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Discovery of signaling pathway offers new functional framework for treating schizophrenia

Neuroscientists at Tufts University School of Medicine have discovered a new signaling pathway that directly connects two major receptors in the brain associated with learning and memory – the N-methyl-D-aspartate receptor (NMDAR) and the alpha 7 nicotinic acetylcholine receptor (a7nAChR) – which has significance for current efforts to develop drugs to treat schizophrenia.

4 May 2017

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. This mortality gap – driven by social and environmental, as well as biological factors – continues to persist.

4 May 2017

Long periods of physiological stress can change composition of intestinal microbiota in soldiers

A new study finds that long periods of physiological stress can change the composition of microorganisms residing in the intestines, which could increase health risks in endurance athletes and military personnel.

4 May 2017

Research examines impact of language barriers on patient outcomes in home health care

In the United States, one in every five households speaks a language other than English at home. Research has shown, as English language proficiency decreases, positive healthcare outcomes also decrease.

4 May 2017

Survey provides important data on lasting impact of incarceration on older Americans’ lives

Americans age 50 and older who report that they have been incarcerated at some point in their lives are more likely to express anxiety about several aspects of retirement, to have experienced unemployment in the recent past, and to have fewer sources of income for retirement than those who have not, according to a new national survey of Americans age 50 and older from The Associated Press-NORC Center for Public Affairs Research.

4 May 2017

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Columbia University Medical Center researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy.

4 May 2017

Baby rice food products contain illegal levels of inorganic arsenic, research finds

In January 2016, the EU imposed a maximum limit of inorganic arsenic on manufacturers in a bid to mitigate associated health risks. Researchers at the Institute for Global Food Security at Queen's have found that little has changed since this law was passed and that 50 percent of baby rice food products still contain an illegal level of inorganic arsenic.

4 May 2017

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Among scientists specializing in the area, the mechanisms behind the signaling function of the Hedgehog (Hh) receptor pathway remain a mystery. Xiaoyen Zheng, Ph.D., assistant professor of anatomy and regenerative biology at the George Washington University School of Medicine and Health Sciences, who recently received a $1.7 million grant from the National Institutes of Health and National Institute of General Medical Sciences, is determined to learn more about the Hh pathway.

4 May 2017

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Researchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic influences that may offer clues to more accurate diagnosis and treatment.

4 May 2017

Breast-feeding may aid development of white matter structures in the brains of premature babies

To the growing list of reasons why mothers should consider breast-feeding infants, add another: Critical white matter structures in the brains of babies who are born so prematurely that they weigh less than 1,500 grams develop more robustly when their mothers breast-feed them, compared with preemie peers who are fed formula.

4 May 2017

International consensus addresses research bottlenecks to diagnose rare genetic diseases

A worldwide consensus co-authored by more than 40 scientists sets out ways to address research bottlenecks as the international community strives to diagnose most rare genetic diseases by 2020.

4 May 2017

New synthetic retina could offer new hope to visually impaired people

A synthetic, soft tissue retina developed by an Oxford University student could offer fresh hope to visually impaired people.

4 May 2017

Study finds higher rates of suicidal thoughts and attempts among transgender adults

Suicidal thoughts and attempts by adult transgender individuals were 14 and 22 times higher, respectively, than rates for the general public, according to a new study published in Transgender Health, a peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers. The article is available open access on the Transgender Health website.

4 May 2017

Children with single-ventricle disease have higher rates of brain abnormalities at each stage of surgery

As children with single-ventricle disease, a complex and severe heart defect, undergo a series of three reconstructive surgeries, pediatric researchers have detected higher rates of brain abnormalities at each stage.

4 May 2017

American Cancer Society awards new $792,000 grant to Yale researcher

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding of a new research grant totaling $792,000 to a researcher at Yale University.

4 May 2017

Scientists identify differences in outcomes for women and men with AFF in emergency departments

Atrial fibrillation and flutter (also known as AFF) is associated with serious health problems and is a significant contributor to death rates.

4 May 2017

Researchers develop hybrid nanomaterial for destruction of cancer cells

Most tumors contain regions of low oxygen concentration where cancer therapies based on the action of reactive oxygen species are ineffective.

4 May 2017

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Men and women differ in obvious and less obvious ways -- for example, in the prevalence of certain diseases or reactions to drugs. How are these connected to one's sex? Weizmann Institute of Science researchers recently uncovered thousands of human genes that are expressed -- copied out to make proteins -- differently in the two sexes.

4 May 2017

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

Researchers at Baylor College of Medicine have discovered that changing the circadian clock in mouse liver can alter how the body responds to diet and also change the microbes living in the digestive track.

4 May 2017

Newly-developed smart contact lens sensor may help diagnose diabetes and glaucoma

A recent study, affiliated with UNIST has proposed the possibility of in situ human health monitoring simply by wearing a contact lens with built-in wireless smart sensors.

4 May 2017

Medical Research News

Discovery of signaling pathway offers new functional framework for treating schizophrenia

Genetic study outlines path to personalize breast cancer risk assessment and treatment

Long periods of physiological stress can change composition of intestinal microbiota in soldiers

Research examines impact of language barriers on patient outcomes in home health care

Survey provides important data on lasting impact of incarceration on older Americans’ lives

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Baby rice food products contain illegal levels of inorganic arsenic, research finds

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Genetic findings may offer clues to accurate diagnosis and treatment of type 1.5 diabetes

Breast-feeding may aid development of white matter structures in the brains of premature babies

International consensus addresses research bottlenecks to diagnose rare genetic diseases

New synthetic retina could offer new hope to visually impaired people

Study finds higher rates of suicidal thoughts and attempts among transgender adults

Children with single-ventricle disease have higher rates of brain abnormalities at each stage of surgery

American Cancer Society awards new $792,000 grant to Yale researcher

Scientists identify differences in outcomes for women and men with AFF in emergency departments

Researchers develop hybrid nanomaterial for destruction of cancer cells

Scientists uncover thousands of human genes that are expressed differently in the two sexes

Disrupting the circadian clock can alter gut microbiome and the body's response to diet

Newly-developed smart contact lens sensor may help diagnose diabetes and glaucoma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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