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Gut bacteria may reduce the effectiveness of common medications

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

3 Apr 2025

Switching to a Western diet triggers inflammation and weakens immunity

A switch of just two weeks from a traditional African diet to a Western diet causes inflammation, reduces the immune response to pathogens, and activates processes associated with lifestyle diseases.

3 Apr 2025

Low walkability in neighborhoods associated with higher heart disease risk

Low neighborhood walkability is associated with increased risk of cardiovascular disease (CVD), according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

3 Apr 2025

Heart failure linked to faster cognitive decline

There are over six million Americans with heart failure who are at greater risk of losing their cognitive abilities earlier in life, a study suggests.

3 Apr 2025

Late-starters in vaping reach high usage levels more rapidly

A new study has found that young vapers in the United States who begin using e-cigarettes after graduating from secondary/high school are likely to progress rapidly to frequent use.

3 Apr 2025

Penn Medicine CAREs grants support patient storytelling and community health

Hospitals, some of the busiest places, can also be among the loneliest.

3 Apr 2025

NUZ-001 shows positive results in human 3D brain model

Neurizon Therapeutics Limited (“Neurizon”), a clinical-stage biotech company dedicated to advancing treatments for neurodegenerative diseases, is pleased to advise that results from an independent study undertaken in collaboration with Tessara Therapeutics (“Tessara”) will be presented by the group’s Principal Scientist and Alzheimer’s Disease expert, Dr Mark Greenough at the AD/PD 2025 Advances in Sciences & Therapy conference on April 2nd to 3rd.

3 Apr 2025

New data on use of EndoZip™ to treat obese patients be presented at leading global medical conferences

Nitinotes, developer of EndoZip™, a fully automated endoscopic suturing system aimed at treating obesity, today announced that clinical research on the EndoZip™ system will be presented at upcoming leading international medical conferences.

3 Apr 2025

Study exposes huge levels untargeted antibiotic prescribing

Doctors are prescribing antibiotics for tens of thousands of patients with infections, with little or no consideration of prognosis and the risk of the infection worsening, according to a new study led by University of Manchester epidemiologists.

3 Apr 2025

Dutch dietary guidelines could dramatically cut chronic disease rates by 2050

Researchers investigate the impact of current Dutch dietary guidelines on non-communicable disease rates.

3 Apr 2025

Addressing low lung cancer screening rates through awareness and access

Lung cancer screening has the potential to catch lung cancer early and save lives-but only if people get screened. Although lung cancer screening is recommended in the U.S. for certain individuals with a history of smoking, only 18% of eligible individuals in the U.S. get screened.

3 Apr 2025

New cystic fibrosis newborn screening guidelines aim for equitable detection

The United States Cystic Fibrosis Foundation released the first guideline on newborn screening for cystic fibrosis (CF), in order to improve timely detection of CF in infants from all racial and ethnic backgrounds.

3 Apr 2025

Mouse and organoid models reveal FGFR2's role in pancreatic cancer aggression and interception

Pancreatic cancer is projected to become the second-deadliest cancer by 2030. By the time it's diagnosed, it's often difficult to treat. So, for both individual patients and the general population, fighting pancreatic cancer can feel like a race against time. Cold Spring Harbor Laboratory (CSHL) Professor and Cancer Center Director David Tuveson offers a telling analogy:

3 Apr 2025

Unraveling resistance to CDK4/6 inhibitors in ovarian cancer

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies.

3 Apr 2025

Racial and age disparities in cervical artery dissection hospitalizations

Cervical artery dissection is a tear in an artery in the neck that provides blood flow to the brain. Such a tear can result in blood clots that cause stroke. A new study has found almost a five-fold increase in the number of U.S. hospitalizations for cervical artery dissection over a 15-year period.

3 Apr 2025

New structural and mechanistic understanding for cancer drug design

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and mechanistic understanding of the RAD52-DNA complex may help researchers develop new anti-cancer drugs.

3 Apr 2025

New research underscores the importance of broader health benefits in obesity care

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) suggests that weight loss program targeting a particular % weight loss are often failing, and that other factors should be considered including improvement of obesity-related complications, enhancing quality of life and overall physical and social functioning.

3 Apr 2025

Neuropathological basis of visual dysfunction in rare Alzheimer's forms

Differences in the distribution of certain proteins and markers in the brain may explain why some people first experience vision changes instead of memory loss in Alzheimer's disease, finds a new study by UCL researchers.

3 Apr 2025

Healthcare affordability crisis in the U.S. reaches a new high

The inability to pay for healthcare in the U.S. has reached a new high, with more than one-third of Americans (35%), or an estimated 91 million people, reporting that they could not access quality healthcare if they needed it today, according to the latest West Health-Gallup Healthcare Affordability Index.

2 Apr 2025

Exploring the relationship between testosterone and men's health

The review article titled"Testosterone and men's health: An in-depth exploration of their relationship", was published on February 18, 2025 in UroPrecision.

2 Apr 2025