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Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.

9 May 2024

Experts identify highly drug-resistant infections from stem cell treatments In Mexico

Experts in mycobacterial diseases at National Jewish Health, in collaboration with local health departments and the Centers for Disease Control and Prevention (CDC), are investigating a potential outbreak of a highly drug-resistant mycobacterium (germ) after U.S. patients who traveled to Mexico for stem cell injections became sick.

9 May 2024

Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation

Modified ketogenic diet modulates gut microbiome, inflammatory markers, and brain-related miRNAs in autistic children, correlating with improved behavioral symptoms. The diet increases beneficial gut bacteria and reduces inflammatory cytokines and BDNF levels.

9 May 2024

Researchers unveil digital 'alcohol twin' to predict drinking risks and guide personalized interventions

Digital twin model simulates real-life alcohol consumption patterns and links them to long-term biomarkers, aiding eHealth strategies to curb dangerous drinking habits. The model captures complex physiological interactions between food, beverages, and alcohol metabolism.

9 May 2024

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.

9 May 2024

Study examines association between neighborhood disadvantage and DNA methylation in brain tissue

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "The association between neighborhood deprivation and DNA methylation in an autopsy cohort."

9 May 2024

Mouse-rat chimeras offer functional liver cells for transplantation

Liver disease, due to viral infections, alcohol abuse, obesity, or cancer, accounts for 1 in every 25 deaths worldwide.

9 May 2024

Exploring microbiome dynamics in esophageal cancer

Esophageal cancer (EC) has two primary subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC).

9 May 2024

Longitudinal antibody changes key to identifying peanut allergy resolution in kids

Australian researchers have discovered how changes in antibody levels over time can predict which children are likely to outgrow their peanut allergy.

9 May 2024

Enhancing the ability of natural killer cells to combat hematologic malignancies

A new study reveals a groundbreaking approach to immunotherapy, demonstrating that blocking the interaction between the CD300A receptor and phosphatidylserine (PS) significantly enhances the ability of human natural killer (NK) cells to lyse hematologic malignancies (HMs).

9 May 2024

Study uncovers sex-based disparities in liver transplant survival rates

Liver transplantation is a life-saving option for those with hepatocellular carcinoma (HCC), the most prevalent type of liver cancer.

9 May 2024

Understanding aging through stochastic changes in cells

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth.

9 May 2024

Research shows the impact of social deprivation and distance on pulmonary fibrosis survival

Patients with pulmonary fibrosis from the poorest areas had more severe symptoms by the time they saw a hospital doctor and had a poorer survival rate than those living in wealthier areas, according to the new research.

9 May 2024

New tool leverages AI to predict suicidal thoughts and behaviors

A new assessment tool that leverages powerful artificial intelligence was able to predict whether participants exhibited suicidal thoughts and behaviors using a quick and simple combination of variables.

9 May 2024

Oral rinse shows promise in early detection of gastric cancer

A simple oral rinse could provide early detection of gastric cancer, the fourth-leading cause of cancer deaths worldwide, according to a study scheduled for presentation at Digestive Disease Week (DDW) 2024.

9 May 2024

Innovative endoscopic treatment targets hunger hormone for weight loss

A new weight-loss treatment could be on the horizon with an innovative endoscopic procedure that ablates (burns) the stomach lining to reduce production of ghrelin, a hormone that triggers hunger, resulting in decreased appetite and significant weight loss, according to a first-in-human trial to be presented at Digestive Disease Week (DDW) 2024.

9 May 2024

Study shows steep rise in colorectal cancer among younger populations

Colorectal cancer incidence has steadily increased among younger people in the U.S. over the last two decades, with the youngest seeing the most dramatic jumps, according to a study scheduled for presentation at Digestive Disease Week (DDW) 2024.

9 May 2024

Study reveals altered protein rhythms linked to metabolic disorders in night shift workers

Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions.

9 May 2024

UT Health San Antonio leads effort for developing oral vaccine against chlamydia

The study of a novel oral vaccine that could protect against chlamydia infection has been awarded approximately $11 million in National Institutes of Health funding over five years through a cooperative agreements research project grant, known as a U01 grant.

9 May 2024

Researchers discover potential new treatment for alopecia areata

Researchers at MIT, Brigham and Women's Hospital, and Harvard Medical School have developed a potential new treatment for alopecia areata, an autoimmune disorder that causes hair loss and affects people of all ages, including children.

9 May 2024

Medical Research News

Combination immunotherapy treatment enhances immune response for people with malignant gliomas

Experts identify highly drug-resistant infections from stem cell treatments In Mexico

Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation

Researchers unveil digital 'alcohol twin' to predict drinking risks and guide personalized interventions

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Study examines association between neighborhood disadvantage and DNA methylation in brain tissue

Mouse-rat chimeras offer functional liver cells for transplantation

Exploring microbiome dynamics in esophageal cancer

Longitudinal antibody changes key to identifying peanut allergy resolution in kids

Enhancing the ability of natural killer cells to combat hematologic malignancies

Study uncovers sex-based disparities in liver transplant survival rates

Understanding aging through stochastic changes in cells

Research shows the impact of social deprivation and distance on pulmonary fibrosis survival

New tool leverages AI to predict suicidal thoughts and behaviors

Oral rinse shows promise in early detection of gastric cancer

Innovative endoscopic treatment targets hunger hormone for weight loss

Study shows steep rise in colorectal cancer among younger populations

Study reveals altered protein rhythms linked to metabolic disorders in night shift workers

UT Health San Antonio leads effort for developing oral vaccine against chlamydia

Researchers discover potential new treatment for alopecia areata

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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