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Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Researchers from the University of Southern California investigated mutations in the N-terminal and RBD domains of the spike protein.

20 Sep 2021

Medical staff with a history of allergy suffered adverse reactions to BNT162b2 COVID-19 vaccine

Scientists have addressed the gap in the research regarding the adverse reactions to the COVID-19 vaccine among individuals with allergies.

20 Sep 2021

First dose of COVID-19 mRNA vaccine (BNT162b2) reduced platelet polyP levels in young females

In a recent study, scientists have tested the hypothesis that indicates the role of polyP in the COVID-19 mRNA vaccine-induced immune responses.

20 Sep 2021

Characterizing the flexibility of SARS-CoV-2 variant of concern spike proteins

A novel protein modeling method assesses changes to the conformation of the SARS-CoV-2 spike protein that have been encountered by mutation.

19 Sep 2021

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Guinea recently experienced its second outbreak of the Ebola virus disease within the last decade.

19 Sep 2021

Development of a potential pan-variant aerosol to manage COVID-19

Researchers hypothesized that if APN01 could be directly introduced into the airways of an infected person, it could locally neutralize SARS-CoV-2.

19 Sep 2021

A variant analysis approach for SARS-CoV-2 in wastewater samples

A recent study proposes a simple and specific method for the enhanced detection of the SARS-CoV-2 VOCs in wastewater samples.

19 Sep 2021

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

In a recent study, Swiss researchers use improved techniques to understand the biological significance behind the Delta variant.

19 Sep 2021

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.

18 Sep 2021

R37 MERIT Award supports innovative ovarian cancer research

One of the most impactful advancements during the past decade in treating ovarian cancer is the use of PARP inhibitors (short for poly adenosine diphosphate-ribose polymerase). PARP inhibitors are a type of cancer drug that blocks the PARP enzyme from helping to repair DNA damage in cancer cells.

18 Sep 2021

Third dose of Pfizer-BioNTech vaccine increases neutralizing antibody levels against SARS-CoV-2

A third dose of the Pfizer-BioNTech vaccine significantly increased neutralizing antibody levels against SARS-CoV-2, the virus that causes COVID-19, according to new research published in the New England Journal of Medicine.

18 Sep 2021

Higher white matter extracellular free-water related to cognitive dysfunction in lupus patients

Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system attacks the body's own tissues, causing widespread inflammation and damage in the affected organs.

18 Sep 2021

Cross-species locomotion features shared by dopamine-deficient worms, mice, and humans

Scientists from the Graduate School of Information Science and Technology at Osaka University used animal location tracking along with artificial intelligence to automatically detect walking behaviors of movement disorders that are shared across species.

18 Sep 2021

Increased presence of certain bacteria in the gut may indicate colon cancer risk

A study published today in the journal Cell Host & Microbe reported that the increased presence of certain bacteria in a gut biome indicates a greater likelihood that colon polyps will become cancerous.

18 Sep 2021

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated.

18 Sep 2021

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

In contrast to intramuscular vaccines, only nasal vaccines are able to block the virus in the nose by inducing local immunity in the nasal mucosa, i.e. the portal of entry and multiplication of the virus.

18 Sep 2021

Two-hour glucose tolerance test helps identify patients at heightened risk of cognitive decline

Diabetes is a risk factor for cognitive decline. In a study of the University of Turku and Finnish Institute for Health and Welfare, the researchers observed that already a higher two-hour glucose level in the glucose tolerance test predicts worse performance in a test measuring episodic memory after ten years.

18 Sep 2021

What pushed Israel out of herd immunity?

Scientists have recently tried to explain the factors that could be responsible for the recent outbreaks of COVID-19 in Israel.

17 Sep 2021

Humoral and cellular response to COVID-19 vaccines in patients with IBD

A new study published in the preprint server medRxiv* aimed to evaluate the humoral and cellular response to COVID-19 vaccine in patients with IBD undergoing biologic or immunomodulatory therapy.

17 Sep 2021

Scientists identify new approach to overcome resistance to cancer immunotherapy

Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for Immunotherapy of Cancer.

17 Sep 2021

Medical Science News

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Medical staff with a history of allergy suffered adverse reactions to BNT162b2 COVID-19 vaccine

First dose of COVID-19 mRNA vaccine (BNT162b2) reduced platelet polyP levels in young females

Characterizing the flexibility of SARS-CoV-2 variant of concern spike proteins

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Development of a potential pan-variant aerosol to manage COVID-19

A variant analysis approach for SARS-CoV-2 in wastewater samples

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

R37 MERIT Award supports innovative ovarian cancer research

Third dose of Pfizer-BioNTech vaccine increases neutralizing antibody levels against SARS-CoV-2

Higher white matter extracellular free-water related to cognitive dysfunction in lupus patients

Cross-species locomotion features shared by dopamine-deficient worms, mice, and humans

Increased presence of certain bacteria in the gut may indicate colon cancer risk

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

A 100% French nasal vaccine against SARS-CoV-2 to move into the clinical phase in 2022

Two-hour glucose tolerance test helps identify patients at heightened risk of cognitive decline

What pushed Israel out of herd immunity?

Humoral and cellular response to COVID-19 vaccines in patients with IBD

Scientists identify new approach to overcome resistance to cancer immunotherapy

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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