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IQWiG examines whether ramucirumab drug offers added benefit for MCRC and NSCLC patients

Ramucirumab is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours.

6 Jun 2016

Study finds no added benefit of empagliflozin alone or in combination for type 2 diabetes

Empagliflozin has been approved since May 2014 for adults with type 2 diabetes mellitus in whom diet and exercise alone do not provide adequate glycaemic control.

6 Jun 2016

Delivering genetic test results over the phone may help ease cost, burden for at-risk cancer patients

Delivering genetic test results to patients at risk for cancer-causing genetic mutations over the phone helps to ease cost and transportation burdens and, compared to receiving results in person, does not cause patients additional stress, according to a new study from the Abramson Cancer Center of the University of Pennsylvania which will be presented at the American Society of Clinical Oncology Annual Meeting.

6 Jun 2016

Study offers more insights into how sensory experiences shape brain development

Most people encounter most things by sensing them in multiple ways. As we hear the words people speak, we also see their lips move. We smell, see and hear the onions as we chop them -- and we feel them with teary eyes.

6 Jun 2016

Cobimetinib combined with vemurafenib shows added benefit for melanoma with BRAF V600 mutation

Cobimetinib has been approved since November 2015 in combination with vemurafenib for the treatment of adults with advanced, i.e. metastatic or unresectable, melanoma with a BRAF V600 mutation.

6 Jun 2016

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

Drugs to treat cancer and Alzheimer's disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting of surface-accessible "pockets" with a specific, well-defined structure.

6 Jun 2016

Rare DNA alteration may increase rsk of multiple sclerosis

Scientists at the University of British Columbia and Vancouver Coastal Health have proven that multiple sclerosis (MS) can be caused by a single genetic mutation - a rare alteration in DNA that makes it very likely a person will develop the more devastating form of the neurological disease.

6 Jun 2016

Intellectually challenging job linked to better memory, cognitive functioning

Working in a more intellectually challenging job is associated with better memory and other aspects of cognitive functioning, reports a study in the June Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine.

6 Jun 2016

Giving chemotherapy after radiotherapy delays rare brain tumour growth

GIVING chemotherapy after radiotherapy delays further growth of a rare type of brain tumour, increasing the number of patients alive at five years from 44 per cent to 56 per cent.

6 Jun 2016

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Researchers at the University of Cincinnati College of Medicine have found that adding increasing doses of an approved Type 2 diabetes drug, metformin, to a chemotherapy and radiation treatment regimen in head and neck cancer patients is not well tolerated if escalated too quickly, but allowing slower escalation could be beneficial.

6 Jun 2016

Study finds link between stress hormone and stage of schizophrenia

JCU Associate Professor Zoltan Sarnyai said it was the first meta-analysis study to compare the level of cortisol in a waking patient's body with the stage of schizophrenia they are suffering.

6 Jun 2016

Early social deprivation may lower DNA methylation within stress-related genes

New research suggests that early severe social deprivation may impact DNA modifications that affect the expression of stress-related genes. These nongenetic (or epigenetic) modifications occur when molecules called methyl groups are added to components of DNA.

6 Jun 2016

Joint research reveals key mechanisms of persistent latent infection of HTLV-1

Joint research between scientists from Kumamoto University, Japan and Imperial College London, UK has revealed the mechanisms of persistent latent infection of the human T-cell leukemia virus type 1 (HTLV-1).

6 Jun 2016

Experts highlight need for change in neuroscience training

Call them the Brain Generation -- the tens of thousands of college and graduate students working toward degrees in neuroscience, and the high school students who want to join them someday.

6 Jun 2016

Study: Majority of food, beverage products endorsed by music celebrities are unhealthy

Recording artists are frequently the face of commercial products—and children and adolescents are frequently their target audience. Now, a new study by researchers at NYU Langone Medical Center finds that the vast majority of the food and beverage products marketed by some of the most popular music stars are unhealthy.

6 Jun 2016

Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Patients with recurrent high-grade glioma brain tumors have few effective treatment options and the majority of available therapies do not improve survival. Moffitt Cancer Center will present preliminary results from a phase 1 study testing whether the addition of pembrolizumab to radiation therapy and bevacizumab is safe and can control tumor growth for these patients.

6 Jun 2016

Autoimmune diseases among lung cancer patients may make them unsuitable for immunotherapy

A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT Southwestern Medical Center's Harold C. Simmons Comprehensive Cancer Center has found.

6 Jun 2016

Gene dysregulation makes immune therapies less effective against metastatic melanoma

Patients who don't respond to treatments that use their own immune cells to destroy tumors, called tumor infiltrating lymphocytes, share changes in mechanisms that switch genes on or off in those cells, according to study results presented at the annual meeting of the American Society for Clinical Oncology on June 4 in Chicago.

6 Jun 2016

Understanding chemotherapy cost differences could help patients in making informed decisions

Costs associated with different breast cancer chemotherapy regimens can vary significantly, regardless of effectiveness, according to new research from The University of Texas MD Anderson Cancer Center. Understanding cost differences should help guide informed discussions between patients and physicians when considering chemotherapy options.

6 Jun 2016

Novel treatment combination helps combat hard-to-treat pediatric neuroblastoma

For seven months, three-year-old Emil Abbasov underwent chemotherapy to fight the tangerine-sized, cancerous tumor growing in his abdomen. But each time, the tumor resisted harder. Each time, he felt more side effects.

6 Jun 2016

Medical Research News

IQWiG examines whether ramucirumab drug offers added benefit for MCRC and NSCLC patients

Study finds no added benefit of empagliflozin alone or in combination for type 2 diabetes

Delivering genetic test results over the phone may help ease cost, burden for at-risk cancer patients

Study offers more insights into how sensory experiences shape brain development

Cobimetinib combined with vemurafenib shows added benefit for melanoma with BRAF V600 mutation

New study finds alternative approaches to target proteins sustaining cancer, Alzheimer's disease

Rare DNA alteration may increase rsk of multiple sclerosis

Intellectually challenging job linked to better memory, cognitive functioning

Giving chemotherapy after radiotherapy delays rare brain tumour growth

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Study finds link between stress hormone and stage of schizophrenia

Early social deprivation may lower DNA methylation within stress-related genes

Joint research reveals key mechanisms of persistent latent infection of HTLV-1

Experts highlight need for change in neuroscience training

Study: Majority of food, beverage products endorsed by music celebrities are unhealthy

Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Autoimmune diseases among lung cancer patients may make them unsuitable for immunotherapy

Gene dysregulation makes immune therapies less effective against metastatic melanoma

Understanding chemotherapy cost differences could help patients in making informed decisions

Novel treatment combination helps combat hard-to-treat pediatric neuroblastoma

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