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Study reveals early nicotinamide use reduces risk of aggressive skin cancers

A large U.S. Department of Veterans Affairs cohort study found that Nicotinamide use was associated with a 14% lower risk of new keratinocyte skin cancers, driven by a 22% reduction in cSCC and no reduction in BCC. The strongest benefit (56% lower risk) appeared when nicotinamide was started after a patient’s first skin cancer, with diminishing returns after multiple cancers.

18 Sep 2025

Climate change is already driving heat mortality and massive economic losses

Researchers systematically identified just 20 studies directly linking human-driven climate change to specific health impacts and deaths worldwide. They estimate tens of billions in annual economic losses and warn of inequities in research leadership and data coverage.

18 Sep 2025

AI model maps lifetime disease risks to transform future healthcare planning

Researchers developed Delphi-2M, a transformer-based AI trained on UK Biobank and Danish health data to predict and simulate lifetime trajectories for 1,256 diseases. It accurately forecasted long-term multimorbidity risks, generated synthetic health records, and highlighted comorbidity patterns while exposing key biases.

18 Sep 2025

PANoptosis emerges as a promising strategy against liver cancer

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

18 Sep 2025

Microplastics pose potential risks to bone health

The production and use of over 400 million tons of plastic each year has polluted beaches, rivers, and even the deepest parts of the ocean, reaching depths of up to 11,000 meters.

18 Sep 2025

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

In a phase 3 trial, once-daily oral orforglipron induced significant, dose-dependent weight loss over 72 weeks in adults with obesity but no diabetes. It also improved multiple cardiometabolic markers with a safety profile similar to other GLP-1 receptor agonists.

18 Sep 2025

Digital twin of lung cancer cell offers new insights into tumor growth and treatment

An enhanced computer model is now helping to provide fresh insights into cancer-cell growth and how it can be stopped. The digital cell model represents another step towards individualized cancer treatment.

18 Sep 2025

Evening meals hold the key to morning glucose control in prediabetes

The way glucose is regulated at night plays a key role in fasting glucose levels the next morning, when blood sugar is expected to be at its lowest.

18 Sep 2025

New class of antibiotics shows potent activity against multidrug-resistant bacteria

Scientists at the University of Liverpool, working with international collaborators, have discovered Novltex, a groundbreaking new class of antibiotics with potent activity against some of the world's most dangerous multidrug-resistant (MDR) bacteria.

18 Sep 2025

Real-time blood testing shows promise for preventing maternal deaths from hemorrhage

Postpartum hemorrhage, severe bleeding after childbirth, is a leading cause of maternal mortality around the world.

18 Sep 2025

Nursing researchers explore new ways to improve the quality of methadone treatment

Researchers at the University of Arizona College of Nursing are testing an intervention to reduce staff stress and improve methadone patient treatment retention for opioid use disorder thanks to a $4.5 million grant from the National Institute on Drug Abuse, a division of the National Institutes of Health.

18 Sep 2025

Timely opioid treatment lowers hospitalizations in children with sickle cell disease

A new study has found that prompt administration of opioid pain relief in emergency departments reduces the likelihood of hospitalization for children with sickle cell disease, according to findings published in JAMA Pediatrics.

18 Sep 2025

HIV protein Tat found to increase vulnerability to tuberculosis

According to the World Health Organization, tuberculosis accounts for one in three deaths among people living with HIV.

18 Sep 2025

Genetic study reveals how Anopheles funestus adapts to malaria control

New research into the genetics of Anopheles funestus (An. funestus), one of the most neglected but prolific malaria-transmitting mosquitoes in Africa, has revealed how this species is evolving in response to malaria control efforts.

18 Sep 2025

Mobile app improves reporting of suspected adverse drug reactions in Uganda

Results from a ground-breaking new trial published in The Lancet Global Health show that a mobile application, Med Safety, improved the reporting of suspected adverse drug reactions (ADRs) by healthcare workers in Uganda.

18 Sep 2025

Muscle hormone FGF21 linked to longer survival in ALS

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled "The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity."

18 Sep 2025

POT1 gene mutation linked to pulmonary fibrosis through telomere dysfunction

Idiopathic pulmonary fibrosis is a potentially fatal disease currently without treatment, in which lung tissue develops scarring and becomes stiff, making breathing increasingly difficult over time.

18 Sep 2025

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain cells communicate, revealing fresh insight into the progression of Alzheimer's disease.

18 Sep 2025

Massage Therapy Foundation funds CHOP study on pediatric irritable bowel syndrome

The Massage Therapy Foundation (MTF) announces the award of a research grant to Children's Hospital of Philadelphia (CHOP). The grant will support a three-year study entitled Myofascial Release Therapy in Irritable Bowel Syndrome led by Primary Investigators Maria Mascarenhas, MBBS and Alain J. Benitez, MD, MSTR.

18 Sep 2025

Cholesterol control improves but cardiovascular disease still increases in Mexico

Despite improved statin use and cholesterol control, cardiovascular disease risk rose in Mexico between 2016 and 2023, according to a study being presented at ACC Latin America 2025 that used region-specific tools to more accurately predict the local disease burden.

18 Sep 2025

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Medical Research News

Study reveals early nicotinamide use reduces risk of aggressive skin cancers

Climate change is already driving heat mortality and massive economic losses

AI model maps lifetime disease risks to transform future healthcare planning

PANoptosis emerges as a promising strategy against liver cancer

Microplastics pose potential risks to bone health

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

Digital twin of lung cancer cell offers new insights into tumor growth and treatment

Evening meals hold the key to morning glucose control in prediabetes

New class of antibiotics shows potent activity against multidrug-resistant bacteria

Real-time blood testing shows promise for preventing maternal deaths from hemorrhage

Nursing researchers explore new ways to improve the quality of methadone treatment

Timely opioid treatment lowers hospitalizations in children with sickle cell disease

HIV protein Tat found to increase vulnerability to tuberculosis

Genetic study reveals how Anopheles funestus adapts to malaria control

Mobile app improves reporting of suspected adverse drug reactions in Uganda

Muscle hormone FGF21 linked to longer survival in ALS

POT1 gene mutation linked to pulmonary fibrosis through telomere dysfunction

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Massage Therapy Foundation funds CHOP study on pediatric irritable bowel syndrome

Cholesterol control improves but cardiovascular disease still increases in Mexico

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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