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First European approval of drug to treat genetic kidney disease ADPKD

Otsuka Pharmaceutical Co., Ltd. announced that the European Commission has granted marketing authorisation for JINARC® (tolvaptan) for the treatment of ADPKD in adults who have chronic kidney disease (CKD) stage one to three at initiation of treatment with evidence of rapidly progressing disease

29 May 2015

MIT, UCSD researchers use probiotics to detect cancer in the liver

Engineers at MIT and the University of California at San Diego have devised a new way to detect cancer that has spread to the liver, by enlisting help from probiotics — beneficial bacteria similar to those found in yogurt.

29 May 2015

New EU Clinical Trials Regulation may prove to be challenging for cancer research in Europe

The European Society for Medical Oncology, in collaboration with the European Organisation for Research and Treatment of Cancer, expressed their views on the EU Clinical Trials Regulation in an official position paper recently published in Annals of Oncology.

29 May 2015

New research shows wide variation in organ donation rates across the country

More than 123,000 Americans are currently waiting for lifesaving organ transplants, but 21 patients die each day because there aren't enough organs to go around. New research shows wide variation in the number of eligible organ donors whose loved ones consent to organ donation across the country.

29 May 2015

RI-MUHC researchers receive $1.5 million to develop glutamate biosensor platform for brain diseases

In the human brain and retina, glutamate is an important messenger that carries information from one neuron to another. The level of glutamate transmitted between neurons is crucial to cell communication: too high and neurons die, too low and the information is not communicated properly. In either case this can contribute to neurological diseases including stroke, glaucoma, and Alzheimer's.

29 May 2015

Breakthrough in machine learning could revolutionize medical screening methods

A breakthrough in machine learning has also brought about a "game changer" for the science of metabolomics - and will hasten the development of diagnostic and predictive tests for Alzheimer's, cancer, diabetes and numerous other conditions, leading to improved prevention and treatment.

29 May 2015

Study expands understanding of the production of ET-743 compound

For decades, scientists have known that ET-743, a compound extracted from a marine invertebrate called a mangrove tunicate, can kill cancer cells. The drug has been approved for use in patients in Europe and is in clinical trials in the U.S.

29 May 2015

Scientists reveal why lone kidney gets bigger when the other one is lost

Scientists have found an explanation for the century-old observation that if you end up with just one kidney, the lone organ gets bigger.

29 May 2015

Differences in brain expression of RORA protein levels may lead to sex bias in autism

George Washington University researcher Valerie Hu, Ph.D., has found an important sex-dependent difference in the level of RORA protein in brain tissues of males and females. Specifically, females without autism have a slightly higher level of RORA in the frontal cortex of the brain than males without autism, while the levels of the protein are comparably lower in the brain of both males and females with autism.

29 May 2015

Hodgkin's lymphoma treatment can cause late sequelae

Hodgkin's lymphoma--cancer of the lymph nodes--arises in more than 150 children and adolescents in Germany each year. Nine out of ten patients survive the disease, thanks to the highly effective treatments that are now available. Depending on the type of treatment given, however, there may be late sequelae, as discussed by Wolfgang Dörffel and colleagues in an original article in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2015; 112: 320-7).

29 May 2015

Study explores efficacy of selective serotonin reuptake inhibitors in reducing depressed mood

Many have recently questioned the efficacy of the most common antidepressant medications, the selective serotonin reuptake inhibitors (SSRIs). The conclusion that these drugs are ineffective is however partly based on a misinterpretation of the outcome of the clinical trials once conducted to demonstrate their efficacy. This was the finding of a study conducted by researchers at the Sahlgrenska Academy.

29 May 2015

SDSU researchers awarded NIH grant to understand how autism plays out across the lifespan

In the public consciousness, autism spectrum disorder only affects children. In truth, ASD is a lifelong condition. But how it affects older adults is a gaping unknown in autism research. Now, a new and significant grant from the National Institutes of Health will help researchers at San Diego State University understand how the disorder plays out across the lifespan.

