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An intranasal COVID-19 vaccine elicits long-lasting immunity against SARS-CoV-2 variants in vivo

A team of scientists from the Washington University School of Medicine and the University of Texas Medical Branch, USA, has recently evaluated the durability and robustness of an adenovirus-vectored, spike-based intranasal COVID-19 vaccine in mice.

11 May 2021

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Researchers have designed a new class of TMPRSS2 inhibitors that have shown broad antiviral activity against coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 May 2021

Experimental gene therapy successfully treats children born without an immune system

An experimental form of gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with a rare and deadly inherited disorder that leaves them without an immune system.

11 May 2021

Case study describes consequences of undetected SARS-CoV-2 infection during mRNA vaccination

Now, a new report describes a case of a coincidental mRNA vaccination and SARS-CoV-2 infection in a 31-year-old doctor, addressing the theoretical considerations for potential risks and further required actions in case more cases appear in the future.

11 May 2021

Machine learning approach helps study human hypothalamus at the single-cell level

Human brain organoids are remarkable platforms for modeling features of human brain development and diseases.

11 May 2021

Single-cell map offers a new immunotherapy target for lung cancer treatment

Researchers at The University of Texas MD Anderson Cancer Center have developed a first-of-its-kind spatial atlas of early-stage lung cancer and surrounding normal lung tissue at single-cell resolution, providing a valuable resource for studying tumor development and identifying new therapeutic targets.

11 May 2021

Researchers explore effects of reduced gravity on mouse skeletal muscles

Most of us have imagined how free it would feel to float around, like an astronaut, in conditions of reduced gravity. But have you ever considered what the effects of reduced gravity might have on muscles?

11 May 2021

New implantable system can manipulate brain signals and suppress pathological coupling

As researchers learn more about the brain, it has become clear that responsive neurostimulation is becoming increasingly effective at probing neural circuit function and treating neuropsychiatric disorders, such as epilepsy and Parkinson's disease.

10 May 2021

3D printing technique extends the possibilities of lateral flow tests

Researchers at KU Leuven (Belgium) have developed a 3D printing technique that extends the possibilities of lateral flow testing.

10 May 2021

New spray protocol improves delivery of nasal antiseptic to reduce COVID-19 infection

A trip to visit family in Kolkata, India, put South Dakota State University assistant professor Saikat Basu in the middle of that country's second wave of COVID-19 infections.

10 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

Previously overlooked hormone plays critical role in the development of endometriosis

Endometriosis, a disease found in up to 10 per cent of women, has been enigmatic since it was first described. A new theory developed by researchers at Simon Fraser University suggests a previously overlooked hormone -- testosterone -- has a critical role in its development.

10 May 2021

CDK inhibitors may boost the effectiveness of immune therapy in metastatic breast cancer

A class of drugs that inhibits breast cancer progression when used with hormonal therapy might also boost the effectiveness of immune therapy in cases of recurrent, metastatic breast cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

10 May 2021

Study discovers harmful inflammatory protein in patients with symptomatic tuberculosis

A pioneering study by UCL scientists has discovered the presence of a harmful inflammatory protein in patients with symptomatic tuberculosis (TB).

10 May 2021

Blocking fat-busting enzyme with a drug compromises cardiac repair during acute heart failure

Blocking the fat-busting enzyme lipoxygenase with a synthetic inhibitor throws the immune system's innate inflammatory response out of whack, compromising cardiac repair during acute heart failure, USF Health researchers found.

10 May 2021

New vaccine shows potential to protect from a variety of coronavirus infections

A potential new vaccine developed by members of the Duke Human Vaccine Institute has proven effective in protecting monkeys and mice from a variety of coronavirus infections -- including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandemic.

10 May 2021

New filling method to treat cerebral aneurysms

Cerebral aneurysms are malformations caused by abnormalities on the walls of blood vessels in the brain. When these blood vessels rupture, about 30% of the sufferers die on the spot, giving these the rightful label of 'ticking bombs in the head'.

10 May 2021

Research suggests Pfizer-BioNTech COVID-19 vaccine reprograms innate immune responses

Researchers in The Netherlands have warned that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines.

10 May 2021

Novel approach to immunotherapy design could pave the way for new brain cancer treatments

A novel approach to immunotherapy design could pave the way for new treatments for people with an aggressive form of brain cancer called glioblastoma.

10 May 2021

Scientists produce a universal flu vaccine using nanoparticles to induce long-lasting immunity

Researchers at the National Institute of Allergy and Infectious Diseases (NIAID)’s Vaccine Research Center (VRC) and the University of Washington School of Medicine’s Institute for Protein Design (IPD) developed a universal flu vaccine candidate using small particles (nanoparticles), which can induce a long-lasting immune response.

10 May 2021

Medical Science News

An intranasal COVID-19 vaccine elicits long-lasting immunity against SARS-CoV-2 variants in vivo

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Experimental gene therapy successfully treats children born without an immune system

Case study describes consequences of undetected SARS-CoV-2 infection during mRNA vaccination

Machine learning approach helps study human hypothalamus at the single-cell level

Single-cell map offers a new immunotherapy target for lung cancer treatment

Researchers explore effects of reduced gravity on mouse skeletal muscles

New implantable system can manipulate brain signals and suppress pathological coupling

3D printing technique extends the possibilities of lateral flow tests

New spray protocol improves delivery of nasal antiseptic to reduce COVID-19 infection

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Previously overlooked hormone plays critical role in the development of endometriosis

CDK inhibitors may boost the effectiveness of immune therapy in metastatic breast cancer

Study discovers harmful inflammatory protein in patients with symptomatic tuberculosis

Blocking fat-busting enzyme with a drug compromises cardiac repair during acute heart failure

New vaccine shows potential to protect from a variety of coronavirus infections

New filling method to treat cerebral aneurysms

Research suggests Pfizer-BioNTech COVID-19 vaccine reprograms innate immune responses

Novel approach to immunotherapy design could pave the way for new brain cancer treatments

Scientists produce a universal flu vaccine using nanoparticles to induce long-lasting immunity

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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