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Sugar-binding protein could promote inflammation and worsen sepsis

A sugar-binding protein could fuel terrible inflammation and worsen sepsis, a disease that kills more than 270,000 people every year in the US alone, reports a team of researchers led by UConn Health in the 4 January issue of Nature Immunology.

4 Jan 2021

Epigenetic modulators have a rapid antidepressant-like effect, study shows

Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants.

4 Jan 2021

Inflammation marker linked to increased fatigue in prostate cancer patients treated with ADT

Prostate cancer is one of the most common cancers among men in the U.S. For many patients, hormone therapy is a treatment option.

4 Jan 2021

Six clearly distinguishable subtypes of prediabetes identified

All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases.

4 Jan 2021

People with detectable brown fat less likely to suffer cardiac and metabolic conditions

Brown fat is that magical tissue that you would want more of. Unlike white fat, which stores calories, brown fat burns energy and scientists hope it may hold the key to new obesity treatments.

4 Jan 2021

Smoking traditional cigarettes along with e-cigarettes causes harmful health effects

Smoking traditional cigarettes in addition to using e-cigarettes results in harmful health effects similar to smoking cigarettes exclusively, according to new research published today in the American Heart Association's flagship journal Circulation.

4 Jan 2021

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues.

4 Jan 2021

Scientists design experimental gut-brain system in a lab dish

Research into what is known as the gut-brain axis continues to reveal how the brain and gut influence each other's health and well-being. Now researchers are endeavoring to learn more about gut-brain discourse using a model system built in a lab dish.

4 Jan 2021

Anesthesia and sleep have surprisingly similar effects on brain activity, finds study

What happens in the brain when our conscious awareness fades during general anesthesia and normal sleep? Finnish scientists studied this question with novel experimental designs and functional brain imaging.

29 Dec 2020

Brain scans predict posttraumatic stress disorder following mild TBI

Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder brought on by physical and/or psychological trauma. How its symptoms, including anxiety, depression and cognitive disturbances arise remains incompletely understood and unpredictable.

29 Dec 2020

Study offers explanation for silent hypoxemia in COVID-19 patients

One of the physiopathological characteristics of COVID-19 that has most baffled the scientific and medical community is what is known as "silent hypoxemia" or "happy hypoxia".

29 Dec 2020

Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease

Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients.

29 Dec 2020

Neurologists say there is no medical justification for neck restraints in policing

Some police departments in the United States continue to teach officers that neck restraints are a safe method for controlling agitated or aggressive people, but that's a dangerous myth, according to a Viewpoint written by three neurologists at Massachusetts General Hospital (MGH) in JAMA Neurology.

28 Dec 2020

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether. This is called chromosomal instability, and scientists at Memorial Sloan Kettering have learned that it is associated with cancer's aggressiveness.

28 Dec 2020

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

A new study led by clinician-scientists from the National Cancer Centre Singapore, with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes.

28 Dec 2020

New studies uncover link between vaping and mental fog

Two new studies from the University of Rochester Medical Center have uncovered an association between vaping and mental fog. Both adults and kids who vape were more likely to report difficulty concentrating, remembering, or making decisions than their non-vaping, non-smoking peers.

28 Dec 2020

The evolving role of platelet-rich plasma in cosmetic procedures

Platelet-rich plasma (PRP) treatment, which involves injecting a small amount of a patient's own blood to release various growth factors from platelets, continues to increase in popularity.

28 Dec 2020

Scientists decode music-evoked emotions in the brain

Researchers at the University of Turku have discovered what type of neural mechanisms are the basis for emotional responses to music.

28 Dec 2020

Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine.

24 Dec 2020

SARS-CoV-2 spike-antibody binding strength and hydrogen bond numbers are temperature dependent, study finds

A new preprint on the bioRxiv* server describes the interactions between the binding spike protein of the SARS-CoV-2 virus with the antibodies. Earlier studies have addressed the similarity in the 3D structures of the spike protein in the two SARS viruses as seen on cryo-EM.

24 Dec 2020

Medical Science News

Sugar-binding protein could promote inflammation and worsen sepsis

Epigenetic modulators have a rapid antidepressant-like effect, study shows

Inflammation marker linked to increased fatigue in prostate cancer patients treated with ADT

Six clearly distinguishable subtypes of prediabetes identified

People with detectable brown fat less likely to suffer cardiac and metabolic conditions

Smoking traditional cigarettes along with e-cigarettes causes harmful health effects

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

Scientists design experimental gut-brain system in a lab dish

Anesthesia and sleep have surprisingly similar effects on brain activity, finds study

Brain scans predict posttraumatic stress disorder following mild TBI

Study offers explanation for silent hypoxemia in COVID-19 patients

Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease

Neurologists say there is no medical justification for neck restraints in policing

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

New studies uncover link between vaping and mental fog

The evolving role of platelet-rich plasma in cosmetic procedures

Scientists decode music-evoked emotions in the brain

Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

SARS-CoV-2 spike-antibody binding strength and hydrogen bond numbers are temperature dependent, study finds

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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