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Study helps explain why previous attempts to develop a staph vaccine have failed

Staph bacteria, the leading cause of potentially dangerous skin infections, are most feared for the drug-resistant strains that have become a serious threat to public health.

26 Dec 2019

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome.

26 Dec 2019

New spatiomolecular map may advance understanding of the brain's decision-making area

Researchers at Karolinska Institutet have come one step closer toward understanding how the part of our brain that is central for decision-making and the development of addiction is organized on a molecular level.

26 Dec 2019

Many stomach cancer patients under 60 have a 'genetically and clinically distinct' disease

Many people under 60 who develop stomach cancer have a "genetically and clinically distinct" disease, new Mayo Clinic research has discovered.

26 Dec 2019

Common cardiac blood test before surgery can predict post-operative complications

A common cardiac blood test done before surgery can predict who will experience adverse outcomes after most types of surgery, says an international study led by Hamilton researchers.

23 Dec 2019

Study measures brain injury from boxing, MMA in younger and older fighters

For boxers and mixed martial arts (MMA) fighters, is there a safe level of exposure to head trauma? A new study shows different effects in the brain for younger, current fighters compared to older, retired fighters.

23 Dec 2019

Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs.

23 Dec 2019

Immunologists discover new RIPK1 mechanism that leads to cell death

Scientists at St. Jude Children's Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process.

23 Dec 2019

Scientists explore women's knowledge and perceptions of breast density, cancer risk

Breast density is an important risk factor for breast cancer but no study had asked women what they know or think about breast density in relation to screening they have had.

23 Dec 2019

California's vaccine policy improved immunization coverage

In 2016, California removed vaccine exemptions for non-medical reasons, such as parental hesitancy, to requirements for school entry. In other words, California children needed to have a medical reason to refuse vaccination if they wanted to join kindergarten. In so doing, the state may have paved the way for a higher percentage of vaccination recipients at both county and state level, says a new study published this week in the journal PLOS Medicine.

23 Dec 2019

Obesity linked to increased risk of cardiotoxicity in chemotherapy-treated patients with breast cancer

Anthracyclines remain a cornerstone of breast cancer therapy in combination with new-generation targeted drugs such as trastuzumab. Both types of drugs are major culprits in chemotherapy-induced heart disease.

23 Dec 2019

Super fast novel device catches and identifies viruses

A new study published in the journal Proceedings of the National Academy of Sciences on December 23, 2019, describes a novel device developed by a team of researchers at Penn State and New York University. Not only can this instrument capture different types of virus, it can tell what kind they are.

23 Dec 2019

New 'fishing' technique to detect thousands of proteins

A new study published today in the journal Nature Cell Biology reports the use of a novel fishing method, under microscopy, to pick up thousands of proteins that are involved in supervising how the cell skeleton is assembled.

23 Dec 2019

Research findings may one day help keep ALS at bay

A new study published in the journal Nature Medicine on December 23, 2019, shows how to silence a defective gene responsible for the degeneration of the motor neurons in Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), in adult mice. This could help prevent disease progression if the condition is already symptomatic, and even suppress the illness if it has not yet started.

23 Dec 2019

Plant-rich diet protects against foodborne pathogens, mice study shows

Mice fed a plant-rich diet are less susceptible to gastrointestinal infection from a pathogen such as the one currently under investigation for a widespread E. coli outbreak tied to romaine lettuce, UT Southwestern researchers report.

23 Dec 2019

Immunosupressant combination therapy for glioblastoma shows promise

Researchers from the University of Texas have found an immunosuppressing target for the treatment of glioblastoma. In mice studies the team has identified CD73 macrophages which could be used to treat the cancers. The team also performed studies on human tumours to arrive at their conclusions. The study was published in the latest issue of the journal Nature Medicine this week.

23 Dec 2019

Autism risk in children could be predicted by mutations in paternal sperm

Researchers from the University of California, San Diego, have found that mutations present in the sperms of the father could be predictors of autism in the offspring, in a landmark study. These mutations, if quantified could help ascertain the risk say the researchers. The new study appears this week in the latest issue of the journal Nature Medicine.

23 Dec 2019

Scientists develop 3D atlas of bone marrow to help study blood diseases

The bone marrow, which is the spongy and viscous tissue that fills the bone, is the site of blood cell formation or hematopoiesis. If the bone marrow doesn’t work properly, it can lead to many blood diseases, including leukemia, sickle cell anemia, and lymphoma, among others.

23 Dec 2019

Scientists unveil how Zika virus replicates

The World Health Organization (WHO) declared the Zika virus infection a global threat during the peak of its outbreak in 2016. Since then, scientists and health experts raced to understand the virus better to develop novel and effective vaccines and treatments for the disease. Now, a team of researchers in China revealed how a protein in the virus reshapes its host to boost viral replication.

23 Dec 2019

Stay-at-home dads continue to face major social hurdles and stigmas

Fathers make an important contribution when they stay at home as primary caregiver for their children - but they continue to face major social hurdles and stigmas, according to Flinders University researchers in a new book, Men Caregiving and the Media: The Dad Dilemma, which examines why the relationship between caregiving and masculinity is seldom celebrated.

23 Dec 2019