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Vorinostat drives HIV from hiding

The addition of vorinostat to current antiretroviral therapy regimens can potentially help to eradicate hidden pockets of dormant human immunodeficiency virus, according to study results published in Nature.

6 Aug 2012

Manning ICU with 24-hour specialist staff does not improve long-term survival

Having round-the-clock rather than on-demand presence of an intensivist does not increase intensive care unit patients’ long-term survival rates, report US researchers.

6 Aug 2012

Adiposity linked to cognitive decline in elderly

High levels of adiposity increase rates of cognitive decline in the “young elderly” aged between 60 and 70 years, report Korean researchers.

6 Aug 2012

Pendrin a possible new target for diuretic therapy

In patients with fluid overload, inhibition of the chloride-absorbing transporter pendrin and the NaCl co-transporter may provide an effective diuretic regimen without triggering hypokalemia, research suggests.

6 Aug 2012

Boric acid treatment equals best practice for otitis media

Study findings show that a single application of boric acid powder followed by external auditory canal irrigation is as effective as topical ciprofloxacin eardrops for treating active chronic otitis media.

6 Aug 2012

Early CT ‘definitive’ for subarachnoid hemorrhage diagnosis

Cerebrospinal fluid analysis is only necessary for patients with thunderclap headache and a negative computed tomography scan if they undergo imaging more than 6 hours after headache onset, research suggests.

6 Aug 2012

‘Chicken Wing’ clue to stroke risk in atrial fibrillation

Patients with atrial fibrillation who have a Chicken Wing left atrial appendage morphology are less likely to have a stroke than those with other morphologies, research suggests.

6 Aug 2012

New Translational Oncology Program at University of Michigan

The University of Michigan Comprehensive Cancer Center is harnessing its expertise in basic science research to speed the translation into clinical trials and new treatment opportunities for cancer patients.

6 Aug 2012

CPRIT awards $48.2 million in new grants to investigators at UT Southwestern Medical Center

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded $48.2 million in new grants to investigators at UT Southwestern Medical Center to support cancer-related projects and to recruit pre-eminent cancer researchers.

6 Aug 2012

Empa physicist analyzes structure and composition of soot particles

Since June 2012, it is official: The World Health Organisation (WHO) has classified diesel soot as a lung carcinogen. Artur Braun, a physicist at Empa and an X-ray spectroscopy expert, has made crucial contributions to analyzing the structure and composition of soot particles.

6 Aug 2012

New research center to expedite study of gene transfer approach

In an alliance aimed at bringing a new, personalized immunotherapy approach to patients with a wide variety of cancers, the University of Pennsylvania and Novartis announced today an exclusive global research and licensing agreement to further study and commercialize novel cellular immunotherapies using chimeric antigen receptor (CAR) technologies.

6 Aug 2012

Head trauma in older adults over a weekend more deadly than during the week

A Johns Hopkins review of more than 38,000 patient records finds that older adults who sustain substantial head trauma over a weekend are significantly more likely to die from their injuries than those similarly hurt and hospitalized Monday through Friday, even if their injuries are less severe and they have fewer other illnesses than their weekday counterparts.

6 Aug 2012

Astellas announces closure of Urogenix research facility

Astellas Pharma Inc. announced that it decided to close Urogenix, Inc., an Astellas subsidiary, which is a research facility focusing on drug discovery in the field of urology.

6 Aug 2012

UCSF/SFGH report addresses widespread gaps in health literacy and shows how to bridge them

Is it possible for a health care system to redesign its services to better educate patients to deal with their immediate health issues and also become more savvy consumers of medicine in the long run? The answer is yes, according to a study led by scientists at the University of California, San Francisco (UCSF) and San Francisco General Hospital and Trauma Center (SFGH) that was recently reported by the Institute of Medicine (IOM).

6 Aug 2012

Mammalian cells divide when their growth rate hits a specific threshold

It's a longstanding question in biology: How do cells know when to progress through the cell cycle? In simple organisms such as yeast, cells divide once they reach a specific size. However, determining if this holds true for mammalian cells has been difficult, in part because there has been no good way to measure mammalian cell growth over time.

6 Aug 2012

Playfulness may serve an evolutionary role in human mating preferences

Why do adults continue to play throughout their lives while most other mature mammals cease such behavior? According to researchers at Penn State, playfulness may serve an evolutionary role in human mating preferences by signaling positive qualities to potential long-term mates.

6 Aug 2012

Egypt ends use of animals for trauma training program with human-patient simulators from PETA

In a landmark move, Egypt has completely ended the use of animals in its leading trauma training program, thanks to a donation of state-of-the-art TraumaMan human-patient simulators from PETA.

3 Aug 2012

AD hits hardest among people in their 60s and 70s

The greatest risk factor for Alzheimer's disease (AD) is advancing age. By age 85, the likelihood of developing the dreaded neurological disorder is roughly 50 percent. But researchers at the University of California, San Diego School of Medicine say AD hits hardest among the "younger elderly" - people in their 60s and 70s - who show faster rates of brain tissue loss and cognitive decline than AD patients 80 years and older.

3 Aug 2012

Planarian flatworms now a model system for studying eye development and eye diseases

Planarian flatworms have come under intense study for their renowned ability to regenerate any missing body part, even as adults. But now they may take on a starring role as a model system for studying eye development and eye diseases in vertebrates, including humans.

3 Aug 2012

Sta Op Tegen Kanker International Translational Cancer Research Grant recipients announced

Stand Up To Cancer (SU2C) and the Dutch Cancer Society (KWF Kankerbestrijding), along with the American Association for Cancer Research (AACR), SU2C's Scientific Partner, announce the recipients of the Sta Op Tegen Kanker International Translational Cancer Research Grant.

3 Aug 2012