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New optic nerve stimulation protocol develops personalized visual signals to help the blind

Stimulation of the nervous system with neurotechnology has opened up new avenues for treating human disorders, such as prosthetic arms and legs that restore the sense of touch in amputees, prosthetic fingertips that provide detailed sensory feedback with varying touch resolution, and intraneural stimulation to help the blind by giving sensations of sight.

17 Jun 2021

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that the heart is unable to fill properly with blood.

17 Jun 2021

Using PET-CT scans to track the elimination of radiolabeled plastic particles in mice

Postdoctoral Researcher Outi Keinänen from the University of Helsinki developed a method to radiolabel plastic particles in order to observe their biodistribution on the basis of radioactivity with the help of positron emission tomography (PET).

17 Jun 2021

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they're needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue.

17 Jun 2021

Importance of understanding different factors that causes ST segment abnormalities

In a new publication from Cardiovascular Innovations and Applications; Sharen Lee, Gary Tse, Xin Wang, Adrian Baranchuk and Tong Liu from Laboratory of Cardiovascular Physiology, Hong Kong, China, Second Hospital of Tianjin Medical University, Tianjin, China and Queen's University, Kingston, Ontario, Canada consider ST-segment depression in leads I and aVL.

16 Jun 2021

Bruisable artificial skin opens up opportunities for detecting damage in prosthetic devices

When someone bumps their elbow against a wall, they not only feel pain but also might experience bruising. Robots and prosthetic limbs don't have these warning signs, which could lead to further injury.

16 Jun 2021

UMSOM researchers receive $5 million federal grant to improve use of genetic risk scores

Researchers at the University of Maryland School of Medicine (UMSOM) have received a $5 million federal grant to pool genomic information from existing and new datasets - predominantly in African and African American populations -- in order to calculate the risk of developing specific diseases.

16 Jun 2021

Early-stage lung cancer coopts macrophages to help tumors invade lung tissues

Immune cells that normally repair tissues in the body can be fooled by tumors when cancer starts forming in the lungs and instead help the tumor become invasive, according to a surprising discovery reported by Mount Sinai scientists in Nature in June.

16 Jun 2021

Novel altruistic stem cell defense mechanism may be targeted to develop new COVID-19 vaccines

The SARS-CoV-2 virus that causes COVID-19 may have the ability to reactivate dormant tuberculosis (TB). In a novel study scientists report in The American Journal of Pathology that infection with a specific coronavirus strain reactivated dormant Mycobacterium tuberculosis (MTB) in mice.

16 Jun 2021

Research identifies distinctive inflammatory signature in a genetic form of ALS

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative disease that strikes nearly 5,000 people in the U.S. every year. About 10% of ALS cases are inherited or familial, often caused by an error in the C9orf72 gene.

16 Jun 2021

Researchers find several persistent industrial chemicals in fetal organs

Researchers at Karolinska Institutet in Sweden found industrial chemicals in the organs of fetuses conceived decades after many countries had banned the substances.

16 Jun 2021

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

UCLA Health will receive a $4.8 million grant from The National Institutes of Health to develop methods that will improve genetic risk estimates - polygenic risk scores - for specific diseases in people from diverse populations and mixed ancestries.

16 Jun 2021

$1 million grant awarded to eliminate the need for drug refrigeration

COVID-19 vaccines have been tested, validated and administered to millions of people around the world. But in some countries, the vaccines have yet to arrive in great enough numbers.

16 Jun 2021

Over-the-counter fungicide holds potential to disrupt steroid hormone levels

The active ingredient in medicines commonly used to treat yeast infections has the potential to disrupt steroid hormone levels, according to a study from the National Food Institute, Technical University of Denmark.

16 Jun 2021

Scientists reveal the mechanism of liquid-liquid phase separation of SARS-CoV-2 nucleocapsid

A team of scientists from the United States has recently revealed how interactions between the SARS-CoV-2 nucleocapsid protein and the double-stranded RNA motifs impart distinct droplet properties that can support multiple viral functions. The study is currently available on the bioRxiv* preprint server.

16 Jun 2021

Gut microbiome impacts stroke severity and post-stroke functional impairment

New findings from Cleveland Clinic researchers show for the first time that the gut microbiome impacts stroke severity and functional impairment following stroke.

16 Jun 2021

Reducing coronavirus-related mortality through senolytics

A study recently published in the journal Science explores the concept of senescent cells (SnC) having a hyperinflammatory response and the use of a class of small molecules called senolytics to combat this.

16 Jun 2021

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

UNC School of Medicine scientists led a collaboration of researchers to demonstrate a potentially powerful new strategy for treating cystic fibrosis (CF) and potentially a wide range of other diseases.

16 Jun 2021

Could daily rapid testing replace mandatory quarantine to prevent imported SARS-CoV-2 infections?

A new study, released as a preprint on the medRxiv* server, examines the relative effectiveness of varying strategies, such as pre-flight testing, longer or shorter periods of quarantine, tests for release, or daily testing after the flight, using modeling tools. The results show that it is feasible to avoid quarantine by the use of lateral flow testing daily for five days, achieving higher reductions in the number of secondary cases caused by an infected traveler in the country of destination.

16 Jun 2021

COVID-e-Vax DNA vaccine candidate elicits robust immune responses in preclinical trials

A new study, released as a preprint on the bioRxiv* server, describes the late-stage clinical trial efficacy of a new vaccine candidate based on a deoxyribonucleic acid (DNA) plasmid platform expressing the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. Among different constructs of the vaccine plasmid, the RBD was found to produce the most potent and broad immune response.

16 Jun 2021

Medical Science News

New optic nerve stimulation protocol develops personalized visual signals to help the blind

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Using PET-CT scans to track the elimination of radiolabeled plastic particles in mice

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Importance of understanding different factors that causes ST segment abnormalities

Bruisable artificial skin opens up opportunities for detecting damage in prosthetic devices

UMSOM researchers receive $5 million federal grant to improve use of genetic risk scores

Early-stage lung cancer coopts macrophages to help tumors invade lung tissues

Novel altruistic stem cell defense mechanism may be targeted to develop new COVID-19 vaccines

Research identifies distinctive inflammatory signature in a genetic form of ALS

Researchers find several persistent industrial chemicals in fetal organs

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

$1 million grant awarded to eliminate the need for drug refrigeration

Over-the-counter fungicide holds potential to disrupt steroid hormone levels

Scientists reveal the mechanism of liquid-liquid phase separation of SARS-CoV-2 nucleocapsid

Gut microbiome impacts stroke severity and post-stroke functional impairment

Reducing coronavirus-related mortality through senolytics

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

Could daily rapid testing replace mandatory quarantine to prevent imported SARS-CoV-2 infections?

COVID-e-Vax DNA vaccine candidate elicits robust immune responses in preclinical trials

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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