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Anti-diarrhea drug triggers cell death in glioblastoma cells

In cell culture, loperamide, a drug commonly used against diarrhea, proves effective against glioblastoma cells. A research team at Goethe University has now unraveled the drug’s mechanisms of action of cell death induction and – in doing so – has shown how this compound could help attack brain tumors that otherwise are difficult to treat.

22 Dec 2020

COVID-19 patients retain immunity against the virus for at least 8 months

Australian researchers have revealed - for the first time - that people who have been infected with the COVID-19 virus have immune memory to protect against reinfection for at least eight months.

22 Dec 2020

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Researchers have measured the antibody levels and types in hospitalized coronavirus disease 2019 (COVID-19) patients with different disease severity. Their results suggest gut immune pathways could play a role in reducing virus-based inflammation and recovery.

22 Dec 2020

Trinity team uncovers mutations linked with early onset dementia

Scientists at Trinity College Dublin today announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease.

22 Dec 2020

Scientists isolate anti-COVID-19 nanobodies produced by a llama

National Institutes of Health researchers have isolated a set of promising, tiny antibodies, or "nanobodies," against SARS-CoV-2 that were produced by a llama named Cormac.

22 Dec 2020

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

A team of researchers from the Johns Hopkins University, USA; Imperial College London, UK; and Foundation for Innovative New Diagnostics, Switzerland, recently compared the effectiveness of Ag-RDT, NAAT, and clinical judgment alone in the diagnosis of COVID-19 in symptomatic patients.

22 Dec 2020

Large proportion of UK population hesitant over COVID-19 vaccine

Researcher Dr. Alex de Figueiredo from the London School of Hygiene and Tropical Medicine has conducted a study showing that a significant proportion of people in the UK will probably be reluctant to receive a vaccine to protect against coronavirus disease 2019 (COVID-19).

22 Dec 2020

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

Researchers from Public Health England are conducting a large-scale prospective longitudinal study to determine whether healthcare workers who have previously developed coronavirus disease 2019 (COVID-19) are immune to reinfection with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Dec 2020

Nanoplastics affect composition and diversity of human intestinal microbiome

We live in a world invaded by plastic. Its role as a chemically stable, versatile and multi-purpose fostered its massive use, which has finally translated into our current situation of planetary pollution.

22 Dec 2020

Study shows how specific Salmonella bacteria evolved to cause bloodstream infection

University of Liverpool scientists have exploited the combined power of genomics and epidemiology to understand how a type of Salmonella bacteria evolved to kill hundreds of thousands of immunocompromised people in Africa.

22 Dec 2020

Study reveals how the immune system detects signs of disease, activates a protective response

Researchers at the Francis Crick Institute have uncovered an important process in how our immune system detects signs of disease and activates a protective response. This understanding could improve efforts to find new and effective immunotherapy treatments for diseases like cancer.

22 Dec 2020

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Immune inflammatory mediators are critical in pathology, transplantation, and regenerative medicine, scientists report in The American Journal of Pathology

22 Dec 2020

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

An infant's odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate technique to examine the IRAK4 gene responsible for innate immunity.

22 Dec 2020

Study sheds new light on immune system interactions with cancer

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

21 Dec 2020

Study depicts previously unknown molecular mechanism underlying healthy brain development

A research team led by Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC, has identified the type of brain cell that produces collagen 19, a protein that is crucial for the formation of inhibitory circuits in the brain.

21 Dec 2020

High altitude experts explain pneumolysis caused by COVID-19

The current COVID-19 pandemic has caused over 1 million deaths which can be attributed to its severe progressive pulmonary compromise.

21 Dec 2020

Reston virus causes severe respiratory disease in piglets

Reston ebolavirus (RESTV) should be considered a livestock pathogen with potential to affect other mammals, including people, according to National Institutes of Health scientists.

21 Dec 2020

Nocturnal respiratory rate of heart patients can help predict the success of ICD treatment

onditions causing arrhythmia are among the most common cardiac conditions. A study headed by Prof. Georg Schmidt of the Technical University of Munich has demonstrated for the first time that the nocturnal respiratory rate can help with an important prediction: It is an indicator of whether a defibrillator will help to extend the life of patients with arrhythmia.

21 Dec 2020

Researchers explore why seizures happen in a subset of MS patients

A research team at the University of California, Riverside School of Medicine has identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures happen in a subset of multiple sclerosis, or MS, patients.

21 Dec 2020

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers.

21 Dec 2020

Medical Science News

Anti-diarrhea drug triggers cell death in glioblastoma cells

COVID-19 patients retain immunity against the virus for at least 8 months

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Trinity team uncovers mutations linked with early onset dementia

Scientists isolate anti-COVID-19 nanobodies produced by a llama

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

Large proportion of UK population hesitant over COVID-19 vaccine

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

Nanoplastics affect composition and diversity of human intestinal microbiome

Study shows how specific Salmonella bacteria evolved to cause bloodstream infection

Study reveals how the immune system detects signs of disease, activates a protective response

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

Study sheds new light on immune system interactions with cancer

Study depicts previously unknown molecular mechanism underlying healthy brain development

High altitude experts explain pneumolysis caused by COVID-19

Reston virus causes severe respiratory disease in piglets

Nocturnal respiratory rate of heart patients can help predict the success of ICD treatment

Researchers explore why seizures happen in a subset of MS patients

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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