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Study sheds new light on the mechanism of COVID-19 infection

The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to research from the Francis Crick Institute published in Nature today.

18 Sep 2020

Researchers describe details of protein linked to genetically inherited Parkinson's disease

In August, a team of researchers at the University of California San Diego published groundbreaking back-to-back studies describing unprecedented details of a protein linked to genetically inherited Parkinson's disease.

18 Sep 2020

Researchers examine problems that hinder the development of medical tourism in Russia

Scientists from Sechenov University interviewed Russian healthcare experts to find out what problems impeded the development of medical tourism in the country most and what measures would help attract foreigners.

18 Sep 2020

Engineered, high-affinity ACE2 receptors neutralize SARS-CoV-2

In a study published in the preprint server bioRxiv, researchers from the Kyoto Prefectural University of Medicine and Osaka University Japan, discuss how they engineered ACE2 to enhance its affinity to RBD in human cells.

17 Sep 2020

Animal data supports efficacy of baricitinib vs SARS-COV-2

The high burden of disease caused by the COVID-19 pandemic has led to much research on effective ways to mitigate the health, social, and economic impact of the spread of the infection. A recent study published on the preprint server bioRxiv* in September 2020 reports on the characteristics of the drug baricitinib when used as monotherapy to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Strong causative link between smoking and bleeding in the brain

A decade ago, in a Nordic Twin Cohort study involving 79,664 twins from Denmark, Finland, and Sweden, researchers looked at risk factors of SAH other than genes.

17 Sep 2020

International researchers set out to compare different countries' COVID-19 responses

The typical measures of the efficacy of a country's response to COVID-19 are the contagion curve and the number of deaths from the disease.

17 Sep 2020

T cells on the front line of COVID-19 response

In the new study, published in the journal Cell, the team has found that the uncoordinated responses produced by the immune system, especially in people who are more than 65 years old, maybe the reason why older adults are more at risk.

17 Sep 2020

Blood protein test could detect severity of head trauma in minutes

A blood protein test could detect the severity of head trauma in under 15 minutes, according to research published recently in the Journal of Neurotrauma.

17 Sep 2020

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients.

17 Sep 2020

Australian stinging tree could pave way for novel painkillers

Australia is well known for having many of the world's most venomous creatures, ranging from snakes, spiders, jellyfish, centipedes, fish, ticks, bees, and ants. 21 of the 25 most venomous snakes in the world are all from Australia. The country is also home to dangerous plants, like the Australian stinging tree.

17 Sep 2020

Researchers identify cause for thrombosis in COVID-19 patients

A new University of Kentucky College of Medicine study may provide answers for why so many COVID-19 patients experience thrombosis, or the formation of blood clots that obstruct blood flow through the circulatory system.

17 Sep 2020

Glucagon resistance: A new biological concept in the fight against diabetes

Researchers from the University of Copenhagen are introducing a new biological concept in the fight against diabetes: glucagon resistance.

17 Sep 2020

Safer UVC light effectively kills SARS-CoV-2

A study conducted by Hiroshima University researchers found that using Ultraviolet C light with a wavelength of 222 nanometers which is safer to use around humans effectively kills SARS-CoV-2 -- the first research in the world to prove its efficacy against the virus that causes COVID-19.

17 Sep 2020

Biomarker predicts disease severity in COVID-19 patients

Airway cell analyses showing an activated immune axis could pinpoint the COVID-19 patients who will most benefit from targeted therapies.

17 Sep 2020

Wearing eyeglasses protects against SARS-CoV-2

A team of scientists from China suggests that people who wear eyeglasses for more than 8 hours a day may be less susceptible to infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published recently in the journal JAMA Ophthalmology.

17 Sep 2020

New drug candidate suppresses SARS-CoV-2 replication

Researchers at Stanford University and Utah State University have developed a novel inhibitor of the coronavirus main protease (Mpro) that effectively suppresses the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Research highlights six key strategies for medical appointment reminders

Researchers from Oregon Health & Science University and the VA Portland Health Care System conducted in-depth interviews with patients at the VA and came up with a series of six recommendations to reduce the number of times patients miss appointments.

17 Sep 2020

Flexibility of glycosylated membrane-bound ACE2 suggests mechanical energy source in opening of SARS-CoV-2 spike

Angiotensin, Angiotensin-Converting Enzyme 2, Cell, Coronavirus, Enzyme, Glycoprotein, Neck, Protein, Receptor, Respiratory, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Syndrome, Virus, SARS-CoV-2, Coronavirus Disease COVID-19,

17 Sep 2020

PPI use linked to worse outcomes in urothelial cancer patients treated with atezolizumab

Proton pump inhibitor (PPI) use was associated with worse outcomes in patients with urothelial cancer treated with the immunotherapeutic atezolizumab (Tecentriq), compared with patients who did not use PPIs.

17 Sep 2020