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Blocking nutrient scavenging weakens pancreatic tumor defenses

Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue, blood vessels and a sea of proteins and carbohydrates that provide structure and other supportive functions.

24 Jul 2025

Salk researcher awarded funding to boost immunotherapy for pancreatic cancer

Salk Institute Professor Diana Hargreaves was named a 2025 All-Star Translational Award Program grantee by the V Foundation for Cancer Research.

24 Jul 2025

Older adults with serious illness face greater burdens after elective surgery

Older adults who have serious illness before undergoing elective surgery had hospital stays twice as long as similarly aged counterparts; were twice as likely to return to the hospital or the emergency department; and had almost double the yearly costs of health care, according to a study published in the Journal of the American College of Surgeons.

24 Jul 2025

IRF-5 identified as key to preventing immune cell exhaustion

In fighting chronic infections or certain cancers, CD8+ T cells-the immune system's frontline soldiers-eventually become exhausted. They lose effectiveness and respond less efficiently to threats.

24 Jul 2025

Expanding mastectomy access could prevent more breast cancer cases

More women at higher risk of breast cancer should be offered a mastectomy, according to a new study led by researchers at the London School of Hygiene & Tropical Medicine (LSHTM) and Queen Mary, University of London.

24 Jul 2025

Standard DNA tests miss most cases of NUT carcinoma

The diagnosis of a suspected lung, head, and neck cancer called NUT carcinoma should include additional testing capable of detecting gene fusions that are definitive markers of the disease, according to a study by Dana-Farber Cancer Institute investigators.

24 Jul 2025

Bias found in AI models diagnosing skin diseases across demographics

An international research team led by Assistant Professor Zhiyu Wan from ShanghaiTech University has recently published groundbreaking findings in the journal Health Data Science, highlighting biases in multimodal large language models (LLMs) such as ChatGPT-4 and LLaVA in diagnosing skin diseases from medical images.

24 Jul 2025

Billing codes in big data often misidentify diagnoses

Use of billing codes in big data sets to find diagnoses can result in up to two-thirds of cases being mistakenly identified, new UCLA-led research finds.

24 Jul 2025

Automated cage monitoring system reveals behavioral changes in schizophrenia mouse model

Schizophrenia is a serious mental health condition that affects thoughts, moods, perceptions, and behaviors.

24 Jul 2025

Exploring tick microbiota and their impact on disease transmission

Announcing a new article publication for Zoonoses journal. Ticks have garnered significant research interest owing to their ability to vector pathogens into humans and animals.

24 Jul 2025

Different anti-PD-L1 antibodies show varied results in tumor growth inhibition

Immune checkpoint inhibitors (ICIs), a powerful form of immunotherapy, have revolutionized cancer treatment by unleashing the body's own immune system to fight tumors.

24 Jul 2025

New study reveals high lifetime exposure to hepatitis B and C in Ukraine

A study just published on Eurosurveillance has found evidence of substantial lifetime exposure to hepatitis B and C viruses in Ukraine in a 2021 nationwide, representative sample of the population, with findings also suggesting significant ongoing circulation of these viruses.

24 Jul 2025

New redox-sensitive pathway reveals how cells activate AMPK in response to metabolic stress

AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.

24 Jul 2025

Ibogaine treatment shows major breakthrough for veterans with brain injuries

Now, Stanford Medicine researchers have discovered that the plant-based psychoactive drug ibogaine, when combined with magnesium to protect the heart, safely and effectively reduces PTSD, anxiety and depression and improves functioning in veterans with TBI.

24 Jul 2025

Ketamine's antidepressant effects involve the brain's opioid system

Ketamine is a highly effective, fast-acting antidepressant that works even for patients who have not responded to other medications.

24 Jul 2025

Promising therapeutic approach identified for multiple myeloma

Researchers at Uppsala University have identified a promising therapeutic approach for the challenging blood cancer multiple myeloma.

24 Jul 2025

Study finds continued use of risky antiseizure drugs during pregnancy

Despite evidence of the risk of malformations at birth, or birth defects, use of some antiseizure drugs during pregnancy has persisted, according to a study published on July 23, 2025, in Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2025

Penn State team investigates the neural basis of nightmares and mental health

Dreams, and likely nightmares, are experienced universally across humans and animals, but neuroscientists still do not know why.

24 Jul 2025

Walking 7,000 steps per day associated with reductions in risk of several serious health problems

A comprehensive new study analyzing data from over 160,000 adults finds that walking approximately 7,000 steps per day is associated with reductions in the risk of several serious health outcomes, including all-cause mortality (47% reduction), cardiovascular disease (25% reduction), cancer (6% reduction), type 2 diabetes (14% reduction), dementia (38% reduction), depression (22% reduction), and falls (28% reduction).

24 Jul 2025

Open-source AI tool matches commercial systems in medical scan reporting

A new study from the University of Colorado Anschutz Medical Campus shows that free, open-source artificial intelligence (AI) tools can help doctors report medical scans just as well as more expensive commercial systems without putting patient privacy at risk.

24 Jul 2025