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Mutations in SARS-CoV-2 may explain its dominance and spread

Researchers at Dokuz Eylül University, Turkey, have identified mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may have contributed to its dominance in Europe and elsewhere.

21 May 2020

Scientists create a detailed map of how carcinogens trigger breast cancer development

In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger the disease.

21 May 2020

Just a little physical activity can have big impact for women with high-risk breast cancer

Results of a comprehensive analysis of exercise and its protective role for high-risk breast cancer patients show that women who exercise not only live longer, but also are more likely to remain cancer-free after their treatment. What's more, the study suggests that even a modest amount of exercise can be beneficial.

21 May 2020

Study shows selenium-containing compounds inhibit SARS-CoV-2 replication and assembly

A recent paper by researchers from the Netherlands and Poland provides evidence that modified ebselen derivatives may serve as highly promising prospective drugs against coronavirus disease 2019 (COVID-19). The manuscript is freely available on the bioRxiv* preprint server.

21 May 2020

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis and other neurodegenerative diseases, such as Hereditary Spastic Paraplegia and Primary Lateral Sclerosis.

21 May 2020

Computational immunology paves the way for SARS-CoV-2 peptide cocktail vaccine candidate

By employing an immunoinformatics approach, a new study available on the preprint server bioRxiv* shows how the combination of peptides designed from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid phosphoprotein and spike glycoprotein may trigger an improved immunological response with respectable safety profile, informing, in turn, further vaccine development.

21 May 2020

COVID-19 in farmed Mink in the Netherlands

A new study published on the preprint server bioRxiv in May 2020 reports the development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in farmed mink in two locations in the Netherlands.

21 May 2020

Does abdominal fat affect COVID-19 outcomes?

As the COVID-19 pandemic seems to be slowing down in some parts of the world slightly but accelerating in others, scientists are investigating the role played by a host of factors that might impact the final outcome. A new study published on the preprint server medRxiv* in May 2020 examines the role of abdominal fat (visceral obesity, VO) in severe COVID-19.

21 May 2020

Researchers receive $5 million to study two types of parasitic infection

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5 million to study two types of parasitic worm infection that cause devastating illness in millions of people worldwide.

21 May 2020

Lower mean number of household members associated with more COVID-19 cases

Regions of Italy with higher family fragmentation and a high number of residential nursing homes experienced the highest rate of COVID-19 infections in people over age 80, according to a new study published May 21, 2020 in the open-access journal PLOS ONE by Giuseppe Liotta of the University of Rome, Italy, and colleagues.

21 May 2020

Researchers receive $5.75 million to study link between obesity, inflammation and pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from the National Cancer Institute to study the correlation between obesity, inflammation and pancreatic cancer.

21 May 2020

Lowering blood pressure reduces risk of developing dementia, research shows

Research completed in NUI Galway has shown that lowering blood pressure by taking blood pressure medications reduces the risk of developing dementia and cognitive impairment by 7%.

21 May 2020

Bariatric surgery may alter gene expression in fat tissue

Altered gene expression in fat tissue may help explain why individuals who have regained weight after weight loss surgery still experience benefits such as metabolic improvements and a reduced risk of type 2 diabetes.

21 May 2020

Scientists use new model to develop cancer stem cells

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma (HCC).

21 May 2020

Paper-based device measures lithium ion concentration in blood of bipolar disorder patients

A group of Hokkaido University researchers has developed a paper-based device that can easily and cheaply measure lithium ion concentration in blood, which could greatly help bipolar disorder patients.

21 May 2020

Study: COVID-19 infection may cause subacute thyroiditis

COVID-19 infection may cause subacute thyroiditis, according to a new case study published in The Journal of Clinical Endocrinology & Metabolism.

21 May 2020

Synchrony within a group may enhance cohesion and influence performance

Group work and cooperation are crucial in everyday life. As such, it is important to explore the avenues by which synchrony within a group may enhance cohesion and influence performance.

21 May 2020

Comprehensive review of clioquinol drug gives valuable insights

CQ is an old drug that was commonly used to treat fungal/protozoal infections of the gastrointestinal tract. Patients in Japan taking it developed subacute myelo-optic neuropathy which resulted in CQ being discontinued for oral use. Recently, extensive research has been done in regards to CQ's use for cancer treatment.

21 May 2020

Producing virus-specific antibodies after COVID-19

In order to design effective vaccines for COVID-19, we need to understand our immune responses. News-Medical speaks to Professor Chen Dong to find out more.

21 May 2020

Study: Older people with persistent pain in rural areas face challenges in accessing healthcare

A study led by Keele University has found that older people with persistent pain living in rural areas face challenges in accessing healthcare, which may mean they are less likely to seek treatment or engage in effective self-management.

21 May 2020

Medical Research News

Mutations in SARS-CoV-2 may explain its dominance and spread

Scientists create a detailed map of how carcinogens trigger breast cancer development

Just a little physical activity can have big impact for women with high-risk breast cancer

Study shows selenium-containing compounds inhibit SARS-CoV-2 replication and assembly

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Computational immunology paves the way for SARS-CoV-2 peptide cocktail vaccine candidate

COVID-19 in farmed Mink in the Netherlands

Does abdominal fat affect COVID-19 outcomes?

Researchers receive $5 million to study two types of parasitic infection

Lower mean number of household members associated with more COVID-19 cases

Researchers receive $5.75 million to study link between obesity, inflammation and pancreatic cancer

Lowering blood pressure reduces risk of developing dementia, research shows

Bariatric surgery may alter gene expression in fat tissue

Scientists use new model to develop cancer stem cells

Paper-based device measures lithium ion concentration in blood of bipolar disorder patients

Study: COVID-19 infection may cause subacute thyroiditis

Synchrony within a group may enhance cohesion and influence performance

Comprehensive review of clioquinol drug gives valuable insights

Producing virus-specific antibodies after COVID-19

Study: Older people with persistent pain in rural areas face challenges in accessing healthcare

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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