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Genomic test effective for detecting Lynch syndrome in CRC patients

A single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than the traditional multiple, sequential testing approach, according to new clinical data reported by The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

29 Mar 2018

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth of cells in liver cancer.

29 Mar 2018

Ultra-slow waves in the brain directly linked to consciousness

If you keep a close eye on an MRI scan of the brain, you'll see a wave pass through the entire brain like a heartbeat once every few seconds. This ultra-slow rhythm was recognized decades ago, but no one quite knew what to make of it. MRI data are inherently noisy, so most researchers simply ignored the ultra-slow waves.

29 Mar 2018

Study shows limitations of AAV gene therapy in treating hereditary adrenal disorders

A new study has definitively shown that a single treatment with gene therapy using adeno-associated viral (AAV) vector gene delivery to replace the defective gene responsible for congenital adrenal hyperplasia (CAH) will only temporarily alleviate the hereditary disorder.

29 Mar 2018

Survey: Americans turn to foods, drinks, herbs and bedtime rituals to get a good night's sleep

A new survey from Sleep Cycle, the best-selling alarm clock application, reveals that Americans turn to a number of foods, drinks, herbs and bedtime rituals to get a good night's sleep.

29 Mar 2018

Infrastructure designed to encourage walking can help reduce childhood obesity

Children who live in more walkable neighborhoods have a smaller waist measurement and a lower BMI (body mass index). Those are the findings of a Montreal research team led by INRS professor Tracie A. Barnett. According to the results of the study published in Preventive Medicine by Adrian Ghenadenik (lead author) with Professor Barnett (senior contributing author), urban design is a factor in the development of childhood obesity.

29 Mar 2018

Topical solution may be less cytotoxic than cryosurgery for patients with seborrheic keratosis

Seborrheic keratosis is the most common noncancerous skin growth in adults seen by doctors in everyday practice.

29 Mar 2018

Tiny biochip holds promise for rapid and accurate disease detection

A novel invention by a team of researchers from the National University of Singapore (NUS) holds promise for a faster and cheaper way to diagnose diseases with high accuracy.

29 Mar 2018

New $3.2 million grant funds research to advance promising malaria vaccine

The Global Health Innovative Technology Fund has awarded the University of Florida and partners in the United States and Japan $3.2 million to advance a promising vaccine to prevent transmission of malaria.

29 Mar 2018

Researchers find expression of lymphatic markers in proliferative diabetic retinopathy tissues

Proliferative diabetic retinopathy is a major sight-threatening diabetic complication. Nearly all patients with type I diabetes and over 60% of patients with type II diabetes develop retinopathy after 20 years of diabetes, despite metabolic control.

29 Mar 2018

Effective pulmonary rehabilitation for persons with COPD in Germany

In Germany, 13.2% of the population older than 40 are affected by chronic obstructive pulmonary disease (COPD). By 2020, COPD will be the third most common cause of morbidity and mortality worldwide.

29 Mar 2018

Study provides broader picture of problems faced by stroke victims

A new study looks at what problems affect people most after a stroke and it provides a broader picture than what some may usually expect to see.

29 Mar 2018

Natural dietary supplement tends to improve blood pressure and arterial health

Scientists have long known that restricting calories can fend off physiological signs of aging, with studies in fruit flies, roundworms, rodents and even people showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan.

29 Mar 2018

Researchers develop novel approach to fighting ovarian cancer

Researchers have discovered a cellular pathway that selectively regulates a mutant protein linked to the growth of ovarian cancer.

29 Mar 2018

UTSW study reveals mechanisms underlying development of Sonic Hedgehog medulloblastoma

A delicate balance during brain development could have profound implications for understanding and treating medulloblastoma, the most common malignant brain tumor affecting children.

29 Mar 2018

Dining out may boost levels of health-harming phthalates in the body

Dining out more at restaurants, cafeterias and fast-food outlets may boost total levels of potentially health-harming chemicals called phthalates in the body, according to a study out today. Phthalates, a group of chemicals used in food packaging and processing materials, are known to disrupt hormones in humans and are linked to a long list of health problems.

29 Mar 2018

Study identifies potential genetic link in sudden infant death syndrome

Rare genetic mutations associated with impairment of the breathing muscles are more common in children who have died from sudden infant death syndrome (also known as ‘cot death’) than in healthy controls, suggesting a possible genetic element of the disorder, according to a case-control study in the UK and USA published in The Lancet.

29 Mar 2018

Pitt scientists develop new emergency and trauma care referral map to improve health care quality

In response to repeated calls for an integrated and coordinated emergency and trauma care system in the U.S., University of Pittsburgh School of Medicine scientists and UPMC physicians rose to the challenge and divided the nation into hundreds of referral regions that describe how patients access advanced care, in a way that respects geopolitical borders.

29 Mar 2018

Thrill of hockey victory may raise heart attack risk in younger men

The thrill of a hockey victory may put younger men at an increased risk for heart attack. A new study published in the Canadian Journal of Cardiology found an increase in hospital admissions for men under 55 presenting with symptoms of ST-elevation myocardial infarction or heart attack the day after a Montreal Canadiens win.

29 Mar 2018

Single high-fat meal can set the stage for cardiovascular disease

A single high-fat milkshake, with a fat and calorie content similar to some enticing restaurant fare, can quickly transform our healthy red blood cells into small, spiky cells that wreak havoc inside our blood vessels and help set the perfect stage for cardiovascular disease, scientists report.

29 Mar 2018