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Bariatric surgery reduces brain pressure in patients with idiopathic intracranial hypertension

Weight loss surgery is more effective than dieting to reduce brain pressure that can cause blindness in patients with a neurological condition, finds a study led by the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust.

26 Apr 2021

Hypoxia radioactive marker will detect aggressiveness of tumors, eliminating the need for biopsy

Scientific advances in cancer research and new means of diagnosis and treatment have made it possible to cure many patients.

26 Apr 2021

Commonly-prescribed drug for IBD blunts COVID-19 vaccine response

People who take a commonly-prescribed drug for inflammatory bowel disease (IBD) should not assume they are protected after a first dose of COVID-19 vaccine, after a large-scale study found many had poor antibody responses.

26 Apr 2021

Researchers characterize India’s devastating second wave of COVID-19

The COVID-19 pandemic continues to take a heavy toll on human health worldwide. The second wave in India has caught everyone by surprise, showing up the total lack of foresight or precautions. With well over 0.2 million deaths in India, and infections raging out of control, a new study predicts 0.35 million daily cases at the peak of the second wave.

26 Apr 2021

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

However, with the waning of the immune response, it is not clear if these older people respond to the vaccine as well as younger individuals do. A recent study explored this question and found that though the antibody levels were somewhat lower in this group, they were still robust. This is a promising observation.

26 Apr 2021

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

A new study deals with the inhibitory activity of a membrane protein that has broad-spectrum activity against multiple viruses, showing that this is due to its effect on cytoplasmic lysine residue incorporation into replicating virions.

26 Apr 2021

Could pooled testing really improve COVID-19 transmission management and decrease costs?

Pooled testing for SARS-CoV-2 detection is instrumental for increasing test capacity while decreasing test cost. A team of researchers at Yale School of the Environment determined the barriers to implementing pooled testing in United States laboratories. The study showed that many laboratories use many instruments in their testing procedures, varying in the number of samples each can process.

26 Apr 2021

Previous SARS-CoV-2 infection associated with more adverse events following mRNA vaccination

The phase 3 trials of the Pfizer and Moderna COVID-19 vaccines did not include those with a known previous SARS-CoV-2 infection. Recent evidence indicates that mRNA vaccines may induce more adverse events in these individuals. In a recent study, 947 individuals, 265 of which have previously reported SARS-CoV-2 infection, were monitored post-vaccination for adverse events, finding that there could be a link between previous infection and greater incidence of these events.

26 Apr 2021

Cleavage site recognition by SARS-CoV-2 main protease as new antiviral drug target

Many research groups have and are investigating main protease inhibitors as antiviral drugs, and in a paper recently uploaded to the bioRxiv* preprint server, a team of researchers examine the crystal structure of the protein while bound to various viral substrate peptides (P1-4). In doing so, they reveal the way in which the bound peptide sequence can direct and modulate enzyme activity, providing new templates towards antiviral drug design.

26 Apr 2021

Researchers examine potential SARS-CoV-2 antivirals using a drug repurposing library

A new study deals with the screening of the Drug Repurposing Hub (DRH) library for identifying small compounds which are capable of inhibiting SARS-CoV-2 using both in vitro and in vivo experimental studies. These molecules could be used for designing a novel therapeutic system against SARS-CoV-2 infection.

26 Apr 2021

Fighting malaria in 2021: Where are we now and where are we going?

In support of World Malaria Day, News-Medical spoke to Dr. Laurence Slutsker, an internationally recognized expert in malaria, about fighting this disease in 2021.

26 Apr 2021

Using estrogen to target drug-resistant breast cancer in mice

Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it.

26 Apr 2021

Researchers harness the body's own ability to block pain

Fentanyl, oxycodone, morphine--these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.

26 Apr 2021

High dose of vitamin D does not have a beneficial effect on moderate or severe COVID-19 patients

Can a high dose of vitamin D administered on admission to hospital improve the condition of patients with moderate or severe COVID-19? The answer is no, according to a Brazilian study published in the Journal of the American Medical Association.

23 Apr 2021

Study sheds light on the ability of CBD to reduce pain

It's been hailed as a wonder drug and it's certainly creating wonder profits. By some estimates, the Cannabidiol (or CBD) market could be worth $20 billion dollars by 2024.

23 Apr 2021

Research could inform therapeutic approaches to ameliorate the effects of fetal immobility

Researchers from Trinity College Dublin have discovered that some skeletal defects associated with a lack of movement in the womb during early development may still be ameliorated after such periods of immobility if movement resumes.

23 Apr 2021

Researchers investigate how philosophical approaches can change the understanding of pain

Dr. Sabrina Coninx from Ruhr-Universität Bochum and Dr. Peter Stilwell from McGill University, Canada, have investigated how philosophical approaches can be used to think in new ways about pain and its management.

23 Apr 2021

Regulatory protein in skeletal muscle fiber may play a key role in the body's fight or flight response

Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful situations.

23 Apr 2021

People with a higher Omega-3 Index lived longer than others, study shows

A new research paper examining the relationship between the Omega-3 Index and risk for death from any and all causes has been published in Nature Communications.

23 Apr 2021

Heart brain interactions provide a new diagnostic avenue for patients with disorders of consciousness

A new study conducted jointly by the University of Liege (Belgium) and the Ecole normale superieure - PSL (France) shows that heart brain interactions, measured using electroencephalography (EEG), provide a novel diagnostic avenue for patients with disorders of consciousness.

23 Apr 2021

Medical Science News

Bariatric surgery reduces brain pressure in patients with idiopathic intracranial hypertension

Hypoxia radioactive marker will detect aggressiveness of tumors, eliminating the need for biopsy

Commonly-prescribed drug for IBD blunts COVID-19 vaccine response

Researchers characterize India’s devastating second wave of COVID-19

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

Could pooled testing really improve COVID-19 transmission management and decrease costs?

Previous SARS-CoV-2 infection associated with more adverse events following mRNA vaccination

Cleavage site recognition by SARS-CoV-2 main protease as new antiviral drug target

Researchers examine potential SARS-CoV-2 antivirals using a drug repurposing library

Fighting malaria in 2021: Where are we now and where are we going?

Using estrogen to target drug-resistant breast cancer in mice

Researchers harness the body's own ability to block pain

High dose of vitamin D does not have a beneficial effect on moderate or severe COVID-19 patients

Study sheds light on the ability of CBD to reduce pain

Research could inform therapeutic approaches to ameliorate the effects of fetal immobility

Researchers investigate how philosophical approaches can change the understanding of pain

Regulatory protein in skeletal muscle fiber may play a key role in the body's fight or flight response

People with a higher Omega-3 Index lived longer than others, study shows

Heart brain interactions provide a new diagnostic avenue for patients with disorders of consciousness

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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