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Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Researchers used deep mutational scans to measure the effect of each amino-acid mutation in the receptor-binding domain of SARS-CoV-2 Wuhan-Hu-1, Alpha, Beta, Delta, and Eta variants.

1 Mar 2022

Effectiveness of Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing severe SARS-CoV-2 infection

A new study compared the effectiveness of the Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing SARS-CoV-2 infections.

1 Mar 2022

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

In a new study, researchers evaluated the immune responses induced by the mRNA-based SARS-CoV-2 vaccination against SARS-CoV-2 variants in multiple myeloma patients.

1 Mar 2022

Novel coronavirus identified in Swedish bank voles

Researchers recently discovered a new coronavirus, named Grimso virus, in Swedish bank voles, using samples collected between 2015 and 2017.

1 Mar 2022

Estimating life expectancy changes since 2020

Researchers investigated LE in 29 countries, including most European countries, Chile, and the USA, in 2021.

1 Mar 2022

Study identifies olfactory dysfunction as an early symptom of COVID-19

In a new study, scientists researched olfactory loss and dysfunction among COVID-19 patients to objectively characterize it as a symptom of COVID-19.

1 Mar 2022

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Researchers found that an antiviral drug, was effective against SARS-CoV-2 variants, including the recently emerged Omicron variant, in Syrian hamsters.

1 Mar 2022

Study proposes structural explanation for immune evasion effect of SARS-CoV-2 BA.2 variant mutations S371L/F

Researchers proposed a structural mechanism to explain immune evasion effects of the two-point mutations, S371L and S371F, in the receptor-binding domain of the SARS-CoV-2 Omicron variant.

1 Mar 2022

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Researchers investigated protein interactions of SARS-CoV-2 with host and viral RNAs in infected cells.

1 Mar 2022

Study reveals how the immune system can be triggered to attack cancer cells

New research from the University of East Anglia and Quadram Institute reveals how our immune system can be triggered to attack cancer cells.

1 Mar 2022

Doing less exercise could deactivate a vital protein in the body, suggests study

Doing less exercise could deactivate a vital protein in the body, causing further inactivity and making exercise more difficult, new research suggests.

1 Mar 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

Researchers study cell infection and viral replication methods affected by SARS-CoV-2 mutations through a novel respiratory model.

28 Feb 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Ever noticed that looking at photos of good times with family or friends diminishes the pain of your headache? Nostalgia has already been shown to be helpful with pain relief, and a new study has now revealed the thalamocortical mechanism for nostalgia-induced analgesia.

28 Feb 2022

Research shows intergenerational effects of preconception opioids in male offspring rats

New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy - even if not used during pregnancy itself - could result in a higher likelihood that a mother's male offspring will develop type 2 diabetes and metabolic syndrome, conditions that increase the risk of heart disease and stroke.

28 Feb 2022

Scientists investigate the antiviral properties of cow milk protein against SARS-CoV-2 variants

As the COVID-19 pandemic continues to claim lives around the world, dairy scientists may have a surprising role to play. In a new report published in the Journal of Dairy Science, scientists from the University of Michigan (Ann Arbor, MI, USA) and Glanbia PLC Research and Development (Twin Falls, ID, USA) have collaborated to investigate the antiviral properties of cow milk protein against variants of SARS-CoV-2, the virus behind the illness.

28 Feb 2022

Medical Science News

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Effectiveness of Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing severe SARS-CoV-2 infection

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

Novel coronavirus identified in Swedish bank voles

Estimating life expectancy changes since 2020

Study identifies olfactory dysfunction as an early symptom of COVID-19

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Study proposes structural explanation for immune evasion effect of SARS-CoV-2 BA.2 variant mutations S371L/F

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Study reveals how the immune system can be triggered to attack cancer cells

Doing less exercise could deactivate a vital protein in the body, suggests study

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

A study on the evolution of avian coronavirus escape mutants in vitro

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Research shows intergenerational effects of preconception opioids in male offspring rats

Scientists investigate the antiviral properties of cow milk protein against SARS-CoV-2 variants

Understanding the gut microbiome could help personalize immunotherapy for melanoma

Study reveals new way viruses trigger autoimmunity

Researchers create model to explore SARS-CoV-2 Omicron and Delta supremacy

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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