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Study reveals key role of fat cells in cognitive decline and neurodegeneration

Findings published this week reveal new insights into the role of fat cells in cognitive decline and neurodegeneration, according to a study that involves the oxidant amplification loop led by Marshall University scientists.

22 Oct 2021

Researchers identify mechanism behind insufficient treatment efficacy of psoriasis drugs

Interleukin-12 - a messenger molecule of immune cells - was long considered to trigger the development of psoriasis.

22 Oct 2021

Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Researchers tested analogs of disulfiram on SARS-CoV-2 Mpro and PLpro to find more efficient and effective inhibitors that take advantage of disulfiram’s mechanism of binding to the cysteine residue.

22 Oct 2021

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

A team of researchers measured the infectivity of SARS-CoV-2 variants C.1.2, Mu, and Delta+501S spike proteins and determined the susceptibility to neutralizing antibodies.

22 Oct 2021

SARS-CoV-2 anti-nucleocapsid antibodies reduce risk of reinfection for at least eight months

A new study concludes that at least with predominantly wild-type variants, the risk of reinfection with the virus among unvaccinated people is reduced by 80% or more.

22 Oct 2021

Study shows immune profile heterogeneity amongst healthy adults

Researchers opted to use single-cell RNA-seq to observe single cells in detail as they encounter a specific antigen.

22 Oct 2021

Using saliva to predict COVID-19 severity in children

News-Medical speaks to Dr. Usha Sethuraman about her research into COVID-19 and how saliva could be used to help predict COVID-19 severity in children.

22 Oct 2021

Health and climate change in Australia

The 2021 MJA–Lancet Countdown report represents a collaborative effort between University College London, and seven Australian institutions, mediated by The Lancet in partnership with The Medical Journal of Australia.

22 Oct 2021

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Scientists studied the efficacy of an intranasal booster composed of beta variant-spike protein S1 with IL-15 and TLR agonists in macaques that were previously immunized.

22 Oct 2021

Replication of SARS-CoV-2 variants in different cell and organ models

In this study, the replication of B.1.1.7 viruses was analyzed in different cell and organ models and dwarf hamsters.

22 Oct 2021

Development of a safe and effective COVID-19 nanoparticle vaccine

Researchers from ReVacc scientific have attempted to demonstrate the effectiveness of a new vaccine, REVC-128, two weeks post-administration.

22 Oct 2021

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Researchers from Stanford University have been attempting to create a hydrogel-based vaccine delivery system that could improve the immune response's strength and duration.

22 Oct 2021

Study maps neurons essential for social behavior and healthy relationships within groups

Meaningful social interactions are critical to an individual's well-being, and such interactions rely on people's behaviors towards one another.

22 Oct 2021

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

Boosting nonhuman primates with the Moderna vaccine (mRNA-1273) six months after their primary vaccine series increased neutralizing activity against viral variants of concern, a new study shows.

22 Oct 2021

Experts address the limitations of studying individual brains in cognitive neuroscience

In a new paper, scientists suggest that efforts to understand human cognition should expand beyond the study of individual brains. They call on neuroscientists to incorporate evidence from social science disciplines to better understand how people think.

22 Oct 2021

First investigational xenotransplantation marks a major step towards adequate organ supply

The first investigational transplant of a genetically engineered, nonhuman kidney to a human body was recently completed at NYU Langone Health—marking a major step forward in potentially utilizing an alternative supply of organs for people facing life-threatening disease.

21 Oct 2021

Research opens new avenues for topical treatment of skin fibrosis

Collagen, the main component of the skin's extracellular matrix, can cause a pathological condition if it is in excess.

21 Oct 2021

Duke awarded NIAID funding to develop the next generation of pan-coronavirus vaccines

The National Institute of Allergy and Infectious Diseases has awarded $17.5 million over three years to the Duke Human Vaccine Institute to develop a vaccine that protects against multiple types of coronaviruses and viral variants.

21 Oct 2021

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Scientists at St. Jude Children's Research Hospital have shown that cell-free DNA from cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children treated for the brain tumor medulloblastoma.

21 Oct 2021

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

Medical Science News

Study reveals key role of fat cells in cognitive decline and neurodegeneration

Researchers identify mechanism behind insufficient treatment efficacy of psoriasis drugs

Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

SARS-CoV-2 anti-nucleocapsid antibodies reduce risk of reinfection for at least eight months

Study shows immune profile heterogeneity amongst healthy adults

Using saliva to predict COVID-19 severity in children

Health and climate change in Australia

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Replication of SARS-CoV-2 variants in different cell and organ models

Development of a safe and effective COVID-19 nanoparticle vaccine

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Study maps neurons essential for social behavior and healthy relationships within groups

Boosting nonhuman primates with Moderna vaccine increases neutralizing antibody responses

Experts address the limitations of studying individual brains in cognitive neuroscience

First investigational xenotransplantation marks a major step towards adequate organ supply

Research opens new avenues for topical treatment of skin fibrosis

Duke awarded NIAID funding to develop the next generation of pan-coronavirus vaccines

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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