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Underappreciated set of enzymes connected to the regulation of hippo pathway in cancer

Within the family of cell membrane lipids known as phosphoinositides and the kinase enzymes that regulate them, phosphoinositide 3-kinases (PI3Ks) have been cast in a starring role as scientists study their involvement in cancer, diabetes and many cellular activities.

28 May 2024

Research reveals loneliness as a complex interplay of social impairments, oxytocin, and illness

A recent review in the journal Neuroscience & Biobehavioral Reviews presents a multidimensional model of loneliness, exploring its impact on social interactions, the oxytocin system, and illness. The study emphasizes the need for multidisciplinary collaboration to understand and address loneliness effectively.

28 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Novel coating in antipsychotics mitigates unwanted weight gain and boosts serotonin levels

Thousands of Australians struggle with serious mental health conditions. But when the recommended treatment involves antipsychotic medications, the side effects are excess kilos, which only adds weight to an already complex diagnosis.

28 May 2024

Simple vaginal swab could help detect early-stage gynecological cancers

A simple vaginal swab could reveal the presence of early-stage gynecological cancers, according to a new, wide-ranging study published in De Gruyter's Open Life Sciences.

28 May 2024

Johns Hopkins researchers propose a novel approach to addressing kidney donor shortage

Researchers from Johns Hopkins Medicine propose a novel approach to addressing the pressing issue of a kidney donor shortage through findings that suggest a promising method to expand the pool of available kidney donors by utilizing deceased donors on dialysis for kidney transplants.

28 May 2024

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

28 May 2024

New point-of-care test revolutionizes toxoplasmosis screening

An inexpensive, accurate test that detects infections with the parasite Toxoplasma gondii can provide results within 30 minutes from a finger-prick in a doctor's office or within an hour from a small blood sample tested in a local medical laboratory.

28 May 2024

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy.

28 May 2024

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

A University of Saskatchewan (USask) research team's discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new avenues for treating obesity and metabolic disorders in animals and people.

28 May 2024

New meta-analysis supports omega-3 supplementation for aggression reduction

People who regularly eat fish or take fish oil supplements are getting omega-3 fatty acids, which play a critical role in brain function.

28 May 2024

New subset of T cells may enhance cancer immunotherapy

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

28 May 2024

Prenatal air pollution exposure linked to adolescent mental health problems

A baby's exposure to air pollution while in the womb is associated with the development of certain mental health problems once the infant reaches adolescence, new research has found.

28 May 2024

Novel light-sensitive drug induces sleep without genetic modification

The nucleus accumbens plays a pivotal role in motivational behavior and sleep regulation, modulated by adenosine A2A receptors (A2AR).

28 May 2024

High caffeine consumption linked to changes in dopamine function in Parkinson's patients

Regular high caffeine consumption affects dopamine function in patients with Parkinson's disease, shows a new international study led by the University of Turku and Turku University Hospital in Finland.

28 May 2024

Binge-eating disorder persists longer than previously thought, study shows

Binge-eating disorder is the most prevalent eating disorder in the United States, but previous studies have presented conflicting views of the disorder's duration and the likelihood of relapse.

28 May 2024

Strategies for addressing disease X and enhancing global health security

Announcing a new article publication for Zoonoses journal. Disease X stands as a symbol for a subset of emerging infectious diseases rising to prominence as a significant challenge to global health security.

28 May 2024

Study uncovers probable origin of stuttering in the brain

An international research group led by researchers from the University of Turku and Turku University Hospital in Finland has succeeded in identifying the probable origin of stuttering in the brain.

28 May 2024

Oral semaglutide shows promising results for type 2 diabetes in routine clinical settings

Semaglutide and its effects on glycemic control, body weight (BW), and tolerability in routine clinical practice.

28 May 2024

Research highlights positive impact of yoga and mediterranean diet on elderly health

The combined effects of yoga and the Mediterranean diet (MD) on various health outcomes in community-dwelling older adults.

28 May 2024

Medical Research News

Underappreciated set of enzymes connected to the regulation of hippo pathway in cancer

Research reveals loneliness as a complex interplay of social impairments, oxytocin, and illness

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Novel coating in antipsychotics mitigates unwanted weight gain and boosts serotonin levels

Simple vaginal swab could help detect early-stage gynecological cancers

Johns Hopkins researchers propose a novel approach to addressing kidney donor shortage

Understanding the link between EBV-infected B cells and multiple sclerosis

New point-of-care test revolutionizes toxoplasmosis screening

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

New meta-analysis supports omega-3 supplementation for aggression reduction

New subset of T cells may enhance cancer immunotherapy

Prenatal air pollution exposure linked to adolescent mental health problems

Novel light-sensitive drug induces sleep without genetic modification

High caffeine consumption linked to changes in dopamine function in Parkinson's patients

Binge-eating disorder persists longer than previously thought, study shows

Strategies for addressing disease X and enhancing global health security

Study uncovers probable origin of stuttering in the brain

Oral semaglutide shows promising results for type 2 diabetes in routine clinical settings

Research highlights positive impact of yoga and mediterranean diet on elderly health

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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