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Pregnant women with COVID-19 are more susceptible to pre-eclampsia

A review of the scientific literature published by Brazilian researchers shows that pregnant women infected by the novel coronavirus run a higher risk of developing pre-eclampsia, a pregnancy complication characterized by persistent high blood pressure, usually in the second half of pregnancy or shortly after delivery.

26 Aug 2021

Preliminary study suggests nitric oxide may be a potential treatment for COVID-19 respiratory failure

New research led by Devang K. Sanghavi of the Mayo Clinic in Florida, USA, suggests pre-intubation use of nitric oxide for patients with COVID-19–related hypoxemic respiratory may help reduce patients' mortality. Their findings show that inhaling nitric oxide in this patient population could reduce the need for future intubation and other invasive mechanical ventilation.

26 Aug 2021

German study shows high protection from COVID-19 in over 80s with Pfizer vaccine

A new observational study in Germany, recently published on the medRxiv* preprint server, found the Comirnaty vaccine to be 68.3% effective against COVID-19 for people over 80. In those fully immunized, the vaccine was found to be 73.2% effective in preventing hospitalization and 80.1% effective against death.

26 Aug 2021

Oral mucosa identified as potential target for SARS-CoV-2 infection

A recent study suggested that ACE2 receptors are expressed in oral tissues, making the oral cavity an important potential entry point of SARS-CoV-2.

26 Aug 2021

Aging reduces the risk of developing genetically related diseases

Unexpected findings provide insights into how aging and genetically determined diseases are associated.

26 Aug 2021

Migraines may hold the key to new treatment for diabetes

The mechanistic association between migraines and type 2 diabetes reveals a new approach to treat diabetes.

26 Aug 2021

Potential variant of interest in South Africa assigned to the PANGO lineage C.1.2

Continual genomic surveillance of the SARS-CoV-2 strains in South Africa has revealed an increase in the number of sequences belonging to C.1 lineage during the third wave (May 2021) of SARS-CoV-2 infections. This observation was unexpected because C.1 was last reported in January 2021.

26 Aug 2021

The influence of COVID-19 on platelet activation and aggregation

In a paper recently uploaded to the bioRxiv* preprint server, humanized ACE2 mice are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and platelets are subsequently isolated from the blood for quantitative proteomic analysis.

26 Aug 2021

Scientists assess SARS-CoV-2 mutants in ferret hosts

In a paper recently uploaded to the preprint server bioRxiv* by the cause of SARS-CoV-2 mutations observed in mink and ferrets is investigated, and the danger posed by such mutations to humans assessed.

26 Aug 2021

Two mRNA vaccines are effective even without post-shot symptoms or prior SARS-CoV-2 infection

Vaccination with the two messenger RNA (mRNA) vaccines for SARS-CoV-2, the virus that causes COVID-19, yields a robust antibody response, even if a person did not develop significant symptoms following vaccination or did not have a prior SARS-CoV-2 infection.

26 Aug 2021

Researchers identify potential new treatment for osteoarthritis

Osteoarthritis (OA) is a debilitating joint disease that affects millions of individuals worldwide. Common in the older adult population, OA is associated with loss of cartilage over time.

26 Aug 2021

Research offers new insight into how to treat endometriosis

Endometriosis is a painful, chronic condition in which tissue from the uterus inappropriately grows outside the uterus.

26 Aug 2021

Athletes with history of concussions may show subtle and chronic brain changes

A new study suggests athletes with a history of concussion may show more brain injury from a later concussion, particularly in middle regions of the brain that are more susceptible to damage, when compared to athletes with no history of concussion.

26 Aug 2021

Motor control in older adults may be exacerbated by age-related executive functioning decline

Aging-US published "Cognition and action: a latent variable approach to study contributions of executive functions to motor control in older adults" which reported that Aging is associated with profound alterations in motor control that may be exacerbated by age-related executive functioning decline.

26 Aug 2021

An existing drug may function as targeted therapy for ALL in children

A new study from Linköping University has shown that the tumour-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children.

25 Aug 2021

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

In recent years, immune-based treatments for cancer have buoyed the hopes of doctors and patients alike. Drugs called immune checkpoint inhibitors have provided lifesaving benefits to a growing list of people with several types of cancer, including melanoma, lung cancer, bladder cancer, and many more.

25 Aug 2021

CIRM approves a trio of awards for new stem cell-based projects

The governing Board of the California Institute for Regenerative Medicine has approved a trio of awards, totaling approximately $4 million, to University of California San Diego School of Medicine researchers to advance studies of new stem cell-based treatments for multiple types of cancer and amyotrophic lateral sclerosis (ALS).

25 Aug 2021

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, according to a study published in the journal Clinical Cancer Research.

25 Aug 2021

Researchers identify mechanism for formation of rare colorectal cancer subtype

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, recently discovered a mechanism to explain what drives the formation of mucinous colorectal adenocarcinoma (MAC), a rare subtype of colorectal cancer (CRC), and has also identified the genes responsible for the regulation of this mechanism.

25 Aug 2021

Wake Forest and AFAR receive up to $5 million NIA renewal award to continue management of RCCN

Wake Forest School of Medicine and the American Federation for Aging Research have received a renewal award for up to $5 million over five years from the National Institute on Aging, National Institutes of Health, to continue their management of the Research Centers Collaborative Network.

25 Aug 2021