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Wastewater clues could revolutionize Alzheimer's detection

Review explores the potential of wastewater-based epidemiology (WBE) for diagnosing Alzheimer's disease (AD) through biomarkers in biofluids, offering a non-invasive, cost-effective approach to early detection and large-scale monitoring.

18 Feb 2024

New study pinpoints key markers for Long COVID diagnosis

Study identifies elevated serologic responses and memory CD8+ T cell clonal expansion as key markers of Long COVID, offering insights into its pathology and potential diagnostic approaches.

18 Feb 2024

Pilates lowers blood pressure in hypertensive patients, study finds

Pilates training programs are deemed safe and effective for managing blood pressure in hypertensive patients, offering a viable rehabilitation option alongside traditional treatments.

18 Feb 2024

Exome sequencing unravels complex genetic diagnoses in growth disorders

In an article published in the Journal of Pediatrics, researchers based in Brazil describe the case of a nine-year-old boy admitted to hospital with multiple symptoms and overlapping conditions that made diagnosis difficult, such as short stature, thin tooth enamel (dental enamel hypoplasia), moderate mental deficiency, speech delay, asthma, mildly altered blood sugar, and a history of recurring infections in infancy.

16 Feb 2024

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

16 Feb 2024

Rabies in urban opossums signals health alert in São Paulo

A female White-eared opossum (Didelphis albiventris) found dead in 2021 in Bosque dos Jequitibás Park in the center of Campinas, one of the largest cities in São Paulo state, Brazil, died from rabies meningoencephalitis, according to a group of researchers at the University of São Paulo (USP) and Adolfo Lutz Institute (IAL), the regional reference laboratory, working with health professionals affiliated with public institutions in São Paulo city and Campinas.

16 Feb 2024

Risk-reducing mastectomies lower breast cancer incidence and mortality in BRCA variant carriers

A study co-led by Professor Kelly Metcalfe of the Lawrence Bloomberg Faculty of Nursing, and researchers at the Familial Breast Cancer Research Unit at Women's College Hospital, finds risk-reducing mastectomies (RRM) in women with a BRCA1 or BRCA2 genetic variant, significantly reduces the risk of being diagnosed with breast cancer and lowers the probability of death.

16 Feb 2024

Optimizing chemotherapy for older adults with advanced cancer

Standard chemotherapy regimens, which are mostly based on testing in relatively young and healthy patients, may do more harm to older adults with cancer who often struggle with other health issues.

16 Feb 2024

Unlocking the brain's decision-making secrets for future insights

Researchers at Washington University School of Medicine in St. Louis have found important clues to how people make choices involving obtaining information about the future.

16 Feb 2024

FDA approves omalizumab for food allergy reactions based on NIH research

Today's Food and Drug Administration approval of a supplemental biologics license for the monoclonal antibody omalizumab (Xolair) highlights the vital role of the National Institutes of Health-supported research that underpins the FDA decision.

16 Feb 2024

Lockdown delays in melanoma diagnosis cost Europe £6bn and thousands of lives

Delays in diagnosing melanoma due to Covid-19 lockdown may have contributed to over 100,000 years of life lost across Europe and over £6bn in costs, mainly indirectly due to loss of productivity, finds a new study led by UCL and University Hospital of Basel researchers.

16 Feb 2024

Study links finger length ratio to oxygen metabolism efficiency in athletes

The efficiency of oxygen supply to tissues is a factor in the severity of important diseases such as Covid-19 and heart conditions.

16 Feb 2024

New standards for evaluating aging biomarkers unveiled

A new paper led by Harvard researchers has zeroed in on biomarkers of aging using omic data from population-based studies.

16 Feb 2024

Innovative immunotherapy targets rare melanoma subtypes

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma.

16 Feb 2024

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

Although primary open-angle glaucoma (POAG) is the leading cause of blindness in people over the age of 55, there remains no cure for the disease and its biological mechanisms are not well understood.

16 Feb 2024

Neoadjuvant chemotherapy shows promise for advanced penile cancer

Penile squamous cell carcinoma is a rare malignancy with limited treatment options and poor prognosis, especially in advanced stages. Because of its rarity, few studies focus on better understanding and managing this disease.

16 Feb 2024

Study suggests patients with severe long COVID present with variable symptoms, do not cluster in relation to organs affected or immunological states

A new preprint reports significantly associated findings that may help predict severe long COVID and understand what causes it.

16 Feb 2024

Researchers discover protein key to toxoplasmosis pathogen multiplication

Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.

16 Feb 2024

Risk of non-alcoholic fatty liver disease for cardiovascular disease and all cause death in patients with type 2 diabetes mellitus

Researchers investigated the link between non-alcoholic fatty liver disease in individuals with type 2 diabetes mellitus (T2DM) and all-cause death and cardiovascular disease.

16 Feb 2024

COVID-19 impacts the brain through body inflammation, research finds

Scientists still are not sure how neurological symptoms arise in COVID-19. Is it because SARS-CoV-2 infects the brain? Or are these symptoms the result of inflammation in the rest of the body?

16 Feb 2024