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Genomic cfDNA profiling feasible in metastatic CRPC

Comprehensive genomic profiling of cell-free DNA can provide clinically useful information in men with castration-resistant prostate cancer treated with enzalutamide, research indicates.

14 May 2016

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

Non-steroidal anti-inflammatory drugs (NSAIDs)—including ibuprofen, diclofenac, naproxen and others—are commonly used pain medications that are generally safe but may increase the risk of developing stomach and intestinal ulcers.

13 May 2016

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

With more than 36.9 million people infected globally, HIV continues to be a major public health issue. Those living with the virus are at an increased risk for other non-AIDS diseases, such as cardiovascular disease and cancer, and though it's not entirely clear why, this has been associated with inflammation and abnormal blood clotting.

13 May 2016

Cedars-Sinai researchers explore whether healthy lifestyle choices can slow or prevent Alzheimer's disease

Cedars-Sinai neuroscience researchers are studying whether extensive changes in lifestyle among patients with mild cognitive impairment can slow the progression of Alzheimer's disease.

13 May 2016

International study shows direct link between continued marijuana use during pregnancy and pre-term birth

International research led by the University of Adelaide has for the first time shown a direct link between continued marijuana use during pregnancy and pre-term birth.

13 May 2016

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

Arterial switch to the 12 o'clock position is associated with abnormal coronary perfusion in adolescence, reveals research presented today at EuroCMR 2016.1 Babies born with transposition of the great arteries (TGA) undergo the arterial switch operation in the first days of life.

13 May 2016

New optimised PCR tests for reliable diagnosis of Zika virus

DZIF scientists from the University of Bonn have shown that not all conventional Zika virus molecular diagnostic tests for are sufficiently reliable. They developed optimised assays and a control for quantifying viruses in blood and urine.

13 May 2016

Novel ‘Catch It’ smartphone app can help people manage their problems

In a joint project between the Universities of Liverpool and Manchester researchers have examined the initial trial of a smartphone application designed to help people manage their problems.

13 May 2016

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Myocardial fibrosis could be a future therapeutic target after researchers found it correlated with adverse cardiovascular outcomes in patients with obstructive sleep apnoea (OSA) referred for cardiac magnetic resonance (CMR).

13 May 2016

Study finds no link between weekend staffing levels and patient deaths

The ‘weekend effect’ – that patients admitted to hospital over the weekend are at an increased risk of death – overshadows a much more complex pattern of weekly changes in quality of care, which are unlikely to be addressed by simply increasing the availability of hospital doctors on Saturdays and Sundays, according to two new studies published in The Lancet.

13 May 2016

Genes linked to educational attainment expressed in the brain during prenatal development

An international group of 253 scientists has conducted one of the largest genetic studies to date and identified 74 genetic variants that are associated with the years of formal education that an individual completes.

13 May 2016

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

In a pair of related studies, chemists from the Florida campus of The Scripps Research Institute (TSRI) have identified and designed dozens of molecular “warheads” that not only can detect a key biomarker of cancer, but also could be developed into a potent new class of drug candidates for a range of diseases.

13 May 2016

Researchers identify out of control immune system linked to neurodegenerative diseases

AN out of control immune system has been identified as a possible cause of neurodegenerative diseases such as Alzheimer’s.

13 May 2016

WHO: Air pollution levels increase in low- and middle income cities

More than 80% of people living in urban areas that monitor air pollution are exposed to air quality levels that exceed the World Health Organization limits. While all regions of the world are affected, populations in low-income cities are the most impacted.

13 May 2016

BioNano study describes use of Irys System with Illumina-based NGS methods to achieve high-quality genomic assemblies

BioNano Genomics, the leader in physical genome mapping, today announced publication of another study describing application of its next-generation mapping (NGM) technology as the critical component in achieving high-quality de novo human genome assemblies with unprecedented contiguity.

13 May 2016

New CMR imaging technique increases accuracy by eliminating patients' need to breathe naturally

A new technique for cardiac magnetic resonance (CMR) imaging improves accuracy by removing patients' need to breathe, reveals research presented today at EuroCMR 2016 by Professor Juerg Schwitter, director of the Cardiac MR Centre at the University Hospital Lausanne, Switzerland.

13 May 2016

On-treatment relapse drives disability accrual in MS patients

Frequent relapse activity appears to be a key driver of disability accrual in patients with relapse-onset multiple sclerosis, indicates a study of patients receiving first-line injectable disease-modifying treatment.

13 May 2016

Maternal stress, depression during pregnancy may activate protective mechanisms in infants

Maternal stress and depression during pregnancy may activate certain protective mechanisms in babies. Psychologists from the University of Basel together with international colleagues report that certain epigenetic adaptations in newborns suggest this conclusion.

13 May 2016

Rotavirus vaccine program reduces hospitalization rates by more than 70% in Ontario

Hospitalization for rotavirus infections decreased by > 70% following the introduction of a vaccine program in Ontario, Canada, according to a study published May 11, 2016 in the open-access journal PLOS ONE by Sarah Wilson from Public Health Ontario and the Institute for Clinical Evaluative Sciences, Canada, and colleagues.

13 May 2016

ISSCR releases updated guidelines for stem cell research, development of new therapies

The International Society for Stem Cell Research, the world's largest professional organization of stem cell scientists, today released newly updated guidelines for stem cell research and the development of new clinical therapies.

13 May 2016

Medical Research News

Genomic cfDNA profiling feasible in metastatic CRPC

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

Cedars-Sinai researchers explore whether healthy lifestyle choices can slow or prevent Alzheimer's disease

International study shows direct link between continued marijuana use during pregnancy and pre-term birth

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

New optimised PCR tests for reliable diagnosis of Zika virus

Novel ‘Catch It’ smartphone app can help people manage their problems

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Study finds no link between weekend staffing levels and patient deaths

Genes linked to educational attainment expressed in the brain during prenatal development

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

Researchers identify out of control immune system linked to neurodegenerative diseases

WHO: Air pollution levels increase in low- and middle income cities

BioNano study describes use of Irys System with Illumina-based NGS methods to achieve high-quality genomic assemblies

New CMR imaging technique increases accuracy by eliminating patients' need to breathe naturally

On-treatment relapse drives disability accrual in MS patients

Maternal stress, depression during pregnancy may activate protective mechanisms in infants

Rotavirus vaccine program reduces hospitalization rates by more than 70% in Ontario

ISSCR releases updated guidelines for stem cell research, development of new therapies

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Synthetic Biology and the Pursuit of Living Diagnostics

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