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Experimental cancer drug Nutlin-3 shows promise in cancelling effects of fragile X syndrome

A University of Wisconsin-Madison researcher who studies the most common genetic intellectual disability has used an experimental drug to reverse — in mice — damage from the mutation that causes the syndrome.

28 Apr 2016

Certain genetic markers linked with depression can also predict who may benefit from exercise

Call it personalized medicine for depression -- but the prescription in this case is exercise, which University of Florida Health researchers have found helps people with certain genetic traits.

28 Apr 2016

IPC PAS‘s chemical sensor can rapidly and effectively detect fungal infections

Fungal infections are a serious problem in modern health care. A critical factor in their successful treatment is time: the faster they are detected, the more effectively dangerous infections can be prevented.

28 Apr 2016

Nurse scientist asks health-care systems to set patients up for mortality cliff

Longer lifespans, due to advances in medicine and public health, mean people are living longer with multiple chronic conditions.

28 Apr 2016

Scientists build semantic atlas to show how human brain organizes language

What if a map of the brain could help us decode people's inner thoughts? Scientists at the University of California, Berkeley, have taken a step in that direction by building a "semantic atlas" that shows in vivid colors and multiple dimensions how the human brain organizes language. The atlas identifies brain areas that respond to words that have similar meanings.

28 Apr 2016

Patients with impaired consciousness show uncontrolled communication between resting-state networks

An international research team has investigated interactions in different states of consciousness and has discovered that patients with severely impaired consciousness show a pathological or uncontrolled communication between resting-state networks.

28 Apr 2016

Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

When you think of a neuron, imagine a tree. A healthy brain cell indeed looks like a tree with a full canopy. There's a trunk, which is the cell's nucleus; there's a root system, embodied in a single axon; and there are the branches, called dendrites.

28 Apr 2016

Researchers develop new quantitative assessment of motor control in kids with cerebral palsy

Children with cerebral palsy frequently undergo invasive surgeries -- lengthening tendons, rotating bones, transferring muscles to new locations -- in hopes of improving their physical ability to walk or move.

28 Apr 2016

Scientists show how HIV enters female reproductive tract

Finding the vulnerable points where HIV enters the female reproductive tract is like searching for needles in a haystack. But Northwestern Medicine scientists have solved that challenge by creating a glowing map of the very first cells to be infected with a HIV-like virus.

28 Apr 2016

Little and often gives exercise benefits in Type 2 diabetes

Sedentary, overweight adults with Type 2 diabetes can improve their cardiometabolic profile by engaging in very brief but regular periods of light walking or resistance exercise, research suggests.

28 Apr 2016

HBcrAg may predict HCC development

Research suggests a role for hepatitis B core-related antigen in the prediction of hepatocellular carcinoma development in nucleos(t)ide analogue treatment-naïve patients with chronic hepatitis B virus infection.

27 Apr 2016

WFA+-M2BP levels linked to liver fibrosis, HCC progression in chronic HBV

Japanese researchers have found that serum levels of glycosylated Wisteria floribunda agglutinin-positive Mac-2 binding protein are a useful marker of not only the degree of liver fibrosis, but also progression to hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

27 Apr 2016

Serum marker may flag liver fibrosis in chronic HBV

Serum levels of Wisteria floribunda agglutinin-positive Mac-2-binding protein may reflect the severity of liver fibrosis in patients with chronic hepatitis B virus infection, say researchers.

27 Apr 2016

Bonn researchers identify new technique to measure activity of brown fat cells

Brown fat cells can burn fat to generate heat. University of Bonn researchers have discovered a new method to measure the activity of brown fat cells in humans and mice. The researchers showed that microRNA-92a can be used as an indirect measure for the activity of energy consuming brown fat cells. They showed that a small blood sample was sufficient. Results were published in "Nature Communications," a well-known scientific journal.

27 Apr 2016

Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

The rise of antibiotic resistant bacterial pathogens is an increasingly global threat to public health. In the United States alone antibiotic resistant bacterial pathogens kill thousands every year.

27 Apr 2016

Research highlights global economic burden of norovirus

While norovirus is often linked in the news to outbreaks on cruise ships, the highly contagious stomach bug sickens nearly 700 million around the world every year and results in roughly $4.2 billion in health care costs and $60.3 billion in societal costs annually, new Johns Hopkins Bloomberg School of Public Health research suggests.

27 Apr 2016

Women less likely to stick to cardiac rehabilitation program than men, study finds

Cardiovascular disease is a leading cause of disability globally. Participation in cardiac rehabilitation programs is associated with significantly lower death, but evidence suggests that women are significantly less likely to stick to a cardiac rehabilitation program than men, according to investigators writing in the Canadian Journal of Cardiology.

27 Apr 2016

Study reveals surprising results that may impair future therapeutic approaches in TGF-beta pathway

Researchers at Helmholtz Zentrum München describe how breast cancer cells challenged with a small-molecule inhibitor targeting specific invasive properties switch to an alternative mode-of-action, rendering them even more aggressive. The results may impair future therapeutic approaches in the TGF-beta pathway and are published in the journal 'Oncotarget'.

27 Apr 2016

People's ability to smell declines with age

You not only pick up aromas through your nose, but also through your mouth while you chew your food. Some people simply can smell better than others and those may enjoy an enhanced flavor of foods. Unfortunately, for some, this ability decreases with age, report Tyler Flaherty and Juyun Lim of Oregon State University in the US in Springer's journal Chemosensory Perception.

27 Apr 2016

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

University Hospitals Case Medical Center is the first surgical site for a Phase 2b clinical trial study to further evaluate the safety and efficacy of an investigational cell therapy for the treatment of chronic motor deficit following an ischemic stroke.

27 Apr 2016

Medical Research News

Experimental cancer drug Nutlin-3 shows promise in cancelling effects of fragile X syndrome

Certain genetic markers linked with depression can also predict who may benefit from exercise

IPC PAS‘s chemical sensor can rapidly and effectively detect fungal infections

Nurse scientist asks health-care systems to set patients up for mortality cliff

Scientists build semantic atlas to show how human brain organizes language

Patients with impaired consciousness show uncontrolled communication between resting-state networks

Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

Researchers develop new quantitative assessment of motor control in kids with cerebral palsy

Scientists show how HIV enters female reproductive tract

Little and often gives exercise benefits in Type 2 diabetes

HBcrAg may predict HCC development

WFA+-M2BP levels linked to liver fibrosis, HCC progression in chronic HBV

Serum marker may flag liver fibrosis in chronic HBV

Bonn researchers identify new technique to measure activity of brown fat cells

Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

Research highlights global economic burden of norovirus

Women less likely to stick to cardiac rehabilitation program than men, study finds

Study reveals surprising results that may impair future therapeutic approaches in TGF-beta pathway

People's ability to smell declines with age

Clinical study to evaluate safety of investigational cell therapy to treat chronic motor deficits after stroke

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