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Rochester scientists identify stem cells capable of skull formation, craniofacial bone repair in mice

A team of Rochester scientists has, for the first time, identified and isolated a stem cell population capable of skull formation and craniofacial bone repair in mice--achieving an important step toward using stem cells for bone reconstruction of the face and head in the future, according to a new paper in Nature Communications.

1 Feb 2016

Women who eat more high-fiber foods during young adulthood may have lower breast cancer risk

Women who eat more high-fiber foods during adolescence and young adulthood--especially lots of fruits and vegetables--may have significantly lower breast cancer risk than those who eat less dietary fiber when young, according to a new large-scale study led by researchers at Harvard T.H. Chan School of Public Health.

1 Feb 2016

Frequent consumption of nuts may reduce risk of breast, colon, pancreatic and lung cancer

Adding nuts to your diet is associated to a reduction in the risk of cancer. This is the main conclusion of multiple studies that have shown that eating 2 or 3 servings per week (57-84 g) of nuts is associated to a reduction in the risk of some types of cancer (breast, colon, pancreatic and lung cancer).

1 Feb 2016

MabVax receives FDA authorization to initiate 89Zr-HuMab-5B1 Phase I trial in pancreatic cancer patients

MabVax Therapeutics Holdings, Inc., a clinical-stage oncology drug-development company, announces receipt of notice from the U.S. Food and Drug Administration authorizing initiation of a Phase I clinical trial with 89Zr-HuMab-5B1 as a new generation PET scan cancer imaging agent in patients with pancreatic cancer.

1 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

Researchers show how bacterial colony protects itself against toxic substances

Bacterial populations move over surfaces in coordinated way known as swarming, which allows them to spread further over organs and tissues and increases the virulence of the infection. This movement is driven by the action of the flagella and the chemoreceptors, the systems responsible for identifying chemical compounds in the environment and which are anchored at the poles of their cells, forming highly organised structures, of which the protein CheW forms part.

1 Feb 2016

Physically fit individuals' maximal heart rate decline at slower rate with age

Cardiovascular disease remains the number one cause of death. It is well known that being physically fit is associated with lower risk of disease. One factor associated with higher risk of cardiovascular disease is having a low maximal heart rate.

1 Feb 2016

New technology could help identify, characterize biologically active molecules produced by living cells

Gene sequencing company Illumina recently made big waves by announcing a new spinoff, Grail, dedicated to building a test for cancer by sequencing tumor DNA fragments found in blood. The company also reported plans for a separate project to identify single cells and tag them for later analysis.

1 Feb 2016

Cherry-flavoured e-cigarette users may be exposed to potentially harmful chemical

An analysis of 145 different electronic-cigarette flavoring products reveals that many e-cigarette users may be exposed to a potentially harmful chemical. In a research letter published online today in the peer-reviewed journal Thorax, a research team led by Maciej Goniewicz, PhD, PharmD, of Roswell Park Cancer Institute reports that high levels of the respiratory irritant benzaldehyde were detected in the vapor from most of the flavored nicotine products they studied, with the highest concentrations in vapor from cherry-flavored products.

1 Feb 2016

New UEA-led research initiative aims to improve understanding of deictic communication in humans

A major new €3.5 million research initiative led by the University of East Anglia will aim to improve understanding of a fundamental part of communication in humans.

1 Feb 2016

Researchers link symptoms of schizophrenia with the brain's anatomical characteristics

An international team, made up of researchers from the University of Granada, Washington University in St. Louis, and the University of South Florida, has linked the symptoms of schizophrenia with the anatomical characteristics of the brain, by employing magnetic resonance imaging (MRI).

1 Feb 2016

Frequent traumatic experiences throughout infancy increase risk of psychosis during adulthood

A research carried out with participation of the University of Granada proves that suffering repeated traumatic experiences throughout infancy and adolescence multiplies by 7 the risk of suffering psychosis during adulthood.

1 Feb 2016

Proton beam therapy safe for treating childhood brain cancer medulloblastoma

Proton beam therapy--a more precise form of radiotherapy--to treat the childhood brain cancer medulloblastoma appears to be as safe as conventional radiotherapy with similar survival rates, according to new research published in The Lancet Oncology journal today.

