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Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

A research team from Spain has prepared a Cochrane systematic review that explores the efficacy, safety, and adherence to fixed-dose combinations (FDCs) of drugs versus single-drug formulations to treat people who are newly diagnosed with tuberculosis (TB).

23 May 2016

Inhibiting palmitate-adding enzyme can make cancer cells sensitive to EGFR inhibitors

The mistaken activation of certain cell-surface receptors contributes to a variety of human cancers. Knowing more about the activation process has led researchers to be able to induce greater vulnerability by cancer cells to an existing first-line treatment for cancers (mainly lung) driven by a receptor called EGFR.

23 May 2016

New microfluidic device helps extract rare target cells from background cells

A team of researchers from University of Cincinnati in Cincinnati, OH have developed a novel microfluidic device, which combines the inertial effect of fluid and microscale vortices generated in microchambers, to achieve simultaneous double sorting of rare target cells and removal of background cells.

23 May 2016

New, easy-to-use method for rapid testing of neutrophil chemotaxis

A team of researchers from the University of Manitoba in collaboration with local clinical scientists in Winnipeg, Canada, have developed a new method for rapid neutrophil chemotaxis test directly from a small drop of whole blood using a microfluidic system.

23 May 2016

Health professionals should make parents aware of SIDS risk factors

New research indicates parents want paediatricians to give them detailed information about their child's death.

23 May 2016

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Doctors worried about dangerous blood clots in patients undergoing a coronary artery procedure— such as angioplasty to treat a heart attack — will often administer antiplatelet therapy to head off complications.

22 May 2016

New method helps scavenge inflammatory molecules that mediate sepsis in mice

Sepsis is a life-threatening complication of infection in which the molecules that the body releases to fight an infection trigger widespread inflammatory responses, resulting in damage to multiple organ systems.

22 May 2016

New collaborative research center to investigate promising aspects of mucosal immunology

Immunology - and the idea that many diseases can best be addressed by boosting the body's own immune response - is one of the hottest areas in medical research and clinical treatment.

22 May 2016

Nanoparticles of ultrapure silicon act as luminescent markers in early diagnosis of cancer

The group of Russian and French researchers, with the participation of scientists from the Lomonosov Moscow State University, has succeeded to synthesize nanoparticles of ultrapure silicon, which exhibited the property of efficient photoluminescence, i.e., secondary light emission after photoexcitation.

22 May 2016

Administering TXA through IV and IA can reduce blood loss following total knee replacement

A new study appearing in the Journal of Bone and Joint Surgery found that administering tranexamic acid (TXA) both intravenously (IV) and injected at the surgical site (intra-articular administration, or IA) reduced blood loss by 37 percent, compared to IV alone, following total knee replacement (TKR).

22 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

Two-way communication between cancer cells may be key to tumor metastasis

Two-way communication between cancer cells appears to be key to their becoming motile, clustering and spreading through metastasis, according to Rice University scientists.

21 May 2016

Research provides pathway toward creation of first broad-spectrum antiviral drug

By studying the rare person -- about one in a million -- who can fight off viral infections more effectively than everyone else, investigators at the Icahn School of Medicine at Mount Sinai have developed a strategy to help the rest of us achieve this enhanced anti-viral state.

21 May 2016

Medical Research News

Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

Inhibiting palmitate-adding enzyme can make cancer cells sensitive to EGFR inhibitors

New microfluidic device helps extract rare target cells from background cells

New, easy-to-use method for rapid testing of neutrophil chemotaxis

Health professionals should make parents aware of SIDS risk factors

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

New method helps scavenge inflammatory molecules that mediate sepsis in mice

New collaborative research center to investigate promising aspects of mucosal immunology

Nanoparticles of ultrapure silicon act as luminescent markers in early diagnosis of cancer

Administering TXA through IV and IA can reduce blood loss following total knee replacement

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

Two-way communication between cancer cells may be key to tumor metastasis

Research provides pathway toward creation of first broad-spectrum antiviral drug

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Regular use of laxatives may flatten rigidity found in Parkinson's disease

GMU’s early-detection urine test works for Lyme disease, study shows

LIGR-Seq tool opens door to developing new understanding of ncRNA function

Umea University researchers find link between vitamin E and brain tumours

New experimental model may predict eventual cardiac phenotype in pediatric patients

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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