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SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Researchers at Yale University School of Medicine found that SARS-CoV-2 viral loads in saliva are higher for patients with associated risk factors and underlying conditions that lead to severe COVID-19 and death. Thus, saliva viral loads could be used to predict disease severity.

7 Jan 2021

Males at higher risk of severe COVID-19 and mortality in Indian case study

A new US-based study by researchers at Dartmouth College, the Development Data Lab, IDFC Institute, Johns Hopkins University, and the University of Chicago shows that the infection fatality rate (IFR) could be twice as high for men compared to women and increases much less at older ages compared to high-income countries.

7 Jan 2021

Which strain should SARS-CoV-2 vaccine candidates target?

A researcher at Clemson University, USA, has recently explored how governments might effectively combat the pandemic through strategic vaccination as new variants and strains of the virus emerge. The study suggests that vaccine candidates should target the fast-spreading variant, even when the initial prevalence is much lower.

7 Jan 2021

Common gene expression changes at target tissues of four autoimmune diseases found

Autoimmune diseases are diseases of "mistaken identity", where the immune system - which is supposed to protect us against infectious diseases and neoplasias - mistakenly attacks and destroys components of our own body.

7 Jan 2021

Scientists aim to understand bone-conducted speech transmission process

The perception of our own voice depends on sound transmission through air (air-conducted) as well as through the skull bone (bone-conducted or BC). The transmission properties of BC speech are, however, not well understood.

7 Jan 2021

Study opens the way for a potential new cure for children with hard-to-treat neuroblastoma

Researchers at the University of Gothenburg now suggest a possible cure for children with hard-to-treat forms of neuroblastoma using a new combination of drugs.

7 Jan 2021

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

A team of scientists from the University of Valencia and INCLIVA Health Research Institute, Spain, has recently investigated the durability of immune responses specifically developed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

7 Jan 2021

Novel low molecular weight dextran-sulphate could play a key role in glaucoma treatment

Scientists at the University of Birmingham, UK, have shown that a novel low molecular weight dextran-sulphate, ILB® could play a key role in treating open angle glaucoma (OAG), a neurodegenerative disease that affects over 70 million people worldwide and causes irreversible blindness.

7 Jan 2021

Researchers use nanotechnology to develop new coronavirus mask model

A US-based research team designed and fabricated electrospun nanofibrous air filters that hold promise for applications in personal protective equipment and indoor environments. The team compared the filtration efficiency of coronavirus and NaCl aerosols to a broad spectrum of electrospun air filters and face masks.

7 Jan 2021

Mass spectrometry imaging shows promise in diagnosing brain diseases

Medical professionals all want to be able to quickly and correctly diagnose diseases. Their future ability to do so will depend on identifying what biochemicals are present in tissue sections, where the biomolecules are, and at what concentrations.

7 Jan 2021

MD Anderson and Xencor to develop novel antibody therapeutics to treat cancer patients

The University of Texas MD Anderson Cancer Center and Xencor, Inc. today announced a strategic research collaboration and commercialization agreement to develop novel CD3 bispecific antibody therapeutics for the potential treatment of patients with cancer.

7 Jan 2021

CytoDel successfully delivers neuronal antibody in animal models of botulism

CytoDel, Inc., a privately-held corporation, today announces the publication of preclinical data on the Company's lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. The complete text of the article titled, "Neuronal Delivery of Antibodies has Therapeutic Effects in Animal Models of Botulism," can be found here.

7 Jan 2021

New approach can help identify novel treatments for autoimmune diseases

A team of researchers led by the Indiana Biosciences Research Institute Diabetes Center's Scientific Director Decio L. Eizirik, MD, PhD, has found that identifying new treatments for autoimmune diseases requires studying together the immune system AND target tissues.

7 Jan 2021

Study investigates control mechanism that ensures accurate chromosome inheritance during cell division

Starting as a single cell, organisms undergo millions of generations of divisions to ultimately generate the bones, heart, brain and other components that make up a living being.

6 Jan 2021

Main bioactive compound of ginger root may protect against autoimmune disease progression

Naturopathic medicine, or herbal medicine, is all the rage, especially among young people. But how much of this is supported by science?

6 Jan 2021

Using a blood test to predict Alzheimer's disease risk during symptom-free stage

Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer's disease in people who were clinically diagnosed as not having Alzheimer's disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD).

6 Jan 2021

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant's intestinal lining, is often connected to the development of severe brain injury in those infants who survive.

6 Jan 2021

Study highlights an important link between dietary fiber intake and depression

Fiber is a commonly recommended part of a healthy diet. That's because it's good for your health in so many ways--from weight management to reducing the risk of diabetes, heart disease, and some types of cancer.

6 Jan 2021

Huntington’s disease mutant gene affects brain and body growth in childhood

There is growing evidence to support the hypothesis that there is a neurodevelopmental component to the late-onset neurodegeneration occurring in the brain of huntingtin gene (HTT gene) mutation carriers, and that this increased susceptibility to brain cell death begins during childhood.

6 Jan 2021

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

A large clinical trial, known as the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-2), is set to take place, which aims to test monoclonal antibody efficacy and safety in people who have mild or moderate COVID-19.

6 Jan 2021

Medical Science News

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Males at higher risk of severe COVID-19 and mortality in Indian case study

Which strain should SARS-CoV-2 vaccine candidates target?

Common gene expression changes at target tissues of four autoimmune diseases found

Scientists aim to understand bone-conducted speech transmission process

Study opens the way for a potential new cure for children with hard-to-treat neuroblastoma

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

Novel low molecular weight dextran-sulphate could play a key role in glaucoma treatment

Researchers use nanotechnology to develop new coronavirus mask model

Mass spectrometry imaging shows promise in diagnosing brain diseases

MD Anderson and Xencor to develop novel antibody therapeutics to treat cancer patients

CytoDel successfully delivers neuronal antibody in animal models of botulism

New approach can help identify novel treatments for autoimmune diseases

Study investigates control mechanism that ensures accurate chromosome inheritance during cell division

Main bioactive compound of ginger root may protect against autoimmune disease progression

Using a blood test to predict Alzheimer's disease risk during symptom-free stage

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Study highlights an important link between dietary fiber intake and depression

Huntington’s disease mutant gene affects brain and body growth in childhood

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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