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Breakthrough research identifies pathway used by glioblastoma to infiltrate the brain

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University.

2 Aug 2024

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for treating acute lymphoblastic leukemia (ALL).

2 Aug 2024

Study reveals how coinfecting phages impede each other’s entry into bacterial cells

The process by which phages - viruses that infect and replicate within bacteria - enter cells has been studied for over 50 years.

2 Aug 2024

New research reveals keto diet’s impact on cholesterol and gut microbiome

A study from the University of Bath reveals that ketogenic low-carbohydrate diets can increase cholesterol levels and reduce beneficial gut bacteria, specifically Bifidobacterium.

2 Aug 2024

Study links e-cigarette use to increased respiratory symptoms

The association between electronic cigarette (EC) use and respiratory health in adults.

2 Aug 2024

Impact of early COVID-19 job loss on later mental health uncovered

How income or job loss during the initial phases of the coronavirus disease 2019 (COVID-19) pandemic is linked to subsequent psychological distress.

2 Aug 2024

New frontiers in organ regeneration with 3D bioprinting

In a latest review published in Engineering, an international team of scientists from China and the United States has presented a comprehensive analysis of the latest advancements in 3D organ bioprinting. This innovative technology holds the potential to revolutionize regenerative medicine and tackle some of the most pressing issues in organ transplantation.

2 Aug 2024

Uncovering hidden drug benefits through protein mapping

Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. For the first time, researchers at the Technical University of Munich (TUM) have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help to identify previously unknown potential benefits of existing drugs.

2 Aug 2024

Study reveals new H5N1 variants evade human antibodies more effectively

In a new study led by UNC Charlotte researchers from the Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) and the North Carolina Research Campus at Kannapolis, University scholars have found evidence that the latest variants of H5N1 influenza - commonly known as avian or bird flu - are better at evading antibodies, including those of humans, than previous iterations of the virus.

2 Aug 2024

Researchers identify strategy to design safer opioids

Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose.

2 Aug 2024

Severe PTSD characterized by lower oxytocin and higher vasopressin levels

Research finds PTSD marked by reduced oxytocin and elevated vasopressin, suggesting AVP/OT ratios as potential biomarkers for diagnosis and treatment response.

1 Aug 2024

Trust in US physicians and hospitals plummeted during COVID-19, impacting vaccination rates

Trust in US physicians and hospitals dropped significantly during COVID-19, affecting vaccination rates across all demographics. Restoring trust is crucial for future public health efforts.

1 Aug 2024

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity.

1 Aug 2024

Groundbreaking method dmSLAY improves antimicrobial peptide effectiveness and safety

Researchers developed a high-throughput method, dmSLAY, to assess thousands of AMP variants, combining it with machine learning to enhance membrane selectivity and reduce toxicity.

1 Aug 2024

Oropouche virus: Emerging threats and unanswered questions

Announcing a new article publication for Zoonoses journal. Oropouche virus (genus Orthobunyavirus, family Peribunyaviridae) is an arthropod-borne virus that infects several species of animals and humans, primarily in South America.

1 Aug 2024

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Researchers discovered diverse and stable immune cell populations in the upper respiratory tract, highlighting the critical role of mucosal immunity in COVID-19 and other respiratory diseases.

1 Aug 2024

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR).

1 Aug 2024

Comprehensive meta-analysis offers insights into strategies for increasing immunization uptake

Vaccines are safe and effective, and help reduce death and illness. But global vaccination rates are suboptimal and have trended downward, leaving humanity more vulnerable to vaccine-preventable diseases such as COVID-19, influenza, measles, polio, and HPV.

1 Aug 2024

Telemedicine usage can have unexpected impact on rural communities' access to local care

Remote healthcare delivery, commonly known as telehealth or telemedicine, is often beneficial for patients who have difficulty visiting their preferred healthcare providers in person.

1 Aug 2024

Age and cultural pressures shape body appreciation among women worldwide

A study in PLOS ONE reveals that body appreciation is significantly influenced by ethnicity and sociocultural pressures, with Black Nigerian women reporting the highest satisfaction and White Western women the lowest.

1 Aug 2024

Medical Research News

Breakthrough research identifies pathway used by glioblastoma to infiltrate the brain

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

Study reveals how coinfecting phages impede each other’s entry into bacterial cells

New research reveals keto diet’s impact on cholesterol and gut microbiome

Study links e-cigarette use to increased respiratory symptoms

Impact of early COVID-19 job loss on later mental health uncovered

New frontiers in organ regeneration with 3D bioprinting

Uncovering hidden drug benefits through protein mapping

Study reveals new H5N1 variants evade human antibodies more effectively

Researchers identify strategy to design safer opioids

Severe PTSD characterized by lower oxytocin and higher vasopressin levels

Trust in US physicians and hospitals plummeted during COVID-19, impacting vaccination rates

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

Groundbreaking method dmSLAY improves antimicrobial peptide effectiveness and safety

Oropouche virus: Emerging threats and unanswered questions

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

Comprehensive meta-analysis offers insights into strategies for increasing immunization uptake

Telemedicine usage can have unexpected impact on rural communities' access to local care

Age and cultural pressures shape body appreciation among women worldwide

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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