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Texas Biomed awarded $1 million to evaluate MAb therapeutics for COVID-19

Texas Biomedical Research Institute in San Antonio, Texas, was awarded $1 million from the Bill & Melinda Gates Foundation to test the efficacy of human monoclonal antibodies (MAbs) for the treatment of SARS-CoV-2 infection.

19 Nov 2020

New druggable target for heart failure in neonates and infants identified

Researchers have identified a new druggable target for heart failure in neonates and infants, a condition for which there has been no specific treatment.

19 Nov 2020

Seroprevalence meta-analysis predicts 643 million already infected by SARS-CoV-2 globally

A recent systematic review and meta-analysis conducted by a team of international scientists reveal low seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the general population.

19 Nov 2020

Researchers uncover potential new target to fight inflammatory diseases

An international team of researchers have uncovered a drug-like compound that blocks a crucial inflammatory pathway, potentially paving the way for a new treatment for a host of diseases - including COVID-19.

19 Nov 2020

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

In a recent study, a team of researchers at Northwestern University, USA, had found that nearly 20 percent seroprevalence in the United States metropolitan site, Chicago, over the summer, during a period when lockdown restrictions were eased. They found that three-quarters of seropositive individuals retained detectable antibodies for at least 120 days or four months.

19 Nov 2020

Study shows link between COPD and the gut microbiome

Research led by the Centenary Institute, the University of Technology Sydney and the University of Queensland has shown for the first time a link between chronic obstructive pulmonary disease (COPD), an often fatal lung condition, and the gut microbiome.

19 Nov 2020

Carrageenan-based composite nasal spray may help prevent SARS-CoV-2 infection

A team of researchers at the University of Birmingham in the United Kingdom formulated a spray that contains polysaccharides known for their mucoadhesive antiviral properties for prophylaxis against SARS-CoV-2 infection.

19 Nov 2020

The impact of the COVID-19 pandemic on those with OCDs

Researchers from the University Medical Centre Hamburg-Eppendorf and University Hospital, Munich in Germany, have reported their findings on the course of obsessive-compulsive disorders (OCDs) during the coronavirus disease 2019 (COVID-19) pandemic.

19 Nov 2020

SARS-CoV-2 immunity can last over six months, study finds

US-based scientists have released a study on preprint server bioRxiv*, titled “Immunological memory to SARS-CoV-2 assessed for greater than six months after infection,” contributing to the enormous research effort currently underway in this area.

19 Nov 2020

Researchers find new link between incretin hormones and arteriosclerosis

Diabetes is currently treated using incretin hormones to reduce the risk of cardiovascular disease and other medical issues that the illness can trigger.

19 Nov 2020

Researchers use bioinformatics methods to identify key genes in dilated cardiomyopathy

In a new publication from Cardiovascular Innovations and Applications, Yukuan Chen, Xiaohui Wu, Danchun Hu and Wei Wang, from the Shantou University Medical College, Shantou, China and Second Affiliated Hospital of Shantou University Medical College, Shantou, China consider the importance of mitochondrial-related genes in dilated cardiomyopathy.

19 Nov 2020

Genetic variations of SARS-CoV-2 transmission in cats

Using cats as an animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, researchers have determined the virus has a narrow transmission bottleneck.

19 Nov 2020

Immune mechanism responsible for adverse inflammatory reactions after stem cell transplant identified

In the treatment of leukemia, stem cell transplantation subsequent to chemotherapy and radiation can often engender severe adverse inflammatory reactions - especially in the skin or in the gut, since these so-called barrier organs are more frequently affected.

19 Nov 2020

Delirium in older patients with COVID-19

Delirium is common in older patients admitted to US emergency departments with COVID-19 infection, according to the findings of a new study.

19 Nov 2020

Researchers develop wireless chip that can be surgically implanted to read neural signals

Researchers have developed a chip that is powered wirelessly and can be surgically implanted to read neural signals and stimulate the brain with both light and electrical current. The technology has been demonstrated successfully in rats and is designed for use as a research tool.

19 Nov 2020

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Organ and stem cell transplants are proven and frequently used methods in everyday modern clinical practice. However, even when performed regularly in specialized centers, some patients still experience a number of serious complications afterward.

19 Nov 2020

Research on genetic heart disease uncovers new mechanism for heart failure

Research on genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy.

19 Nov 2020