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Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

In a methodologically trailblazing paper published in the journal Nature Genetics, a team of Belgian scientists uncovered an assembly of coronavirus host factors that may be exploited to develop drugs against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also potentially forthcoming zoonotic coronaviruses.

14 Mar 2021

Executive control differences in autism may be the result of a unique approach

A new study by UC Davis MIND Institute researchers suggests that executive control differences in autism spectrum disorder (ASD) may be the result of a unique approach, rather than an impairment.

13 Mar 2021

Immuno-PET detects changes in different cancer receptors in response to targeted therapies

Immuno-positron emission tomography (PET) imaging can provide early insight into a tumor's response to targeted therapy, allowing physicians to select the most effective treatment for patients who have cancer.

13 Mar 2021

Cats with chronic kidney disease may help inform treatment for humans in future

The Wake Forest Institute for Regenerative Medicine is investigating how cats with chronic kidney disease could someday help inform treatment for humans.

13 Mar 2021

Study finds visual correlation between severity of COVID-19 in the lungs and brain

Since the pandemic hit, researchers have been uncovering ways COVID-19 impacts other parts of the body, besides the lungs.

13 Mar 2021

New vaccination method aims at comprehensive protection against all known influenza mutations

One shot, protected forever: This would be a dream come true regarding influenza vaccinations. So far, vaccination against influenza did not provide a lasting protection.

13 Mar 2021

Researchers discover new mechanism that contributes to airway hyperresponsiveness in asthma

In asthma, the airways become hyperresponsive. Researchers from Uppsala University have found a new mechanism that contributes to, and explains, airway hyperresponsiveness.

13 Mar 2021

Overexpression of signaling protein in heart associated with poor survival after heart attack

About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate - some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease, for which new therapies are desperately needed.

13 Mar 2021

Researchers explore brain network differences between autistic and neurotypical control males and females

Around three times as many males are diagnosed with autism than females. This suggests that biological sex factors may play a role in the development and presentation of autism.

13 Mar 2021

Cancer cells may dodge chemotherapy by going into 'active hibernation'

Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of "active hibernation" that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study by scientists at Weill Cornell Medicine.

13 Mar 2021

Sound sleep plays a crucial role in healing traumatic brain injuries

Sound sleep plays a critical role in healing traumatic brain injury, a new study of military veterans suggests.

13 Mar 2021

Could horse-derived antibodies promote immunity against SARS-CoV-2 infection?

Researchers based in India have demonstrated that horses inoculated with an inactivated dosage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are able to produce large amounts of strong antibodies that can neutralize multiple variants

12 Mar 2021

Single-dose vaccines may provide sufficient immunization for individuals previously infected with SARS-CoV-2

A group of researchers based at the Papa Giovanni XXIII hospital in Italy have submitted evidence to suggest that individuals previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may adequately benefit from a single dose of mRNA vaccine, rather than requiring the current two-vaccine regimen.

12 Mar 2021

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

In a study published in the journal Drugs, a researcher tackled the approval of Pfizer-BioNTech’s COVID-19 vaccine, which has now been used in many countries.

12 Mar 2021

New examination method identifies high-risk plaques likely to cause adverse cardiac events

Researchers at Lund University in Sweden can now show that a new examination method identifies high-risk plaques in the blood vessels surrounding the heart, that cannot be seen solely with traditional angiograms.

12 Mar 2021

How common are post-acute sequelae of SARS-CoV-2 infection?

The COVID-19 pandemic has taken a heavy toll on human lives, with over two million casualties so far. Equally devastating has been its economic toll. Now, a new study describes the features and frequency of long-haul symptoms in COVID-19.

12 Mar 2021

Natural virus-induced immunity protective against UK and South African SARS-CoV-2 variants in hamster study

As new variants of SARS-CoV-2 continue to emerge, fueling the continued spread of the COVID-19 pandemic, a new study offers encouragement.

12 Mar 2021

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

A new preprint discusses the pathogenesis of this critical COVID-19 with reference to autoimmune phenomena involving the key antiviral type I interferon pathway.

12 Mar 2021

Antibodies to SARS-CoV-2 spike protein and RBD detected in saliva of mRNA-vaccine recipients

A team of researchers from the US and the Netherlands recently reported that antibodies to the spike protein and the RBD are detected in saliva samples from healthcare workers vaccinated with mRNA vaccines.

12 Mar 2021

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Researchers have found that SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment. Therefore, strategies such as focusing on limiting the production of IFN, rather than its function, could restrict the mechanism of SARS-CoV-2 that increases its viral load with delayed or absent symptoms.

12 Mar 2021

Medical Science News

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

Executive control differences in autism may be the result of a unique approach

Immuno-PET detects changes in different cancer receptors in response to targeted therapies

Cats with chronic kidney disease may help inform treatment for humans in future

Study finds visual correlation between severity of COVID-19 in the lungs and brain

New vaccination method aims at comprehensive protection against all known influenza mutations

Researchers discover new mechanism that contributes to airway hyperresponsiveness in asthma

Overexpression of signaling protein in heart associated with poor survival after heart attack

Researchers explore brain network differences between autistic and neurotypical control males and females

Cancer cells may dodge chemotherapy by going into 'active hibernation'

Sound sleep plays a crucial role in healing traumatic brain injuries

Could horse-derived antibodies promote immunity against SARS-CoV-2 infection?

Single-dose vaccines may provide sufficient immunization for individuals previously infected with SARS-CoV-2

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

New examination method identifies high-risk plaques likely to cause adverse cardiac events

How common are post-acute sequelae of SARS-CoV-2 infection?

Natural virus-induced immunity protective against UK and South African SARS-CoV-2 variants in hamster study

Impact of type I interferon (IFN) autoantibodies in critical COVID-19

Antibodies to SARS-CoV-2 spike protein and RBD detected in saliva of mRNA-vaccine recipients

SARS-CoV-2 is extremely sensitive to type I IFN pre-treatment, study finds

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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