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Dental floss may offer a novel vaccine delivery method

Researchers have demonstrated a novel vaccine delivery method in an animal model, using dental floss to introduce vaccine via the tissue between the teeth and gums.

28 Jul 2025

Understanding immune drift in biologic therapy for inflammatory skin diseases

Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4).

28 Jul 2025

Restoring mitochondria enhances immune response against lung cancer

While chemotherapy remains a cornerstone of lung cancer treatment, it often weakens the immune system it relies on for long-term control.

28 Jul 2025

TraMA offers breakthrough in measuring biological age

A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled "Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA)."

28 Jul 2025

Metabolic rewiring turns immune cells into potent cancer fighters

Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer.

28 Jul 2025

Vitamin D supplementation reduces liver inflammation and fibrosis largely through TXNIP

Chronic liver disease (CLD) is a major global health concern, affecting approximately 1.5 billion people. This life-threatening disease often progresses silently, eventually leading to worsened conditions like liver cirrhosis or liver cancer.

28 Jul 2025

Marbling of fat inside muscles found to block healing and weaken strength

Consider the delicate web of fat in a Wagyu steak. The "marbling" that makes carnivore connoisseurs swoon is a visual heuristic for quality flavor.

28 Jul 2025

Neutrophils emerge as key players in cancer progression and therapy

Neutrophils are the most abundant type of white blood cells, critical for immune defense and inflammation control.

28 Jul 2025

Study: Formal education does not slow brain aging or cognitive decline

An international study published in the journal Nature Medicine casts doubt on the widespread belief that higher levels of formal education directly protect against cognitive decline and brain aging.

28 Jul 2025

Columbia engineers create bioactive hydrogels using dairy-derived EVs

Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.

28 Jul 2025

Largest genetic study confirms biological basis of stuttering

The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk.

28 Jul 2025

Study reveals a strong link between early childhood adversities and depression in older Canadians

A new study of 3,500 Canadians aged 55 and older revealed a strong association between early childhood adversities and depression.

28 Jul 2025

Study shows the importance of diet in influencing multimorbidity in aging populations

A healthy diet can slow down the accumulation of chronic diseases in older adults, while inflammatory diets accelerate it.

28 Jul 2025

Australian scientists uncover new way to halt aggressive cancer growth

Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by targeting a specialized molecular process known as 'minor splicing'.

28 Jul 2025

Promising new male birth control pill could be taken every three days

YCT-529, a novel non-hormonal male contraceptive, demonstrates safety and tolerability in early trials, offering a potential solution for male birth control.

28 Jul 2025

Persistent intense grief linked to higher healthcare use and mortality

Grief after the loss of a loved one is a natural response – an inevitable part of living and loving. But in a minority of the bereaved, grief is so overwhelming that it can lead to physical and mental illnes, even if they don't necessarily qualify for a diagnosis with the mental health condition 'prolonged grief disorder'.

28 Jul 2025

Addressing diagnostic delays in dementia for better patient outcomes

People with dementia are diagnosed an average of 3.5 years after symptoms are first noticed, or even longer (4.1 years) for those with early-onset dementia, finds a new study led by UCL researchers.

28 Jul 2025

Researchers map atomic structure of protein complex driving cilia movement

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

28 Jul 2025

UCSF discovery points to new strategies for Alzheimer's treatment

UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, with devastating consequences for the brain.

28 Jul 2025

Predicting measles vaccination coverage for targeted public health action

Knowing how many people are vaccinated against an existing or re-emerging threat is a key factor guiding public health decisions, but such information is often sparse or non-existent in many regions, according to researchers at Penn State.

28 Jul 2025