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Could in vitro glycoengineering help produce better SARS-CoV-2 spike candidates for vaccine research?

A vexing problem in the development of vaccines has been the need to achieve the right glycosylation profile for the viral antigens. A new study, recently released as a preprint on the bioRxiv* server, shows how a sequential cell-free approach produced complex N-glycans from simpler types, in a one-pot reaction.

4 May 2021

Unique system detects small changes in DNA structures

Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they've been extremely difficult to detect -- until now.

4 May 2021

Developmental abnormalities are controlled by genetics of the fetus and placenta

Yale researchers have shown that developmental abnormalities, including those that lead to pregnancy loss and autism, are controlled by the genetics of the fetus and placenta -- and not the mother's intrauterine environment.

4 May 2021

Ravi Sheth receives 2020 Hertz thesis prize for transforming microbial research

Hertz Fellow Ravi Sheth says his lab in the Brooklyn Navy Yard is "like a Willy Wonka factory of microbes" geared toward improving the taste and safety of food and beverages.

4 May 2021

A new 3D model for myotonic dystrophy

Myotonic dystrophy is a hereditary degenerative neuromuscular disease that occurs mainly in adults, affecting about 50,000 people only in Spain.

4 May 2021

Researchers discover new way to improve the subcutaneous administration of mRNA

If not before, then certainly since the first messenger RNA (mRNA) vaccines to combat the SARS CoV2 virus were approved in Germany, mRNA has become a recognized term even outside scientific circles.

4 May 2021

New medical technology helps stop traumatic bleeding on the battlefield

A new medical technology stops traumatic bleeding without requiring wound compression for Soldiers on the battlefield. Hemorrhaging is a leading cause of preventable death for Soldiers in combat.

3 May 2021

IBEC researchers discover the neural mechanism of autonomous learning

Thanks to the so-called deep learning, a subset of artificial intelligence (AI) algorithms inspired by the brain, machines can match human performance in perception and language recognition and even outperform humans in certain tasks. But do these synthetic biologically inspired systems learn in the same way that we do?

3 May 2021

Simple application of UVC light could make common disinfectants safer to use

Over 400 common disinfectants currently in use could be made safer for people and the environment and could better fight the COVID-19 virus with the simple application of UVC light, a new study from the University of Waterloo shows.

3 May 2021

Study highlights the importance of improving real and perceived motor competence in children

he AIFPS (Physical Activity and Health Promotion) research group of the University of Valencia has carried out a study that has made it possible to develop longitudinal profiles based on real and perceived motor competence (MC), and the physical condition of boys and girls aged 4 to 9.

3 May 2021

NSAIDs could help mitigate the short-term impacts of air pollution on cognition

Exposure to air pollution, even over the course of just a few weeks, can impede mental performance, according to a new study led by researchers at Columbia University Mailman School of Public Health.

3 May 2021

Scientists investigate the role played by genes and environment in multiple substance use

Many drug addicts take not only one substance but rather several. Scientists at the Max Planck Institute of Experimental Medicine in Göttingen have investigated the role that genes and the environment play in the development of such multiple substance consumption or polytoxicomania.

3 May 2021

SARS-CoV-2 antibodies are detectable up to a year after infection, finds study

A team of scientists from the United States has recently investigated the robustness and durability of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in coronavirus disease 2019 (COVID-19) patients. Their findings reveal that COVID-19 patients exhibit a strong anti-SARS-CoV-2 antibody response for up to 1 year and that the robustness of antibody response depends on the patient’s age and disease severity.

3 May 2021