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Triple therapy reduces tumor burden and improves survival in glioblastoma models

A new research paper was published in Oncotarget, Volume 16, on March 27, 2025, titled "Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT."

4 Apr 2025

CRISPR tool unveils genetic drivers of blood cell maturation

Collaborative research led by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation.

4 Apr 2025

Cornell researchers discover brain mechanisms behind psilocybin's effects

Psilocybin is the active ingredient that gives so-called "magic mushrooms" their hallucinogenic kick. It also has a therapeutic potential for treating depression.

4 Apr 2025

New study reveals hidden spread of C. diff in intensive care units

One of the most common health care-associated infections spreads within intensive care units (ICUs) more than three times more than previously thought, new research has found.

4 Apr 2025

Pancreatic cells show epigenetic marks before cancerous transformation

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

4 Apr 2025

Small molecular shifts can drastically alter encephalitis virus behavior

New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts could turn a deadly pathogen into a harmless bug or supercharge a relatively benign virus, influencing its ability to infect humans and cause dangerous outbreaks.

4 Apr 2025

Exposure to wildfire smoke raises mental health visits to emergency departments

Exposure to fine particulate air pollution (PM2.5) from wildfire smoke was associated with increased visits to emergency departments (ED) for mental health conditions, according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

4 Apr 2025

Uncommon ovarian tumors detected in a single patient

A new case report was published in Oncoscience's Volume 12 on March 31, 2025, titled "Cystadenofibroma and contralateral collision lesions: A unique ovarian case report."

4 Apr 2025

Cedars-Sinai study reveals distinct roles for AI and physicians in virtual care

Do physicians or artificial intelligence (AI) offer better treatment recommendations for patients examined through a virtual urgent care setting? A new Cedars-Sinai study shows physicians and AI models have distinct strengths.

4 Apr 2025

Two plant-based diets linked to similar survival benefits and low environmental impact

Two plant-based diets were associated with similar survival benefits and low environmental impact, according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

4 Apr 2025

New insights into bacterial defense mechanisms could help combat antibiotic resistance

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades.

4 Apr 2025

Early warning signs may help prevent sudden arrhythmic death syndrome

Recognizing and detecting the signs that commonly precede sudden arrhythmic death syndrome (SADS) may help to prevent premature deaths, according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

4 Apr 2025

Women with pre-eclampsia face early onset of cardiovascular risk factors

Women who have experienced pre-eclampsia have accelerated accumulation of cardiovascular (CV) risk factors compared with women who had pregnancies without pre-eclampsia according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

4 Apr 2025

Swedish study highlights prevalence of fetal alcohol spectrum disorders

Out of 206 fourth-grade students, 19 met criteria for fetal alcohol spectrum disorders. This was found in a pilot study conducted at the University of Gothenburg.

4 Apr 2025

Innovative oral vaccine strategy combats intestinal pathogens

The issue of intestinal bacteria is a complex one. On the one hand, we are dependent on the microorganisms because they are the ones that digest the food in our intestine.

4 Apr 2025

Study links outdoor time and multisport to improved motor skills in children

A study conducted by the Faculty of Sport and Health Sciences at the University of Jyväskylä followed the development of children's motor skills over a three-year period, from early childhood education to school age.

4 Apr 2025

Your phone might be the reason you can’t sleep

Researchers investigate whether screen use in bed, particularly social media use, affects sleep as compared to other screen-based activities in students.

4 Apr 2025

Over 250 million people worldwide unaware they have diabetes, according to new research from the International Diabetes Federation (IDF)

Globally, nearly one in nine adults (589 million) are now living with diabetes. Of these, an estimated 252 million are not yet aware they have the condition, placing them at higher risk of serious complications and early death.

4 Apr 2025

Hormonal contraceptives linked to higher postpartum depression risk

Researchers investigate whether the use of hormonal contraception increases the risk of postpartum depression.

4 Apr 2025

European study reveals stabilization patterns in antibiotic resistance

Antibiotic resistance tends to stabilize over time, according to a study published April 3, 2025 in the open-access journal PLOS Pathogens by Sonja Lehtinen from the University of Lausanne, Switzerland, and colleagues.

4 Apr 2025