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Skin cell spray key to venous leg ulcer treatment

A spray consisting of a mixture of keratinocyte and fibroblast skin cells holds promise for treatment of venous leg ulcers, show results from a phase II randomized controlled trial published in The Lancet.

3 Aug 2012

Allergy alerts in patient records help improve clinical practice

Allergy alerts in patient records have the potential to significantly improve clinical practice, say Spanish researchers.

3 Aug 2012

Child abuse has repercussions for menarche

Researchers have found an association between childhood abuse and age at menarche onset, they report in the Journal of Adolescent Health.

3 Aug 2012

Alcoholics are often going undiagnosed

Medical staff often do not spot alcohol problems in their patients unless they are already intoxicated, say UK researchers from the University of Leicester.

3 Aug 2012

Corpus callosum abnormalities in BD patients

Patients with bipolar disorder show area reductions in the genu and isthmus subregions of the corpus callosum compared with mentally healthy controls, researchers report.

3 Aug 2012

Self-recognition deficits in schizophrenia confirmed

Patients with schizophrenia exhibit impairments in self-recognition, results from a systematic review and meta-analysis of published studies confirm.

3 Aug 2012

Exercise benefits influenced by sRAGE levels in diabetes

Increased levels of the soluble form of the receptor for advanced glycation end products may underly the beneficial effects of exercise in patients with Type 2 diabetes, research shows.

3 Aug 2012

Patellar length affects tendon contact after posterior-stabilized TKA

In patients undergoing posterior-stabilized total knee arthroplasty, patellar ligament length has the greatest effect on the extent of tendo-femoral contact, say US researchers who have developed a model to aid clinical decision-making.

3 Aug 2012

Potential PD biomarkers identified for sleep behavior disorder

Concomitant olfaction abnormality and increased substantia nigra echogenicity may be preclinical manifestations of parkinsonism in patients with idiopathic rapid eye movement sleep behavior disorder, research suggests.

3 Aug 2012

$Cataract surgery reduces hip fracture, as well as improving eye sight$

Cataract surgery reduces hip fracture, as well as improving eye sight

Surgery for cataract removal significantly reduces the rate of hip fracture in the year after the procedure compared with no surgery, show study results involving over a million Medicare beneficiaries aged over 65 years.

3 Aug 2012

Novel integrase inhibitor dolutegravir shows promise for HIV-1 treatment

The once-daily integrase inhibitor dolutegravir has shown promise in a phase III noninferiority study comparing it with twice-daily raltegravir for treatment of HIV-1, indicate study results presented at the 19th International AIDS Conference in Washington DC, USA.

3 Aug 2012

Home is where the heart is for congenital defect children

The American Heart Association recommends that children with a congenital heart defect deemed as being at high risk for developmental disorders are treated under a “medical home” model of care.

3 Aug 2012

‘Bioactive’ coils disappoint for cerebral aneurysms

The angiographic outcomes of patients in the Cerecyte Coil Trial add to evidence that “bioactive” coils are no better than bare platinum coils in patients with cerebral aneurysms.

3 Aug 2012

‘Fifth link’ improves outcomes after out-of-hospital cardiac arrest

Neurologic outcomes for survivors of out-of-hospital cardiac arrest are significantly improved after implementation of the 2010 American Heart Association's fifth link in the chain-of-survival concept for postresuscitation care, show Japanese study results.

3 Aug 2012

Diabetes impairs women’s sex life

Women with diabetes are less likely to find sex satisfying than those without the condition, despite having similar levels of interest and engagement in sexual activity, show study findings.

3 Aug 2012

Researchers discover surprising and unexpected plasticity in the embryonic endothelium

UCLA stem cell researchers have found for the first time a surprising and unexpected plasticity in the embryonic endothelium, the place where blood stem cells are made in early development.

3 Aug 2012

SAGE Labs, Autism Speaks expand partnership to create first rat models for translational research

Autism Speaks, the world's leading autism science and advocacy organization, today announced its expanded collaboration with Sigma Advanced Genetic Engineering (SAGE) Labs, an initiative of Sigma- Life, to develop the first rat models with modified autism associated genes, intended to accelerate discovery and translational autism research.

3 Aug 2012