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Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

9 Nov 2017

3D cultured spheroids could drive precision treatment for ovarian cancer

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

9 Nov 2017

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

An analysis of the medical records of patients treated at Massachusetts General Hospital (MGH) for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that some cases are caused by autoimmune disease and also identifies the first effective treatment option.

9 Nov 2017

Experimental ‘golden’ potato could hold power to prevent disease in developing nations

An experimental "golden" potato could hold the power to prevent disease and death in developing countries where residents rely heavily upon the starchy food for sustenance, new research suggests.

9 Nov 2017

Researchers catch killer cells red-handed in the act of microbial murder

Immune cells called "killer cells" target bacteria invading the body's cells, but how do they do this so effectively? Bacteria can quickly evolve resistance against antibiotics, yet it seems they have not so readily been able to evade killer cells. This has caused researchers to become interested in finding out the exact mechanism that killer cells use to destroy bacterial invaders.

9 Nov 2017

Video provides new look at natural process of platelet-driven blood clot contraction

The first view of the physical mechanism of how a blood clot contracts at the level of individual platelets is giving researchers from the Perelman School of Medicine at the University of Pennsylvania a new look at a natural process that is part of blood clotting.

9 Nov 2017

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

The Center for Applied NanoBioscience and Medicine is doing its part to protect the health of astronauts on long-duration missions, including NASA's Journey to Mars.

9 Nov 2017

Antiviral drug selectively targets the most aggressive viruses, research says

An antiviral drug that inhibits a virus' replication machinery selectively targets the most aggressive viruses, according to new research that looked at the infection of individual cells by a virus and the consequence of antiviral intervention.

9 Nov 2017

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago found a way to improve the drugs' impact while limiting treatment-related side effects.

9 Nov 2017

Study examines fall prevention program designed to help aging adults

Two NDSU researchers have published a paper giving high marks to a program designed to help aging adults prevent falls.

9 Nov 2017

Research suggests link between heart function and brain region critical for memory processing

Research by a team of Vanderbilt University Medical Center scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer's pathology first begins.

9 Nov 2017

Women with ER-positive breast cancer face disease recurrence risk years after treatment ends

Even 20 years after a diagnosis, women with a type of breast cancer fueled by estrogen still face a substantial risk of cancer returning or spreading, according to a new analysis from an international team of investigators published in the New England Journal of Medicine.

9 Nov 2017

Injection of nanoparticles could divert immune cells that cause inflammation

A surprise finding suggests that an injection of nanoparticles may be able to help fight the immune system when it goes haywire, researchers at the University of Michigan have shown. The nanoparticles divert immune cells that cause inflammation away from an injury site.

9 Nov 2017

Scientists uncover mechanism that prevents tumor growth in melanoma

Natural Killer (NK) cells, lymphocytes of the innate immune system with strong cytotoxic activity, play a major role in the immune response against tumors.

8 Nov 2017

Intrauterine devices (IUDs) may lower risk of cervical cancer

According to a recent study, intrauterine devices (IUDs) used by women for contraception might lower the risk of getting cervix cancer compared to women who do not use this form of contraception. The review titled, “Intrauterine Device Use and Cervical Cancer Risk: A Systematic Review and Meta-analysis” from the Keck School of Medicine of USC appeared in the online November issue of Obstetrics & Gynecology.

8 Nov 2017

Human brain organoids in the making amidst ethical concerns

Scientists from Vienna have worked for four years and finally come up with a small blob of human brain tissue that has been created from stem cells. These human brain organoids as they are called, are capable of pulsing with electrical activity and also create new nerve cells or neurons.

8 Nov 2017

Complete new skin from transgenic stem cells for boy with rare genetic disease

Hassan, a then seven-year-old boy from Germany, in 2015, presented to the doctors with a rare skin disease called junctional epidermolysis bullosa or JEB. This condition leaves the skin thin and papery and easily breakable. It has been compared to “butterfly wings” because of their fragile nature.

8 Nov 2017

Researchers discover mechanism behind skin inflammation in eczema

Publishing online this week in Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key underlying immune mechanism that explains why to how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema. Toxin-producing bacteria on the surface of our skin induces a protein that causes our own cells to react and cause inflammation.

8 Nov 2017

Scientists uncover previously unknown mechanism to combat influenza A virus

Just as flu season swings into full gear, researchers from the University of Colorado Boulder and University of Texas at Austin have uncovered a previously unknown mechanism by which the human immune system tries to battle the influenza A virus.

8 Nov 2017

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside cancer cells in laboratory cultures.

8 Nov 2017

Medical Research News

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

3D cultured spheroids could drive precision treatment for ovarian cancer

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

Experimental ‘golden’ potato could hold power to prevent disease in developing nations

Researchers catch killer cells red-handed in the act of microbial murder

Video provides new look at natural process of platelet-driven blood clot contraction

UA researchers receive grant to study effects of simulated space radiation on gastrointestinal tract

Antiviral drug selectively targets the most aggressive viruses, research says

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

Study examines fall prevention program designed to help aging adults

Research suggests link between heart function and brain region critical for memory processing

Women with ER-positive breast cancer face disease recurrence risk years after treatment ends

Injection of nanoparticles could divert immune cells that cause inflammation

Scientists uncover mechanism that prevents tumor growth in melanoma

Intrauterine devices (IUDs) may lower risk of cervical cancer

Human brain organoids in the making amidst ethical concerns

Complete new skin from transgenic stem cells for boy with rare genetic disease

Researchers discover mechanism behind skin inflammation in eczema

Scientists uncover previously unknown mechanism to combat influenza A virus

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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