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Researchers identify molecular patterns that dominate gene expression in the human brain

The human brain may be the most complex piece of organized matter in the known universe, but Allen Institute researchers have begun to unravel the genetic code underlying its function. Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

CRI scientists identify emergency blood-formation system inside the body

Scientists at the Children's Medical Center Research Institute at UT Southwestern have determined how the body responds during times of emergency when it needs more blood cells. In a study published in Nature, researchers report that when tissue damage occurs, in times of excessive bleeding, or during pregnancy, a secondary, emergency blood-formation system is activated in the spleen.

17 Nov 2015

Overweight men also experience interpersonal discrimination just like overweight women

Men who are overweight are just as likely as overweight women to experience interpersonal discrimination when applying for a job or shopping at retail stores, according to new research from Rice University and the University of North Carolina, Charlotte.

17 Nov 2015

Researchers identify new target for novel immune-oncology treatments

By studying a type of immune cells, a team of researchers at the IRCM led by André Veillette, MD, identified the mechanism of action for a new target for novel immune-oncology treatments. Their discovery is published today in the print edition of the scientific journal the Journal of Experimental Medicine.

17 Nov 2015

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

University of Cincinnati researchers have discovered the negative impact a high fat diet has on red blood cells and how these cells, in turn, promote the development of cardiovascular disease.

17 Nov 2015

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long-term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

17 Nov 2015

New analysis points to use of e-cigarettes as quitting aid among U.S. adults

Adding to a growing body of research on patterns of e-cigarette use, researchers from Rutgers School of Public Health and the Steven A. Schroeder Institute for Tobacco Research and Policy Studies at Truth Initiative have found evidence that among U.S. adults, some recent cigarette quitters may have done so with the assistance of electronic cigarettes.

17 Nov 2015

New US bipartisan study advocates promoting global health to advance wide range of American interests

A new US bipartisan study advocates promoting global health to both "do the right thing" and advance wide-ranging foreign policy interests.

17 Nov 2015

Tobacco use continues to be a top threat to health and economic well-being of people in China

Efforts over the past seven years to reduce tobacco use in China have been strikingly ineffective and leave tobacco use a top threat to the health and economic well-being of the world's largest country, according to research findings by the University of Waterloo's International Tobacco Control Policy Evaluation Project (ITC Project).

17 Nov 2015

Children in low-income families have greater access to preventive care under Medicaid, CHIP

Researchers have found that children in low-income families experience greater access to preventive medical and dental care under Medicaid or the Children's Health Insurance Program (CHIP) than children covered by private insurance. However, for all types of insurance coverage, access to pediatric specialty care was a challenge.

17 Nov 2015

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Researchers at the University of Arizona have invented a device that for the first time allows neurosurgeons, who use microscopes extensively while operating, to see blood flowing inside vessels and more clearly distinguish cancerous from healthy tissue under the microscope.

17 Nov 2015

Health care costs for Alzheimer's disease patients increase a year before diagnosis

The health care costs of patients diagnosed with Alzheimer's disease (AD) start to increase already one year before the diagnosis, shows a new study from the University of Eastern Finland.

17 Nov 2015

Improved gene therapy treatment shows promise in mice with cystic fibrosis

An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment. Those are the encouraging results of a study presented by the Laboratory for Molecular Virology and Gene Therapy at KU Leuven, Belgium.

17 Nov 2015

Study finds that living liver donors highly satisfied with donation process

A study of living liver donors found donors were highly satisfied with the donation process. Findings published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases, indicate most donors would donate again, independent of any complications from transplantation.

17 Nov 2015

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Support comes out of the ground: Scientists from the Helmholtz Centre for Infection Research in Germany have identified a terrestrial myxobacterium as a promising source for the bengamide class of natural products, which were originally thought to be secondary metabolites of marine sponges only.

17 Nov 2015

Escalation therapy for neuromyelitis attacks improves remission rates

Researchers recommend escalating patients’ therapy in the event of continuing attacks of neuromyelitis optica, basing sequential treatment on the type of attack and prior treatment response.

16 Nov 2015

Haemodynamic variables may distinguish pre- from post-capillary PH

Researchers have identified the haemodynamic variables that best distinguish between patients with idiopathic pulmonary arterial hypertension and isolated post-capillary pulmonary hypertension.

16 Nov 2015

MedUni Vienna researchers discover genetic cause of a rare disease

Researchers at MedUni Vienna have discovered the genetic cause of a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when they reach school age.

15 Nov 2015

Research collaboration aims to develop new drug for slow-healing chronic wounds

The biotech company Omnio based in Swedish Umeå, and led by researcher Tor Ny at Umeå University, launches a research collaboration with the Canadian pharmaceutical company ProMetic to develop a new drug for slow-healing chronic wounds. The collaboration includes funding for clinical studies of a drug based on the blood plasma protein plasminogen.

15 Nov 2015

Medical Research News

Researchers identify molecular patterns that dominate gene expression in the human brain

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

CRI scientists identify emergency blood-formation system inside the body

Overweight men also experience interpersonal discrimination just like overweight women

Researchers identify new target for novel immune-oncology treatments

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

New analysis points to use of e-cigarettes as quitting aid among U.S. adults

New US bipartisan study advocates promoting global health to advance wide range of American interests

Tobacco use continues to be a top threat to health and economic well-being of people in China

Children in low-income families have greater access to preventive care under Medicaid, CHIP

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Health care costs for Alzheimer's disease patients increase a year before diagnosis

Improved gene therapy treatment shows promise in mice with cystic fibrosis

Study finds that living liver donors highly satisfied with donation process

Helmholtz Centre for Infection Research scientists identify promising antitumor agent

Escalation therapy for neuromyelitis attacks improves remission rates

Haemodynamic variables may distinguish pre- from post-capillary PH

MedUni Vienna researchers discover genetic cause of a rare disease

Research collaboration aims to develop new drug for slow-healing chronic wounds

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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