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XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

Scientists from Weill Cornell Medical College and Houston Methodist have found that a gene previously unassociated with breast cancer plays a pivotal role in the growth and progression of the triple negative form of the disease, a particularly deadly strain that often has few treatment options. Their research, published in this week's Nature, suggests that targeting the gene may be a new approach to treating the disease.

25 Mar 2014

New subcellular mechanism identified for fast transmission in basket cells of the brain

In his third major research paper since December 2013, IST Austria Professor Peter Jonas together with his collaborator, postdoc Hua Hu, identifies a new subcellular mechanism for reliable, fast transmission in the so-called basket cells of the brain.

25 Mar 2014

Researchers develop one-step analysis for detecting tumor markers in blood

Benign growth, or cancer? Tumor markers in the blood help determine whether the patient is afflicted with a malign tumor and whether it is excreting markers more vigorously - involving highly specific proteins. An increased concentration in the blood provides one indication of the disease for physicians. However, it has been quite expensive in time and effort to detect the markers thus far. This is because all kinds of molecules and proteins are teeming in the blood. To be able to detect a single specific one, doctors must first separate and purify the blood in several steps, and then isolate the marker they are searching for from the rest of the molecules.

25 Mar 2014

Study suggests that self-administration of influenza vaccine may be feasible with microneedle patch

There are many reasons some people may not get a flu shot, but would they be more likely to do so if there was a simple device that could be mailed directly to them, was easy enough to use by themselves, and provided at least the same level of protection as a traditional flu shot without the pain of a needle jab? A recent NIBIB-funded study, published online February 2014 in the journal Vaccine, suggests the answer is yes.

25 Mar 2014

$Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture$

Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture

Studies have shown that anyone age 50 or older who suffers a fragility fracture - a bone break sustained in a fall from a standing height or less - is two to five times more likely to experience a second fracture than someone who hasn't had one. The odds that a person who's suffered two such fractures will have a third are even higher.

25 Mar 2014

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

NeuroVive Pharmaceutical AB (publ) and A1M Pharma AB (publ) have announced that the two companies are initiating a research collaboration in mitochondrial medicine. The partnership is governed by a collaboration agreement signed on 21 March 2014.

25 Mar 2014

New technology gives tool to examine membrane proteins in natural environment of human cell

Scientists have a better way to study human proteins - large molecules that are part of every cell in the body - thanks to a new technology developed by University of Toronto researchers.

25 Mar 2014

Low dose injections of artificial properdin provide protection against septic diseases

Researchers at the University of Leicester have produced an artificial version of a naturally occurring protein, properdin, which has been found to successfully combat bacterial pneumonia and meningitis when tested in mice.

25 Mar 2014

Scientists develop new method to deliver cancer-fighting drugs directly to milk ducts

One of every eight women in the United States will develop breast cancer. Though the incidence of breast cancer began decreasing in 2000, it is still the second-leading cause of cancer death in women.

25 Mar 2014

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

A University of Cincinnati (UC) trauma and critical care researcher has received a National Institutes of Health grant to better understand how "microparticles" in stored blood can contribute to inflammation and injury after resuscitation from traumatic injury.

25 Mar 2014

Smokers find difficult to savor bitter taste of caffeine, says study

Smokers and those who have quit cannot fully appreciate the full flavor of a cup of coffee, because many cannot taste the bitterness of their regular caffeine kick. This is the finding of a study led by Nelly Jacob of the Piti--Salp-tri-re Hospital APHP in France, published in Springer's journal Chemosensory Perception.

25 Mar 2014

Study: Menstrual abnormalities in women with PCOS is strongest predictor for mental health issues

Polycystic ovary syndrome (PCOS), a hormone imbalance that causes infertility, obesity, and excessive facial hair in women, can also lead to severe mental health issues including anxiety, depression, and eating disorders.

25 Mar 2014

New research reveals new complexity to nerve cells in brain that could affect future therapies

Research from the Oklahoma Medical Research Foundation reveals a new complexity to nerve cells in the brain that could affect future therapies aimed at altering mood and memory in humans.

25 Mar 2014

Study uncovers one way that p53 acts to prevent cancer cell invasion

The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive.

25 Mar 2014

Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

Marina Cavazzana, MD, PhD, Paris Descartes University, France and Adrian J. Thrasher, MD, PhD, University College London Institute of Child Health, UK, have been honored with the Pioneer Award for basic and clinical gene therapy for immunodeficiency disorders.

25 Mar 2014

Not all doctors offer cancer gene testing to patients, study finds

Many cancer researchers believe that cutting-edge advances in genomics will pave the way for personalized or "precision" cancer medicine for all patients in the near future. A new study by researchers at Dana-Farber Cancer Institute, however, suggest that not all doctors are ready to embrace tests that look for hundreds of DNA changes in patients' tumor samples, while others plan to offer this type of cancer gene testing to most of their patients.

25 Mar 2014

Scientist receives $275,000 grant to study human papillomavirus that causes head and neck cancer

Basic scientists focus on understanding how things work, so most don't get the chance to directly impact other people's lives. That's why Michelle Ozbun, PhD, is very excited about her recent grant to study human papillomavirus.

25 Mar 2014

Study suggest that women are resistant to mutations that contribute to autism

It takes more mutations to trigger autism in women than in men, which may explain why men are four times more likely to have the disorder, according to a study published 26 February in the American Journal of Human Genetics1.

25 Mar 2014

Researchers use retro approach to produce new drugs

This alternative approach to creating artificial organic molecules, called bioretrosynthesis, was first proposed four years ago by Brian Bachmann, associate professor of chemistry at Vanderbilt University. Now Bachmann and a team of collaborators report that they have succeeded in using the method to produce the HIV drug didanosine.

25 Mar 2014

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease (AD) in the brain and improves learning and memory in two experimental AD models.

25 Mar 2014

Medical Research News

XBP1 gene plays pivotal role in the growth and progression of triple negative breast cancer

New subcellular mechanism identified for fast transmission in basket cells of the brain

Researchers develop one-step analysis for detecting tumor markers in blood

Study suggests that self-administration of influenza vaccine may be feasible with microneedle patch

Fracture liaison services effective in identifying, treating older adults who suffer fragility fracture

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

New technology gives tool to examine membrane proteins in natural environment of human cell

Low dose injections of artificial properdin provide protection against septic diseases

Scientists develop new method to deliver cancer-fighting drugs directly to milk ducts

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

Smokers find difficult to savor bitter taste of caffeine, says study

Study: Menstrual abnormalities in women with PCOS is strongest predictor for mental health issues

New research reveals new complexity to nerve cells in brain that could affect future therapies

Study uncovers one way that p53 acts to prevent cancer cell invasion

Marina Cavazzana, Adrian J. Thrasher honored with Pioneer Award for gene therapy

Not all doctors offer cancer gene testing to patients, study finds

Scientist receives $275,000 grant to study human papillomavirus that causes head and neck cancer

Study suggest that women are resistant to mutations that contribute to autism

Researchers use retro approach to produce new drugs

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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