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ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

$5 million in federal funding to accelerate potential treatments for urea cycle disorders

An international research consortium co-led by Andrea L. Gropman, M.D., at Children's National Hospital has received $5 million in federal funding as part of an overall effort to better understand rare diseases and accelerate potential treatments to patients.

24 Oct 2019

Genetic variations linked to declines in blood oxygen levels during sleep identified

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia, and death.

24 Oct 2019

Mayo Clinic study explores patient privacy in MRI research

Though identifying data typically are removed from medical image files before they are shared for research, a Mayo Clinic study finds that this may not be enough to protect patient privacy.

24 Oct 2019

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Sarcomas - cancers that arise from transformed mesenchymal cells (a type of connective tissue) - are quite deadly. Gastrointestinal stromal tumors are the most common human sarcoma and are initiated by activating mutations in the KIT receptor tyrosine kinase.

24 Oct 2019

Infant formula containing MFGM contributes to beneficial cognitive, respiratory health outcomes

Results from a clinical trial published today in the Journal of Pediatrics show infants who consume formula containing milk fat globule membrane (MFGM) -- a complex layer that normally surrounds fat in milk -- score higher in tests of cognitive, language and motor development by their first birthdays than infants consuming a milk-based formula that didn't contain MFGM.

24 Oct 2019

Vaccine for Lassa fever set to enter clinical testing in humans

There is currently no vaccine for the Lassa arenavirus, which causes Lassa fever. This hemorrhagic fever, endemic in West Africa, infects up to 300,000 people each year.

24 Oct 2019

Scientists find new strains of human adenovirus in Singapore

Human adenovirus (HAdV) infections in Singapore and Malaysia have caused severe respiratory disease among children and adults in recent years, but scientists still don't know whether these outbreaks are due to new or re-emerging virus strains.

24 Oct 2019

Behavioral health program has positive impact on employees with depression or anxiety

An employer-sponsored behavioral health program can reduce symptoms in employees with depression and anxiety, reports a study in the October Journal of Occupational and Environmental Medicine.

24 Oct 2019

Metacognitive therapy significantly reduces risk of relapse

Depression is one of the most common mental disorders worldwide. It affects both individuals and society as a whole, in the form of lost work productivity, high mortality and lower quality of life.

24 Oct 2019

Older women with DCIS gain no benefit from sentinel lymph node biopsy

Older women with a very early, non-invasive breast cancer known as ductal carcinoma in situ (DCIS) gain no long-term benefit from undergoing a sentinel lymph node biopsy to see if the cancer has spread, new research by the Yale School of Public Health has found.

24 Oct 2019

Study: More than 300 million people affected worldwide by rare diseases

Rare diseases represent a global problem. Until now, the lack of data made it difficult to estimate their prevalence.

24 Oct 2019

Newly discovered protein is key to recycling aging mitochondria

Aging, and the mechanics behind it, remains one of the most closely guarded secrets of life.

24 Oct 2019

Detecting neurotransmitters at the lowest concentrations

Dopamine, serotonin, adrenalin... The smooth functioning of the human brain depends on their correct proportions. Any disturbances mean diseases.

24 Oct 2019

Australian honey has exceptionally high levels of antibacterial activity

Australia has at least seven Leptospermum species that produce honey with exceptionally high levels of antibacterial activity, providing the scientific basis to facilitate the entry of Australian honey producers into premium medicinal markets.

24 Oct 2019

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

An international team of experts led by researchers in the Perelman School of Medicine at the University of Pennsylvania and University of Glasgow has been awarded a $9.7 million, five-year grant from the National Institute of Neurological Disorders and Stroke and National Institute for Aging to establish CONNECT-TBI--a program spanning 12 institutions which will study traumatic brain injury and related neurodegenerative diseases.

24 Oct 2019

Direct current stimulation device aids in spinal fusion procedure

Spine surgeons in the U.S. perform more than 400,000 spinal fusions each year as a way to ease back pain and prevent vertebrae in the spine from wiggling around and doing more damage.

24 Oct 2019

Risk factors for unemployment with multiple sclerosis vary by age, study finds

A recent study by Kessler Foundation researchers explored numerous factors that contribute to the high unemployment rate among individuals of different ages with multiple sclerosis.

24 Oct 2019

Researchers discover unexpected role of mTORC2 protein in colorectal cancer

New results from researchers at MedUni Vienna's Center for Pathobiochemistry and Genetics show that a protein called mTORC2, which is the target of newly developed cancer drugs, is not even active in colorectal cancer. mTORC2 activity was only found in certain immune cells, which actually need this protein to fight cancer cells.

24 Oct 2019

Study seeks participants with VCFS-related psychosis to help create biobank of cerebral organoids

A landmark study is calling for at least 50 people in the U.S. with Velo-Cardio-Facial Syndrome (VCFS)-related psychosis to provide blood samples to create the world’s largest VCFS biobank to date of tiny spheres of neural tissue called "cerebral organoids."

24 Oct 2019

Medical Research News

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

$5 million in federal funding to accelerate potential treatments for urea cycle disorders

Genetic variations linked to declines in blood oxygen levels during sleep identified

Mayo Clinic study explores patient privacy in MRI research

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Infant formula containing MFGM contributes to beneficial cognitive, respiratory health outcomes

Vaccine for Lassa fever set to enter clinical testing in humans

Scientists find new strains of human adenovirus in Singapore

Behavioral health program has positive impact on employees with depression or anxiety

Metacognitive therapy significantly reduces risk of relapse

Older women with DCIS gain no benefit from sentinel lymph node biopsy

Study: More than 300 million people affected worldwide by rare diseases

Newly discovered protein is key to recycling aging mitochondria

Detecting neurotransmitters at the lowest concentrations

Australian honey has exceptionally high levels of antibacterial activity

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

Direct current stimulation device aids in spinal fusion procedure

Risk factors for unemployment with multiple sclerosis vary by age, study finds

Researchers discover unexpected role of mTORC2 protein in colorectal cancer

Study seeks participants with VCFS-related psychosis to help create biobank of cerebral organoids

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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