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Study reveals hidden cause of treatment failure in acute promyelocytic leukemia

Researchers at Zhejiang University School of Medicine have identified a single point mutation in the normal PML gene that can block the effect of arsenic trioxide, a frontline drug for acute promyelocytic leukemia.

4 Jul 2025

Physician associates found effective under supervision but pose risks in unsupervised care

Physician associates provide safe and effective care when they work under the direct supervision of doctors and care for patients who have already been diagnosed, or when they undertake procedures for which they have been highly trained, finds a rapid review published in The BMJ today.

4 Jul 2025

XPR1 silencing enhances immune response and reduces ovarian tumor growth

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I expression.

4 Jul 2025

EMP1 identified as key driver of tumor progression in resectable pancreatic cancer

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the associated factor EMP1 in the progression of resectable pancreatic cancer (PC).

4 Jul 2025

Chemist awarded NSF grant to study DNA nanoparticles for gene therapy

Case Western Reserve University chemist Divita Mathur was awarded a National Science Foundation (NSF) Faculty Early Career Development Program (CAREER) grant for her research in synthetic DNA nanoparticles, which have potential applications in gene therapy.

4 Jul 2025

Herbal extract from Caryota maxima extends lifespan through lipid metabolism

Announcing a new publication for Acta Materia Medica journal. Geroprotectors that delay aging have substantial potential for preventing and mitigating age-related diseases.

4 Jul 2025

Flawed coronavirus model prompts urgent reassessment for drug developers

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections.

4 Jul 2025

Rare kidney cancer evades immune system in unique ways

Cancer fighting T-cells, the immune system's primary enforcers, are scarce in the rare kidney cancer called chromophobe renal cell carcinoma (ChRCC) and those that are present are indifferent to the tumor threat and traditional immune therapies, revealing the need for new targets and treatments.

4 Jul 2025

Real time imaging reveals how visual experience rewires the brain

Scientists have long known that the brain's visual system isn't fully hardwired from the start-it becomes refined by what babies see-but the authors of a new MIT study still weren't prepared for the degree of rewiring they observed when they took a first-ever look at the process in mice as it happened in real-time.

4 Jul 2025

Hearing aids and cochlear implants improve social lives of adults with hearing loss

Hearing loss doesn't just affect how people hear the world - it can also change how they connect with it.

4 Jul 2025

AI assistance improves accuracy and consistency in skin cancer tissue analysis

Pathologists' examinations of tissue samples from skin cancer tumors improved when they were assisted by an AI tool. The assessments became more consistent and patients' prognoses were described more accurately.

4 Jul 2025

Research highlights an increase in informal use of doxyPEP/PrEP among key populations in the Netherlands

New research analyzing an online survey of 1,633 respondents found 15% recent use of doxycycline post- and pre-exposure prophylaxis (doxyPEP/PrEP) among men who have sex with men (MSM), transgender and gender diverse people in the Netherlands according to a recent study published by Eurosurveillance.

4 Jul 2025

Restoring neuron balance in the amygdala reverses anxiety in mice

The Synaptic Physiology laboratory, led by Juan Lerma at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University (UMH) of Elche, has discovered that a specific group of neurons in the amygdala, a brain region involved in emotion regulation, plays a key role in the emergence of conditions such as anxiety, depression, and altered social behavior.

4 Jul 2025

$Ten-year study tracks trends in pediatric clavicle fractures across the U.S.$

Ten-year study tracks trends in pediatric clavicle fractures across the U.S.

Clavicular fractures are common injuries among children, usually due to sports-related trauma or accidental falls. The purpose of this study was to assess the epidemiology of clavicular fractures among children in the United States between 2014 and 2023.

4 Jul 2025