29 May 2015

Study highlights recent trends in non-fatal suicidal events in the U.S. Army

Although the U.S. Army suicide rate is known to have risen sharply over the past decade, information about medically documented, non-fatal suicidal behaviors is far more limited. According to findings published in Psychiatry: Interpersonal & Biological Processes incidence rates of suicide ideation and suicide attempts increased annually among Soldiers during the years 2004-2009.

29 May 2015

DNA analysis reveals how ovarian cancer takes genetic twists and turns to outsmart chemotherapy

The largest complete DNA analysis of ovarian cancer in the world, published overnight in Nature, has revealed unprecedented new insight into the genetic twists and turns a deadly form of the disease takes to outsmart chemotherapy, potentially changing treatment approaches for women around the world.

29 May 2015

Study points to the importance of addressing health-related needs of ex-prisoners

Ex-prisoners with a history of risky drug use, mental illness or poverty are more likely to end up back behind bars. Those who are obese, are chronically ill or have attempted suicide are more likely to remain in the community. These are some of the findings from an exploratory study into health-related factors that could be used to predict whether a person released from prison will end up in custody again.

29 May 2015

Incidence of melanoma on the rise among children and young adults

The incidence of melanoma, a deadly form of skin cancer, has increased by more than 250% among children, adolescents and young adults since 1973, according to award-winning research to be presented by Roswell Park Cancer Institute (RPCI) at the American Society of Clinical Oncology (ASCO) 51st Annual Meeting in Chicago.

29 May 2015

Poor sleep significantly decreases cognitive performance in autistic and neurotypical children

One night of poor sleep significantly decreases performance on intelligence tests in children with autism spectrum disorder (ASD) and also in neurotypical children (without ASD). This is the conclusion made by researchers at the Hôpital Rivière-des-Prairies, affiliated with the Institut universitaire en santé mentale de Montréal and Université de Montréal.

29 May 2015

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Duke Medicine researchers have found that bladder cells have a highly effective way to combat E. coli bacteria that cause urinary tract infections (UTIs).

29 May 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Researchers have uncovered a new molecular mechanism whereby human cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis, which, when it malfunctions, leads to harmful results.

29 May 2015

Strategy-based cognitive training improves cognitive, psychological health after traumatic brain injury

In the first study of its kind, veterans and civilians with traumatic brain injury showed improved cognitive performance and psychological and neural health following strategy-based cognitive training. The Department of Defense-funded study, published this week in Neuropsychological Rehabilitation, was conducted by an interdisciplinary team of cognitive neuroscientists, rehabilitation specialists, and neuroimaging experts from the Center for BrainHealth at The University of Texas at Dallas.

29 May 2015

Medical Research News

First European approval of drug to treat genetic kidney disease ADPKD

MIT, UCSD researchers use probiotics to detect cancer in the liver

New EU Clinical Trials Regulation may prove to be challenging for cancer research in Europe

New research shows wide variation in organ donation rates across the country

RI-MUHC researchers receive $1.5 million to develop glutamate biosensor platform for brain diseases

Breakthrough in machine learning could revolutionize medical screening methods

Study expands understanding of the production of ET-743 compound

Scientists reveal why lone kidney gets bigger when the other one is lost

Differences in brain expression of RORA protein levels may lead to sex bias in autism

Hodgkin's lymphoma treatment can cause late sequelae

Study explores efficacy of selective serotonin reuptake inhibitors in reducing depressed mood

SDSU researchers awarded NIH grant to understand how autism plays out across the lifespan

Study highlights recent trends in non-fatal suicidal events in the U.S. Army

DNA analysis reveals how ovarian cancer takes genetic twists and turns to outsmart chemotherapy

Study points to the importance of addressing health-related needs of ex-prisoners

Incidence of melanoma on the rise among children and young adults

Poor sleep significantly decreases cognitive performance in autistic and neurotypical children

Duke researchers reveal how bladder cells can eject UTI-causing bacteria

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Strategy-based cognitive training improves cognitive, psychological health after traumatic brain injury

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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