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Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

Cancer is the world's second deadliest disease which contributes towards the fatality of over 10 million people per year.

3 Apr 2021

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.

3 Apr 2021

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the cancer cells.

3 Apr 2021

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer's disease in a new study by investigators at the University of Chicago.

3 Apr 2021

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma.

3 Apr 2021

Research provides insights on why redheads exhibit altered sensitivity to pain

New research led by investigators at Massachusetts General Hospital provides insights on why people with red hair exhibit altered sensitivity to certain kinds of pain. The findings are published in Science Advances.

2 Apr 2021

Higher B.1.1.7 transmission in households than other SARS-CoV-2 variants

Contact tracing data from a new preprint study on the medRxiv* preprint server provides further evidence that the B.1.1.7 variant — first reported in the United Kingdom — has a high transmission rate. The research, led by Birgitte Freiseleben de Blasio from the Norwegian Institute of Public Health and the University of Oslo in Norway, estimates B.1.1.7 has a 60% greater transmission within households than other severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.

2 Apr 2021

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

There have been concerns that several SARS-CoV-2 variants have mutations that allow them to evade the immune system. A new study published in the Open Forum Infectious Diseases suggests otherwise. Led by Aaron AR Tobian of Johns Hopkins University School of Medicine, results showed that except for one from the B.1.351 variant, CD8+ T cells showed a broad response to all SARS-CoV-2 variants.

2 Apr 2021

Long-COVID-19 is a significant risk in recovered patients post-hospitalization

A new study, which appeared in the British Medical Journal, reports on a retrospective study to examine the incidence and risk factors for ‘long COVID-19’, the term used to describe the long-term effects of COVID-19 on affected individuals.

2 Apr 2021

Proper choice of control group nullifies most observed genetic markers for severe COVID-19, study suggests

A new study deals with the genetic contribution to severe disease following infection with this virus, showing that the association of severity with specific human genes described in an earlier study is not obvious.

2 Apr 2021

Researchers offer large-scale screening of potential broad-spectrum SARS-CoV-2 antivirals

A new study describes the identification of new compounds from a library, with inhibitory activity against several coronaviruses. This study shows the utility of this method, besides identifying compounds that not only inhibit viral shedding in SARS-CoV-2 cultures, but have an immunomodulatory effect that may be useful in mitigating the damaging cytokine storm typical of severe or critical COVID-19.

2 Apr 2021

Comparative study of SARS, MERS, BAT‐SARS, and SARS-CoV-2

Even though a comparative study on the genomic sequences of SARS-CoV, MERS-CoV, and SARS-CoV-2 is available, there is a gap in the research in regards to the comparison between four types of coronaviruses, namely, SARS-CoV, MERS-CoV, BAT-CoV, and SARS-CoV-2. A new study, which deals with the genomic comparison between the sequence of the above-stated four types of coronaviruses, has been published in the Journal of Medical Virology.

2 Apr 2021

Internal states can also have an impact on learning, shows study

We've all heard the adage, "If at first you don't succeed, try, try again," but new research from Carnegie Mellon University and the University of Pittsburgh finds that it isn't all about repetition. Rather, internal states like engagement can also have an impact on learning.

2 Apr 2021

Suppressing facial expressions may be useful in certain contexts, shows study

How do our facial expressions in response to seeing others in pain influence how we see and feel their pain? There are many situations where it may be helpful to suppress our emotional responses to the pain of others.

2 Apr 2021

Mimes help humans to “see” objects that are invisible

When we watch a mime seemingly pull rope, climb steps or try to escape that infernal box, we don't struggle to recognize the implied objects -- our minds automatically "see" them, a new study concludes.

2 Apr 2021

Mice experiencing hallucination-like events provide clues to understand psychosis

The humble lab mouse has provided invaluable clues to understanding diseases ranging from cancer to diabetes to COVID-19. But when it comes to psychiatric conditions, the lab mouse has been sidelined, its rodent mind considered too different from that of humans to provide much insight into mental illness.

1 Apr 2021

Restoring dysfunctional lymphatic networks to allow the body to fight disease

The human body is an incredibly designed machine, and mechanical processes such as those in the lymphatic system play major roles in maintaining healthy tissue and organs.

1 Apr 2021

Novel method uses device cameras to measure physiological signals from real-time video of the face

Telehealth has become a critical way for doctors to still provide health care while minimizing in-person contact during COVID-19. But with phone or Zoom appointments, it's harder for doctors to get important vital signs from a patient, such as their pulse or respiration rate, in real time.

1 Apr 2021

HCAs are a promising risk indicator of type 2 diabetes

A series of studies led by researchers from Hong Kong Baptist University have revealed that hyocholic acid and its derivatives (collectively known as HCAs), a component of bile acids that facilitate fat digestion, are a promising risk indicator of type 2 diabetes.

1 Apr 2021

Signal detection theory can be used to better understand cognitive fatigue

A team of New Jersey researchers has shown that changes in perceptual certainty and response bias, two central metrics of signal detection theory (SDT), correlate with changes in cognitive fatigue.

1 Apr 2021

Medical Science News

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response

Research provides insights on why redheads exhibit altered sensitivity to pain

Higher B.1.1.7 transmission in households than other SARS-CoV-2 variants

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

Long-COVID-19 is a significant risk in recovered patients post-hospitalization

Proper choice of control group nullifies most observed genetic markers for severe COVID-19, study suggests

Researchers offer large-scale screening of potential broad-spectrum SARS-CoV-2 antivirals

Comparative study of SARS, MERS, BAT‐SARS, and SARS-CoV-2

Internal states can also have an impact on learning, shows study

Suppressing facial expressions may be useful in certain contexts, shows study

Mimes help humans to “see” objects that are invisible

Mice experiencing hallucination-like events provide clues to understand psychosis

Restoring dysfunctional lymphatic networks to allow the body to fight disease

Novel method uses device cameras to measure physiological signals from real-time video of the face

HCAs are a promising risk indicator of type 2 diabetes

Signal detection theory can be used to better understand cognitive fatigue

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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