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Caspase-11 identified as regulator of inflammatory pathology in SARS-CoV-2 infections

New findings identify CASP4/11 as detrimental to inflammation and coagulopathy associated with SARS-CoV-2 infection.

28 Sep 2021

Scientists create new compliance-based model for SARS-CoV-2 transmission

Researchers from Utrecht University have been investigating the interactions between compliance social distance measurements, infection, and vaccination coverage in order to inform public health policy further. A research paper covering their work is available on the medRxiv* preprint server.

28 Sep 2021

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Researchers from the University of Oxford and the University of Warwick have collaborated to develop a method to better understand and evaluate these pleiomorphisms.

28 Sep 2021

Novel optogenetic implant controls activity of neurons in the spinal cord

Grégoire Courtine doesn't hesitate to use the word "revolutionary" when describing the emerging field of optogenetics – a technology that uses pulses of light to control individual neural activity – and what it could mean for neuroscience. Courtine, director of the NeuroRestore research center (with neurosurgeon Jocelyne Bloch), is currently developing an optogenetic implant together with Stéphanie Lacour, who holds the Bertarelli Foundation Chair in Neuroprosthetic Technology.

28 Sep 2021

Researchers release guidance to address pathology aspects in clinical trial protocols

An international group of cancer researchers, led by the National Cancer Research Institute's (NCRI) Cellular Molecular Pathology Initiative (CMPath), has published guidance to address the variability in how pathology is planned and delivered in clinical trials.

28 Sep 2021

Researchers develop fast, low-energy artificial synapse for advanced AI systems

Brain-inspired computing is a promising candidate for next-generation computing technologies. Developing next-generation advanced artificial intelligence (AI) systems that can be as energy-efficient, lightweight, and adaptable as the human brain has attracted significant interest.

28 Sep 2021

COVID Moonshot receives key funding to accelerate drug discovery efforts

The COVID Moonshot, a non-profit, open-science consortium of scientists from around the world dedicated to the discovery of globally affordable and easily-manufactured antiviral drugs against COVID-19 and future viral pandemics has received key funding of £8 million from Wellcome, on behalf of the Covid-19 Therapeutics Accelerator.

28 Sep 2021

New discovery greatly improves detection of HPV in the bloodstream

Princess Margaret Cancer Centre researchers have made new findings which greatly improve detection of the human papillomavirus (HPV) in the bloodstream and could further hone precision treatment of the illness.

27 Sep 2021

Brain communication networks altered during drug withdrawal, mice study shows

Zeroing in on specific brain regions when studying drug and alcohol abuse simplifies research but may leave out important insights.

27 Sep 2021

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

A new type of targeting chaperon protein HSP70 inhibitor QL47 was recently discovered by a team led by Prof. LIU Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences to treat FLT3-ITD-positive acute myeloid leukemia (AML).

27 Sep 2021

Enterovirus 71 vaccine candidate strains exhibit good immunogenicity and cross-neutralization activity

Announcing a new article publication for Zoonoses journal. In this commentary researchers from Beijing Minhai Biotechnology Co., Ltd., Beijing, China, Hubei Provincial Center for Disease Control and Prevention, Wuhan, China, Guangdong Provincial Institute of Biological Products and Drugs, Guangzhou, China, Gaozhou Center for Disease Control and Prevention, Guangdong, China and the Yangchun Center for Disease Control and Prevention, Guangdong, China consider immungenicity and cross-neutralizing activity of enterovirus 71 vaccine candidate strains.

27 Sep 2021

Researchers identify key molecules that may help combat inflammatory diseases

For the first time, researchers have identified key molecules within the immune system that may help fight the inflammation that drives chronic diseases including cancers, sepsis and brain disease.

27 Sep 2021

An in-depth assessment into origin and spread of SARS-CoV-2 Delta variant in Brazil

Brazilian researchers characterize the dissemination of the Delta VOC in Brazil and assess its emergence within the global Delta phylogeny.

27 Sep 2021

Third COVID-19 mRNA vaccine booster dose indicated for myelofibrosis patients

A new study discusses the utility of a third booster dose in patients with myelofibrosis.

27 Sep 2021

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

New research from Johns Hopkins Kimmel Cancer Center investigators shows why some drugs in clinical trials for treating a form of acute myeloid leukemia (AML) often fail and demonstrates a way to restore their effectiveness.

27 Sep 2021

Chronic COVID-19 and divergent variants of SARS-CoV-2

A new study discusses the isolation of two variants of concern (VOCs) from an immunocompromised COVID-19 patient.

27 Sep 2021

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

A new review article investigates the clinical and viral characteristics, pathogenesis, as well as human genetic basis associated with COVID-19.

27 Sep 2021

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

Addictive psychostimulants, from nicotine in cigarettes to illicit drugs like methamphetamine and cocaine, affect different regions of the brain. The same is believed true during withdrawal; finding a common brain pathway has proved elusive.

27 Sep 2021

$6 million CDC grant to support U-M researchers in reducing youth firearm violence

Middle- and high school-age children across the United States are more likely to die as the result of a firearm injury than from any other single cause of death.

27 Sep 2021

Limited evidence colchicine reduces COVID-19 related hospitalization

The present randomized clinical trial attempted to study if colchicine will effectively hasten recovery and reduce COVID-19 associated hospitalizations or death.

27 Sep 2021

Medical Science News

Caspase-11 identified as regulator of inflammatory pathology in SARS-CoV-2 infections

Scientists create new compliance-based model for SARS-CoV-2 transmission

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Novel optogenetic implant controls activity of neurons in the spinal cord

Researchers release guidance to address pathology aspects in clinical trial protocols

Researchers develop fast, low-energy artificial synapse for advanced AI systems

COVID Moonshot receives key funding to accelerate drug discovery efforts

New discovery greatly improves detection of HPV in the bloodstream

Brain communication networks altered during drug withdrawal, mice study shows

Scientists discover novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia

Enterovirus 71 vaccine candidate strains exhibit good immunogenicity and cross-neutralization activity

Researchers identify key molecules that may help combat inflammatory diseases

An in-depth assessment into origin and spread of SARS-CoV-2 Delta variant in Brazil

Third COVID-19 mRNA vaccine booster dose indicated for myelofibrosis patients

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

Chronic COVID-19 and divergent variants of SARS-CoV-2

Review of COVID-19 clinical and viral characteristics, pathogenesis, and genetics

Withdrawal from psychostimulants alters functional architecture and patterns in the brain

$6 million CDC grant to support U-M researchers in reducing youth firearm violence

Limited evidence colchicine reduces COVID-19 related hospitalization

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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