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Microparticles show potential to deliver DNA-based vaccines and gene therapies in pill form

A microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln.

12 Apr 2017

Investigational device aims to minimize risk of cerebral damage during TAVR

One of the most common, and most serious, heart valve diseases is aortic stenosis. Left untreated, aortic stenosis gradually diminishes quality of life and leads to heart failure and death.

12 Apr 2017

Study shows new prospects for understanding mechanisms underlying vision

New approaches to the study of vision both from the neurobiological perspective and with a view to the technological development of artificial vision systems: that is the key result of the research project conducted by SISSA in Trieste in collaboration with the Istituto Italiano di Tecnologia in Rovereto and published in the science journal eLife.

12 Apr 2017

'Love hormone' could hold key to treating drug addicts, say experts

Experts say oxytocin, a key hormone made naturally by the brain, could hold the key to treating drug addicts and help them avoid relapse.

12 Apr 2017

Physical activity linked to better chances of survival after heart attack

Exercise is associated with improved survival after a heart attack, according to research published today in the European Journal of Preventive Cardiology. The chances of survival increased as the amount of exercise rose.

12 Apr 2017

Frequent hot flashes may be linked to increased heart disease risk

Hot flashes, one of the most common symptoms of menopause, have already been shown to interfere with a woman's overall quality of life.

12 Apr 2017

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation.

12 Apr 2017

Prevention, not cure, may be key to stopping Alzheimer’s disease

It has been 111 years since Auguste D. became the first person described with what is now called Alzheimer's disease.

12 Apr 2017

MUSC researchers provide first systemic evidence for safe use of tPA in stroke patients with SCD

Adult patients with sickle cell disease (SCD) who experience a stroke caused by a clot (i.e., ischemic strokes or IS) can be treated safely with tissue plasminogen activator (tPA) if they qualify, report investigators at the Medical University of South Carolina and elsewhere in the March 2017 issue of Stroke.

12 Apr 2017

Transmembrane protein complexes shed light on antibiotic resistance in bacteria

An international team including researchers from MIPT’s Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of the way bacteria process external signals.

12 Apr 2017

Study may provide insight into how R-LA promotes death of hepatoma cells

A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells.

12 Apr 2017

Public health approaches may need to be tailored based on diversity within Latinos, study suggests

Not all Latinos face the same health challenges, suggesting that public health approaches may need to be tailored based on needs of the diverse groups within the Latino population, new research from Oregon State University indicates.

12 Apr 2017

Research shows how language barriers, cultural differences disadvantage Latina breast cancer patients

The largest study to date of how Latina breast cancer patients evaluate treatment options highlights the need to counteract language barriers, information overload and a tendency to defer to rather than partner with doctors.

12 Apr 2017

Disability simulations do more harm than good, study reveals

Professionals in the fields of education and rehabilitation psychology have long used disability simulations to try to promote understanding and improve attitudes about persons with disabilities.

12 Apr 2017

Human Vaccines Project, VUMC and Illumina team up to decipher genetic underpinnings of immune system

The Human Vaccines Project and Vanderbilt University Medical Center (VUMC) today announced that they joined forces with Illumina, Inc., to decipher the human immunome, the genetic underpinnings of the immune system.

12 Apr 2017

Researchers explore patient adherence, tolerability to class of Alzheimer's drugs

Researchers from the Indiana University Center for Aging Research and the Regenstrief Institute have performed the first study conducted in the United States under real-world conditions comparing patient adherence and tolerability to a class of drugs known as cholinesterase inhibitors.

11 Apr 2017

Study explores health and function of cortical neurons in hand amputees

Researchers have found that the nerve cells (neurons) controlling sensation and movement of the hands show injury-induced changes for years after hand amputation, reattachment or transplant.

11 Apr 2017

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have found that the gene PID1 enhances killing of medulloblastoma and glioblastoma cells.

11 Apr 2017

TSRI scientists find new way to make cell population resistant to HIV

Scientists at The Scripps Research Institute have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus.

11 Apr 2017

Researchers use genetic manipulation to regenerate auditory hair cells in adult mice

In an apparent first, St. Jude Children's Research Hospital investigators have used genetic manipulation to regenerate auditory hair cells in adult mice. The research marks a possible advance in treatment of hearing loss in humans. The study appears today in the journal Cell Reports.

11 Apr 2017