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Research highlights guselkumab's impact on Crohn's endoscopic healing

In a major advance for patients with Crohn's disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.

18 Jul 2025

Study identifies SDR42E1's role in vitamin D pathway

Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health: it regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.

18 Jul 2025

Heart failure and atrial fibrillation at the time of mitral valve repair linked to worse outcomes

Patients with heart failure and atrial fibrillation (AF) at the time of mitral transcatheter edge-to-edge repair (M-TEER) for severe mitral regurgitation are more than twice as likely to die or be rehospitalized for heart failure, compared to patients without AF.

18 Jul 2025

Understanding brain activity during sleep to detect early neurological changes

"Complex processes are going on in the brain when we sleep," says Dr Karolina Armonaitė, a neuroscientist from Kaunas University of Technology, Lithuania. According to her, a more precise understanding of what happens in different areas of the cerebral cortex during sleep can help diagnose sleep disorders and neurological diseases more accurately.

18 Jul 2025

Urban development and socioeconomic status drive dengue hotspots in Medellín

A new study led by researchers from the University of Eastern Finland and a team of international collaborators shows that dengue outbreaks in Medellín, Colombia, are strongly linked to patterns of urban development and socioeconomic status.

18 Jul 2025

Exploring the genetic link between COPD and abdominal aortic aneurysm

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Chronic obstructive pulmonary disease (COPD) and abdominal aortic aneurysm (AAA) are both severe conditions with complex etiologies and substantial comorbidities.

18 Jul 2025

GLP-1 weight-loss drugs are reshaping modern dating and intimacy

GLP-1 weight-loss drugs are changing how people date and connect. In a nationally representative survey of 2,000 single U.S. adults (ages 18 to 91) led by the Kinsey Institute at Indiana University with DatingNews.com, GLP-1 users reported a wide range of physical, social, and psychological shifts they attributed to the drug.

18 Jul 2025

Retrospective analyses indicate Ozempic’s protective effects against stroke fatality

Three studies presented today at the Society of NeuroInterventional Surgery's (SNIS) 22nd Annual Meeting discussed whether using GLP-1 inhibitors could lessen the impacts of stroke and related brain injuries or reduce the risk of stroke altogether.

18 Jul 2025

New insights into brain fueling could lead to treatments for stroke, neurodegeneration

A new Yale study has revealed that neurons - the energy-hungry cells that connect and direct activity in the brain - are equipped with "backup batteries" that kick in to keep the brain running during periods of metabolic stress.

18 Jul 2025

Human eggs use a minimalist strategy to stay healthy for decades

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published today in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal systems as they mature, most likely an evolutionary design which keeps metabolism low and damage at bay.

18 Jul 2025

Heart scarring linked to abnormal rhythms in older male endurance athletes

Scar tissue in the heart was associated with abnormal heart rhythms among healthy, long-time male endurance athletes age 50 or older, potentially increasing their risk of sudden cardiac death, according to a small study published today in Circulation: Cardiovascular Imaging, an American Heart Association journal.

18 Jul 2025

Chronic venous insufficiency linked to increased cardiovascular disease and mortality risk

In light of reports from the White House that President Donald J. Trump has been diagnosed with Chronic Venous Insufficiency (CVI), the American Heart Association is sharing important information on the condition and its association with cardiovascular risk factors, disease and increased risk of death.

18 Jul 2025

PAR1 protein found to boost lung fluid drainage during injury

A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine.

18 Jul 2025

Social media use linked to declining focus and emotional strain in youth

The use of social media is contributing to declining attention spans, emotional volatility, and compulsive behaviors among young people, reveals a new report by Nanyang Technological University, Singapore (NTU Singapore) and Singapore-based research agency Research Network, in collaboration with US-based AI platform ListenLabs.ai.

18 Jul 2025

Climate disasters threaten malaria control efforts in high-burden regions

Tropical cyclones in Madagascar lead to sharp spikes in malaria infections – particularly in children – due to interruptions in control efforts, according to a new study.

17 Jul 2025

Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

17 Jul 2025

Uncovering a protective RNA molecule in kidney stress and disease

Cells contain helper molecules called transfer RNAs (tRNAs), which carry building blocks (amino acids) to make proteins.

17 Jul 2025

Challenges in identifying high risk patients for preeclampsia using USPSTF guidelines

Preeclampsia (PE) is a hypertensive disease that complicates 7-10% of pregnancies. While recent advances in understanding the underlying causes of PE have been made, predicting its occurrence has historically been difficult because it is a complex condition that likely results from a variety of causes and can present in different ways.

17 Jul 2025

Study casts doubt on a widely used shortcut in rectal cancer drug trials

A new study by a Tulane University researcher casts doubt on a widely used shortcut in rectal cancer drug trials, raising concerns that some treatments may be fast-tracked for approval without evidence they help patients live longer.

17 Jul 2025

New surgical method could become an alternative for treating groin hernias in women

In a study conducted in Uganda and published in JAMA Surgery, researchers from Karolinska Institutet evaluated a new surgical method for treating groin hernias in women.

17 Jul 2025