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Nivolumab and ipilimumab combination could lead to effective treatment options for SCLC patients

Small cell lung cancer (SCLC) represents approximately 14 percent of all types of lung cancer. Many patients with SCLC respond to initial chemotherapy; however, they eventually relapse and develop progressive disease that has no effective treatment options.

2 Jun 2016

Severe obesity may contribute to infection risk after bypass surgery

Severely obese patients who undergo a coronary artery bypass are more likely to develop an infection after surgery and stay in hospital longer, compared with people of normal weight, according to a study published in the Journal of the American Heart Association.

2 Jun 2016

TxCell, LIED collaborate to develop CAR-Treg-based cellular immunotherapy for bullous pemphigoid

TxCell SA, a biotechnology company developing innovative, personalized cellular immunotherapies using regulatory T cells to treat severe chronic inflammatory and autoimmune diseases, today announces the signature of a strategic R&D collaboration agreement with the Lübeck Institute of Experimental Dermatology, a leading institution in the field of translational research on skin blistering diseases, part of the University of Lübeck in Germany.

2 Jun 2016

PAN-EX supports neoadjuvant chemotherapy in high-risk rectal cancer

Patients with high-risk, locally advanced rectal cancer could benefit from neoadjuvant chemotherapy before undergoing chemoradiotherapy, suggest the results of a pooled analysis.

2 Jun 2016

Scientists reveal how ER+ breast cancer uses cholesterol-based molecule to evade anti-hormone treatments

New research funded by Breast Cancer Now has identified how the most common breast cancers could be using a cholesterol-based molecule to evade standard anti-hormone treatments, causing patients’ disease to return.

2 Jun 2016

Researchers explore use of miR-192 as clinical marker for pancreatic cancer

Pancreatic cancer is regarded as the cancer type with the lowest survival rates. Fewer than seven in 100 patients survive the first five years after diagnosis. Clinicians attribute this devastating prognosis to two circumstances: Pancreatic cancers often do not cause any signs or symptoms and by the time they are detected they have already reached a very advanced stage in most cases.

2 Jun 2016

GET.ON online training course can effectively reduce depression risk

Inspired by promising tests of web-based health intervention measures, the researchers aimed to find out whether the risk of developing depression could be reduced by a six-week online training course called GET.ON. GET.ON is based on established therapy methods involving systematic problem solving and behavioural activation.

2 Jun 2016

Supportive leadership can help overcome language barriers to educate new parents about SBS/AHT

Language is a key obstacle to meeting guidelines for educating parents of newborns about "shaken baby syndrome"—also called abusive head trauma (SBS/AHT), reports a study in the Journal of Trauma Nursing, official publication of the Society of Trauma Nurses. The journal is published by Wolters Kluwer.

2 Jun 2016

New mouse model offers more insight into development of ASD in humans

A new mouse model, developed by researchers at the University of Wisconsin-Madison, is the first to show that when more of a specific biological molecule moves between different parts of nerve cells in the mouse brain, it can lead to behaviors that resembles some aspects of autism spectrum disorder (ASD) in humans.

2 Jun 2016

Study finds beer consumption may protect against Aβ aggregation in the brain

While most people will agree that excessive consumption of alcohol can have a detrimental effect on the brain, there is less agreement regarding the effects of light or moderate drinking.

2 Jun 2016

Scientists use optogenetics technique to increase memory in mice brain

Raül Andero Galí, one of the heads of the "Neurobiology of Stress and Addiction" research group at the Institut de Neurociències of the Universitat Autònoma de Barcelona and researcher at Harvard University, published an article in which, for the first time in Spain, optogenetics was used to increase memory.

2 Jun 2016

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Scientists at the University of Liverpool have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure.

2 Jun 2016

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

The average healthy man is 54 percent muscle by mass, but people with muscular dystrophy, an incurable, genetic condition, have almost no muscle at terminal stages of the disease.

2 Jun 2016

New HET wearable system may help track user’s wellness to predict asthma attacks

Researchers have developed an integrated, wearable system that monitors a user's environment, heart rate and other physical attributes with the goal of predicting and preventing asthma attacks.

2 Jun 2016

RSI-MRI imaging technology can effectively differentiate aggressive prostate cancer

Physicians have long used magnetic resonance imaging (MRI) to detect cancer but results of a University of California San Diego School of Medicine study describe the potential use of restriction spectrum imaging (RSI) as an imaging biomarker that enhances the ability of MRI to differentiate aggressive prostate cancer from low-grade or benign tumors and guide treatment and biopsy.

2 Jun 2016

Prenatal mild viral assault may cause central nervous system malfunctions in children

Babies born to mothers whose immune systems had to grapple with a viral assault -- even a mild one -- have increased risk of brain and central nervous system abnormalities, according to a new study.

2 Jun 2016

Infection may trigger development of Alzheimer's disease

A growing body of research on Alzheimer's disease suggests an infectious trigger for the development of the disease. According to Brian Balin, PhD, professor of pathology and chair of bio-medical sciences at Philadelphia College of Osteopathic Medicine, this could be the key to stopping the destructive process of Alzheimer's before it even starts.

2 Jun 2016

Medical Research News

Nivolumab and ipilimumab combination could lead to effective treatment options for SCLC patients

Severe obesity may contribute to infection risk after bypass surgery

TxCell, LIED collaborate to develop CAR-Treg-based cellular immunotherapy for bullous pemphigoid

PAN-EX supports neoadjuvant chemotherapy in high-risk rectal cancer

Scientists reveal how ER+ breast cancer uses cholesterol-based molecule to evade anti-hormone treatments

Researchers explore use of miR-192 as clinical marker for pancreatic cancer

GET.ON online training course can effectively reduce depression risk

Supportive leadership can help overcome language barriers to educate new parents about SBS/AHT

New mouse model offers more insight into development of ASD in humans

Study finds beer consumption may protect against Aβ aggregation in the brain

Scientists use optogenetics technique to increase memory in mice brain

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Study reveals gpihbp1 gene could be novel target for treatment of muscular dystrophy

New HET wearable system may help track user’s wellness to predict asthma attacks

RSI-MRI imaging technology can effectively differentiate aggressive prostate cancer

Prenatal mild viral assault may cause central nervous system malfunctions in children

Infection may trigger development of Alzheimer's disease

Excess phosphates in foods may lead to abnormally high blood pressure

New IRAP inhibitors may hold promise for improving cognitive functions in animal models

Right carbohydrate intake linked to healthy aging

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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