1 Feb 2016

New brain study affirms truth in age old theory 'practice makes perfect'

'Practice makes perfect' may be a cliché but a new brain study out of York U affirms this age old theory. In this study, Faculty of Health researchers were looking at fMRI brain scans of professional ballet dancers to measure the long-term effects of learning.

1 Feb 2016

Newcastle University scientists use seaweed extract to develop 'Stem-gell' bandage for wound healing

Publishing in STEM CELLS Translational Medicine Professor Che Connon and Dr Stephen Swioklo describe the low-cost seaweed solution.

1 Feb 2016

Research offers novel insights into root causes of schizophrenia

Schizophrenia is a mysterious and devastating disorder that afflicts one percent of the adult population worldwide. Its symptoms — hallucinations, emotional withdrawal, and cognitive impairment — are chronic and typically emerge just as individuals are entering adulthood. Today's medications treat just one of these symptoms (psychosis); treatments for the underlying disease and its many other symptoms have been hard to develop, because no one really understands what causes the disorder.

31 Jan 2016

Bile acid enables foetus to produce blood stem cells

A research group at Lund University in Sweden has been able to show that bile acid is transferred from the mother to the foetus via the placenta to enable the foetus to produce blood stem cells.

31 Jan 2016

Framework for improving chemical hazard assessment without animals

A new paper published in Regulatory Toxicology and Pharmacology, co-authored by the Physicians Committee for Responsible Medicine, calls for ongoing development and regulatory acceptance of adverse outcome pathways (AOPs), a framework for improving chemical hazard assessment by prioritizing modern test methods that reduce animal use.

31 Jan 2016

Study provides vital information about mechanisms governing DNA repair

DNA damage can lead to gene inactivation or deregulation and cause various diseases such as cancer; however, many DNA repair mechanisms allow cells to survive against such damage. A study lead by Antoine Simoneau of the laboratory of Dr. Hugo Wurtele, a researcher in immunology-oncology at the Maisonneuve-Rosemont Hospital (CIUSS de l'Est-de-l'Île-de-Montréal) and professor at the Faculty of Medicine, University of Montreal, and recently published in the prestigious journal Nucleic Acids Research, provides valuable information about certain mechanisms governing DNA repair.

31 Jan 2016

SLU clinical psychologist helps patients battle fears, phobias

Some fear is rational, keeping us appropriately cautious in the face of dangerous animals, hot stoves and contagions that could make us ill. But rational caution can turn to irrational panic about imagined terrors that are unlikely to occur or cause much actual damage if they did.

31 Jan 2016

Medical Research News

Rochester scientists identify stem cells capable of skull formation, craniofacial bone repair in mice

Women who eat more high-fiber foods during young adulthood may have lower breast cancer risk

Frequent consumption of nuts may reduce risk of breast, colon, pancreatic and lung cancer

MabVax receives FDA authorization to initiate 89Zr-HuMab-5B1 Phase I trial in pancreatic cancer patients

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

Researchers show how bacterial colony protects itself against toxic substances

Physically fit individuals' maximal heart rate decline at slower rate with age

New technology could help identify, characterize biologically active molecules produced by living cells

Cherry-flavoured e-cigarette users may be exposed to potentially harmful chemical

New UEA-led research initiative aims to improve understanding of deictic communication in humans

Researchers link symptoms of schizophrenia with the brain's anatomical characteristics

Frequent traumatic experiences throughout infancy increase risk of psychosis during adulthood

Proton beam therapy safe for treating childhood brain cancer medulloblastoma

New brain study affirms truth in age old theory 'practice makes perfect'

Newcastle University scientists use seaweed extract to develop 'Stem-gell' bandage for wound healing

Research offers novel insights into root causes of schizophrenia

Bile acid enables foetus to produce blood stem cells

Framework for improving chemical hazard assessment without animals

Study provides vital information about mechanisms governing DNA repair

SLU clinical psychologist helps patients battle fears, phobias

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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