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New technique helps study protein changes in brain tissue of Alzheimer's patients

Using 10-year-old archival brain tissue from patients with Alzheimer's disease, a research team from NYU Langone Medical Center has developed a novel method to examine the structure and function of proteins at the cell level -- providing greater means to study protein changes found in Alzheimer's disease.

23 Oct 2015

Study shows promise for developing targeted treatments for multiple sclerosis

Modern scientific understanding has considered multiple sclerosis (MS) to be a disease controlled by the T cell, a type of white blood cell. Research has shown that in MS, T cells inappropriately attack myelin, the protective layer of fat covering nerves in the central nervous system, exposing them to damage.

23 Oct 2015

Chronic diseases increased dramatically among poorest households in Bangladesh, suggests new research

The number of people in Bangladesh dying from chronic diseases such as cancer, diabetes and hypertension—long considered diseases of the wealthy because the poor didn't tend to live long enough to develop them—increased dramatically among the nation's poorest households over a 24-year period, suggests new research from the Johns Hopkins Bloomberg School of Public Health.

23 Oct 2015

Juneau Biosciences presents new genetic discoveries in endometriosis at annual ASRM meeting

This week, Juneau Biosciences, LLC presented new discoveries concerning the genetics of endometriosis at the annual American Society of Reproductive Medicine (ASRM) meeting in Baltimore, MD.

23 Oct 2015

Smartphone app may improve self-management skills in young patients with spina bifida

A system incorporating a smartphone app may help adolescents and young adults with spina bifida to improve their daily self-management skills, suggests a paper in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. The journal is published by Wolters Kluwer.

23 Oct 2015

Findings suggest a potential "early warning" detection system for Alzheimer's disease

The findings suggest a potential "early warning" detection system for Alzheimer's disease, even in young and asymptomatic individuals.

23 Oct 2015

Biological sensor protein could help combat diabetes, obesity

In the study, researchers showed a protein called NLRP1 is switched on when increased dietary energy (food) intake triggers the cell to become 'unstable'.

23 Oct 2015

DNA study reveals basic principle of gene regulation

A study of where and how an enzyme cuts DNA may have inadvertently revealed a basic principle of gene regulation, say researchers in Boston Children's Hospital's Program in Cellular and Molecular Medicine (PCMM).

23 Oct 2015

Cochlear implants improve outcomes in infants with profound hearing loss

'Dada' is a first word for many babies. Babbling sounds with consonant-vowel repetitions, such as 'dada,' are common among infants once they reach 8 months old; however, these sounds are not prevalent among infants who have profound hearing loss -- that is, until they receive cochlear implants.

23 Oct 2015

Early trial results in lung cancer

Results from early phase trials investigating different therapeutic agents in lung cancer patients were presented during the third Presidential Session at the European Cancer Congress in Vienna, Austria. Here we summarise two studies reported at the session.

22 Oct 2015

Culprit B cells identified for MS

Researchers have identified a subset of B cells that contribute to multiple sclerosis pathology independently of antibody production.

22 Oct 2015

Support for enteric nervous system pathology in prodromal PD

Researchers have found positive immunostaining of α-synuclein in the enteric nervous system of patients with idiopathic rapid eye movement sleep behaviour disorder, suggesting it may have a possible role as a biomarker for prodromal Parkinson’s disease.

22 Oct 2015