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Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

The proteasome is a major proteolytic machine that regulates cellular proteostasis through selective degradation of ubiquitylated proteins.

28 Apr 2020

COVID-19 pandemic may signal the end of egalitarian National Health Service

Dr Sabrina Germain, a Senior Lecturer in The City Law School, says the COVID-19 pandemic could signal the end of the National Health Service based on the liberal egalitarian conception of distributive justice.

28 Apr 2020

Research on SARS-CoV-2 spike protein may lead to new vaccines and treatments

The virus that causes COVID-19 is studded on its exterior with "spike proteins," a key component in its ability to infect human cells. Two University of Georgia researchers, Rob Woods and Parastoo Azadi, are investigating the proteins and sugars on the surface of the virus with the goal of finding information that could lead to vaccines and therapeutics.

28 Apr 2020

Researchers develop a new, promising treatment for HIV

A novel means to prevent HIV infection was developed at the University of Nebraska Medical Center that could allow people with or at risk of acquiring the virus to take medicines once a year.

28 Apr 2020

International collaborators propose a new ranking scheme to classify SARS-CoV-2

In November of 2019--likely, even earlier--a tiny entity measuring just a few hundred billionths of a meter in diameter began to tear apart human society on a global scale.

28 Apr 2020

GRAIL to present new data at the American Association for Cancer Research (AACR) annual meeting

GRAIL, Inc., a healthcare company whose mission is to detect cancer early, today announced that new data for its investigational multi-cancer early detection blood test will be presented at the American Association for Cancer Research (AACR) Virtual Annual Meeting I.

From GRAIL, Inc. 28 Apr 2020

Study shows why people with certain heart diseases may be more susceptible to COVID-19

People with certain heart diseases may be more susceptible to worse outcomes with COVID-19, but the reason why has remained unknown.

28 Apr 2020

The world-first personalized nutrition wearable device

An Australian start-up has come with the world's first personalized nutrition wearable device. The device measures dietary biomarkers and helps manage the risk of diseases like Type 2 diabetes.

28 Apr 2020

A new tool for developing gene therapies against cancer, genetic disorders, and blood diseases

A UCLA-led research team today reports that it has developed a new method for delivering DNA into stem cells and immune cells safely, rapidly and economically.

28 Apr 2020

Study marks a major step towards beta cell replacement therapy

The loss of insulin-secreting beta cells by autoimmune destruction leads to type 1 diabetes. Clinical islet cell transplantation has the potential to cure diabetes, but donor pancreases are rare.

28 Apr 2020

Researchers identify a new risk factor for multiple neurodegenerative diseases

Scientists at the HudsonAlpha Institute for Biotechnology, the University of California, San Francisco (UCSF), and the University of Alabama at Birmingham (UAB), have identified a new risk factor for multiple neurodegenerative diseases.

28 Apr 2020

COVID-19 can trigger serious inflammatory-related cardiovascular problems

The coronavirus disease (COVID-19) is potentially fatal for vulnerable populations like seniors who over 60 years old, and those with underlying medical conditions, like heart disease, diabetes, and lung disease. Reports show that patients are suffering from heart impairment caused by COVID-19. A new study sheds light on the effect of the novel coronavirus on the heart, causing cardiovascular problems, even in those without underlying heart conditions.

27 Apr 2020

Using neutralising antibodies in the fight against COVID-19

While many scientists and pharmaceutical companies are racing to develop a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, there is also an urgent need for a coronavirus disease (COVID-19) treatment. The potent virus has now spread to 210 countries and territories, affecting more than 3.04 million people. Now, a team of German scientists is working on using antibodies to prevent and treat COVID-19.

27 Apr 2020

Study looks at outcomes of COVID‐19 during pregnancy

With the world at a standstill as the novel coronavirus SARS-CoV-2 spreads across the globe, governments are struggling to slow down its wrath. Worldwide public health responses and emergency measures have been implemented to stem the impact of the coronavirus disease (COVID-19).

27 Apr 2020

The approved dose of ivermectin alone not useful in treating COVID-19

A new paper published on the preprint server medRxiv in April 2020 shows that the use of the already approved drug ivermectin in clinical trials to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)s not feasible. This contradicts earlier reports of its ability to suppress the virus in vitro.

27 Apr 2020

New, previously unknown form of familial cold urticaria discovered

Skin rash combined with head and joint pain: these are the symptoms which patients with familial (hereditary) cold urticaria develop when exposed to temperatures below 15 °C.

27 Apr 2020

Researchers develop new method for remotely stimulating activity in deep brain regions

University of Texas at Dallas researchers have developed a promising method for remotely stimulating activity in deep brain regions, advancing understanding of how molecules act in the brain and paving the way for better cancer treatments and therapies for other diseases.

27 Apr 2020

Olfactory impairment linked with milder clinical course in COVID-19

Following an earlier study that validated the loss of smell and taste as indicators of SARS-CoV-2 infection, researchers at UC San Diego Health report in newly published findings that olfactory impairment suggests the resulting COVID-19 disease is more likely to be mild to moderate, a potential early indicator that could help health care providers determine which patients may require hospitalization.

27 Apr 2020

Gut microbiome influences pattern of activation in rat’s brain during opioid addiction

When Sierra Simpson was in college, she was sick for a year with recurring fevers and vomiting. Her doctors couldn't figure out what she had. Suspecting a bacterial infection, they tried treating her with high doses of antibiotics.

27 Apr 2020

$Study provides an overview of the burden, management of fragility fractures$

Study provides an overview of the burden, management of fragility fractures

A new study provides an overview and comparison of the burden and management of fragility fractures due to osteoporosis in the five largest countries in Europe (France, Germany, Italy, Spain, and the United Kingdom) as well as Sweden.

27 Apr 2020