a grant from MedRhythms to test the company's investigational digital therapeutic device, the Stride Plus, in individuals striving to recover mobility after stroke.

16 Sep 2020

Labeling e-cigarette emissions as 'chemicals' or 'aerosols' increases the perceived risk of exposure

A new study led by Dr. Matthew Rossheim at the George Mason University College of Health and Human Services provides important findings on how labeling of secondhand emissions from e-cigarettes can help more effectively communicate the harm from e-cigarettes and build support for tobacco-free campus policies.

16 Sep 2020

Medical Research News

Study: Pleotropic drugs can have both favorable and unfavorable effects on cell growth, survival

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

Children who experience neglect are more likely to have teen pregnancy

Seropositive partners increase risk of COVID-19 but not obstetric complications in pregnant women

Study shows why bacterial cells behave differently on different types of surfaces

Higher viral loads can increase mortality rate in patients hospitalized with COVID-19 and cancer

Anti-CD73 molecule CPI-006 activates B cell responses to SARS-CoV-2

Salk institute to establish world-class consortium to study cellular and tissue aging in humans

Study shows how the body's immune system finds intruding or damaged cells

Data scientists use Zhores supercomputer to identify the severity of COVID-19

Scientists examine the sustainability of different models of toothbrush

Researchers develop new strategy to mimic heart-regenerating effects of cardiac cell transplants

Azelastine antihistamine inhibits SARS-CoV-2 infection in nasal tissue in vitro

Study looks at how culture can influence women's experiences of disordered eating

Effective interventions needed for increasing CRC screening among African-American men

A ferry protein in the pancreas safeguards beta-cells from high-fat diet induced stress

Changes in risk perception and protective behavior during coronavirus pandemic

Researchers uncover how vitamin E acetate might cause lung injury in vapers

Kessler Foundation tests digital therapeutic device to improve mobility after stroke

Labeling e-cigarette emissions as 'chemicals' or 'aerosols' increases the perceived risk of exposure

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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