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Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid "plaques," which have been the focus of Alzheimer's research and drug development for decades, was found to be of little utility in predicting how damage would unfold as the disease progressed.

2 Jan 2020

New trial shows how parents can avoid bringing dangerous bacteria into the NICU

For sick or prematurely born babies spending their first days of life in a hospital's neonatal intensive care unit, the soothing voice and gentle touch of a loving parent can have a tremendous impact toward a positive outcome -- that is, unless mom or dad's visit leaves the infant with something extra: a dangerous bacterial infection.

31 Dec 2019

Bile acids help norovirus to infect cells of the small intestine

A new study led by researchers at Baylor College of Medicine and published in the Proceedings of the National Academy of Sciences reveals that human noroviruses, the leading viral cause of foodborne illness and acute diarrhea around the world, infect cells of the small intestine by piggybacking on a normal cellular process called endocytosis that cells use to acquire materials from their environment.

31 Dec 2019

Obj-SCD predicts future amyloid accumulation and neurodegeneration

Writing in the December 30, 2019 online issue of Neurology, researchers at University of California San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report that accumulating amyloid -- an abnormal protein linked to neurodegenerative conditions such as Alzheimer's disease -- occurred faster among persons deemed to have "objectively-defined subtle cognitive difficulties" (Obj-SCD) than among persons considered to be "cognitively normal."

31 Dec 2019

New dementia vaccine may proceed to clinical trials after successful testing

A preventive treatment for dementia may proceed to clinical trials after successful animal testing.

31 Dec 2019

Research review discusses anti-cancer properties of turmeric

Curcumin, a polyphenol extracted from Curcuma longa, also known as turmeric, has gained attention from scientists worldwide for its biological properties as an antioxidant, anti-inflammatory, antimicrobial, and antiviral agent.

31 Dec 2019

Amyloid plaques may not necessarily come first in Alzheimer's disease, suggests new study

The scientific community has long believed that beta-amyloid, a protein that can clump together and form sticky plaques in the brain, is the first sign of Alzheimer's disease. Beta-amyloid then leads to other brain changes including neurodegeneration and eventually to thinking and memory problems. But a new study challenges that theory.

30 Dec 2019

New combination of antibodies leads to more effective tumor destruction

The simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors.

30 Dec 2019

Consumers feel empowered and confused by direct-to-consumer fertility tests, study reveals

Direct-to-consumer hormone-based "fertility testing" for women is viewed by consumers as both an alternative, empowering tool for family planning, and a confusing and misleading one, according to the results of a new study from Penn Medicine.

30 Dec 2019

Individualized pelvic physical therapy decreases incontinence, pain in post-prostatectomy patients

For decades, therapy to strengthen pelvic muscles has been the standard treatment for men dealing with urinary incontinence after prostate surgery. But a new study from UT Southwestern's Departments of Urology and Physical Medicine and Rehabilitation suggests that may not be the best approach.

30 Dec 2019

Exposure to pyrethroid insecticides associated with cardiovascular death

A new study from the University of Iowa suggests that people who have higher levels of a chemical in their body that indicates exposure to commonly used insecticides die of cardiovascular disease at a significantly higher rate.

30 Dec 2019

Closing of local automotive assembly plants may lead to rise in opioid overdose deaths

Closing of local automotive assembly plants may lead to increases in deaths from opioid overdose, according to a study led by researchers at the Perelman School of Medicine at the University of Pennsylvania and the Massachusetts General Hospital.

30 Dec 2019

Exposure of pregnant women to persistent organic pollutants linked to smaller fetuses

Pregnant women exposed to persistent organic pollutants, or POPs, had slightly smaller fetuses than women who haven't been exposed to these chemicals, according to an analysis of ultrasound scans by researchers at the National Institutes of Health and other institutions.

30 Dec 2019

Children who drank whole milk had lower odds of being overweight or obese, study finds

A systematic review and meta-analysis led by St. Michael's Hospital of Unity Health Toronto found children who drank whole milk had 40 per cent lower odds of being overweight or obese compared with children who consumed reduced-fat milk.

30 Dec 2019

Diarrhea in young children linked to La Niña climate conditions

A study in Botswana by Columbia University Mailman School of Public Health scientists finds that spikes in cases of life-threatening diarrhea in young children are associated with La Niña climate conditions.

30 Dec 2019

Pulmonary fibrosis associated with short and long sleep duration

Scientists have discovered that people who regularly sleep for more than 11 hours or less than 4 hours are 2-3 times more likely to have the incurable disease, pulmonary fibrosis, compared to those that sleep for 7 hours in a day. They attribute this association to the body clock.

30 Dec 2019

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Combination treatment reduces breast cancer development in mice

Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy.

30 Dec 2019

A new deep learning approach to predict disease-associated mutations

During the past years, artificial intelligence (AI) -- the capability of a machine to mimic human behavior -- has become a key player in high-techs like drug development projects.

28 Dec 2019

One dose of HPV vaccine may prevent infection from cancer-causing virus, study reveals

A new study revealed that one dose of the HPV vaccine may prevent infection from the potential cancer-causing virus, according to research published in JAMA Network Open from The University of Texas Health Science Center at Houston.

28 Dec 2019

Medical Research News

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

New trial shows how parents can avoid bringing dangerous bacteria into the NICU

Bile acids help norovirus to infect cells of the small intestine

Obj-SCD predicts future amyloid accumulation and neurodegeneration

New dementia vaccine may proceed to clinical trials after successful testing

Research review discusses anti-cancer properties of turmeric

Amyloid plaques may not necessarily come first in Alzheimer's disease, suggests new study

New combination of antibodies leads to more effective tumor destruction

Consumers feel empowered and confused by direct-to-consumer fertility tests, study reveals

Individualized pelvic physical therapy decreases incontinence, pain in post-prostatectomy patients

Exposure to pyrethroid insecticides associated with cardiovascular death

Closing of local automotive assembly plants may lead to rise in opioid overdose deaths

Exposure of pregnant women to persistent organic pollutants linked to smaller fetuses

Children who drank whole milk had lower odds of being overweight or obese, study finds

Diarrhea in young children linked to La Niña climate conditions

Pulmonary fibrosis associated with short and long sleep duration

Scientists discover potential drug compounds that target common type of liver cancer

Combination treatment reduces breast cancer development in mice

A new deep learning approach to predict disease-associated mutations

One dose of HPV vaccine may prevent infection from cancer-causing virus, study reveals

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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